Further evidence for a novel receptor for amino-terminal parathyroid hormone-related protein on keratinocytes and squamous carcinoma cell lines
Orloff J, Kats Y, Urena P, Schipani E, Vasavada R, Philbrick W, Behal A, Abou-Samra A, Segre G, Jüppner H. Further evidence for a novel receptor for amino-terminal parathyroid hormone-related protein on keratinocytes and squamous carcinoma cell lines. Endocrinology 1995, 136: 3016-3023. DOI: 10.1210/en.136.7.3016.Peer-Reviewed Original ResearchSquamous carcinoma cell linesType I receptorSquamous cell linesCarcinoma cell linesI receptorSquamous cellsCell linesPolyadenylated RNAPTH/PTHrP receptorCloned type I receptorsMessenger RNAAmino-terminal PTHPTH target tissuesComplementary DNAReceptor messenger RNAParathyroid hormone-related proteinRegion-specific DNA probesReceptor complementary DNAResponse to PTHrPSquamous carcinoma cellsHormone-related proteinHybridized to probesPTH-related peptideType II receptorRegion-specific probesFurther evidence for a novel receptor for amino-terminal parathyroid hormone-related protein on keratinocytes and squamous carcinoma cell lines
Orloff J, Kats Y, Urena P, Schipani E, Vasavada R, Philbrick W, Behal A, Abou-Samra A, Segre G, Jüppner H. Further evidence for a novel receptor for amino-terminal parathyroid hormone-related protein on keratinocytes and squamous carcinoma cell lines. Endocrinology 1995, 136: 3016-3023. PMID: 7789327, DOI: 10.1210/endo.136.7.7789327.Peer-Reviewed Original ResearchMeSH KeywordsBase SequenceBlotting, NorthernCarcinoma, Squamous CellCyclic AMPDNA ProbesGene ExpressionHumansKeratinocytesMolecular Sequence DataParathyroid HormoneParathyroid Hormone-Related ProteinPeptide FragmentsProteinsRadioligand AssayReceptor, Parathyroid Hormone, Type 1Receptors, Parathyroid HormoneRNA, MessengerTransfectionTumor Cells, CulturedConceptsSquamous carcinoma cell linesSquamous cell linesPTH/PTHrP receptorType I receptorCarcinoma cell linesI receptorSquamous cellsPTHrP receptorCell linesCommon PTH/PTHrP receptorParathyroid hormone-related proteinType INormal keratinocytesAmino-terminal PTHMessenger RNAHormone-related proteinReceptor messenger RNAPTH target tissuesIntracellular cAMP responseSqCC/Y1 cellsSquamous carcinoma cellsStrong RNA signalsReceptor complementary DNAType II receptorIntracellular calciumCell Type-specific Secretion of Parathyroid Hormone-related Protein via the Regulated versus the Constitutive Secretory Pathway∗
Plawner L, Philbrick W, Burtis W, Broadus A, Stewart A. Cell Type-specific Secretion of Parathyroid Hormone-related Protein via the Regulated versus the Constitutive Secretory Pathway∗. Journal Of Biological Chemistry 1995, 270: 14078-14084. PMID: 7775469, DOI: 10.1074/jbc.270.23.14078.Peer-Reviewed Original ResearchConceptsNon-neuroendocrine cellsConstitutive pathwayRegulated pathwayCell typesRegulated secretory pathwayNeuroendocrine cellsNeuroendocrine cell typesDaughter peptidesSecretory pathwayRegulated fashionMature secretory formsConstitutive fashionSecretory formPathwayHormone-related proteinProteinCellsPolypeptide hormonesPathway usePeptidesParathyroid hormone-related proteinSecretion of PTHrPSecretionSecretory