1987
Developmental therapeutics and the acquired immunodeficiency syndrome.
DeVita V, Broder S, Fauci A, Kovacs J, Chabner B. Developmental therapeutics and the acquired immunodeficiency syndrome. Annals Of Internal Medicine 1987, 106: 568-81. PMID: 2435201, DOI: 10.7326/0003-4819-106-4-568.Peer-Reviewed Original ResearchConceptsHuman T-lymphotropic virus type IIIPotential screening targetsTreatment of AIDST4 subsetOverwhelming infectionImmunodeficiency syndromeOpportunistic infectionsDevelopmental therapeuticsImmune competenceAntiviral drugsViral DNA polymeraseScreening targetsType IIIInfectionAIDSViral integrationDrugsSpecific targetsEncouraging resultsPatientsSyndromeLymphocytes
1979
Clinical characteristics of Pneumocystis carinii pneumonia.
Geelhoed G, Hubbard S, Powell R, Doppman J, DeVita V. Clinical characteristics of Pneumocystis carinii pneumonia. The American Surgeon 1979, 45: 293-304. PMID: 313176.Peer-Reviewed Original Research
1976
Treatment of Pneumocystis carinii pneumonia: current status of the regimens of pentamidine isethionate and pyrimethamine-sulfadiazine.
Young R, DeVita V. Treatment of Pneumocystis carinii pneumonia: current status of the regimens of pentamidine isethionate and pyrimethamine-sulfadiazine. National Cancer Institute Monograph 1976, 43: 193-200. PMID: 1087955.Peer-Reviewed Original ResearchConceptsPyrimethamine-sulfadiazinePneumocystis pneumoniaPentamidine isethionateClinical trialsPneumocystis carinii pneumoniaManagement of patientsSeverely ill patientsRandomized clinical trialsCarinii pneumoniaLocal toxicityRegimensIll patientsPatientsComplete recoveryPneumoniaPneumocystisIsethionateComparative toxicityTrialsPentamidineToxicityPneumocystis pneumonia in patients with cancer: clinical setting.
DeVita V, Goodell B, Hubbard S, Geelhoed G, Young R. Pneumocystis pneumonia in patients with cancer: clinical setting. National Cancer Institute Monograph 1976, 43: 41-7. PMID: 1087959.Peer-Reviewed Original ResearchConceptsPneumocystis pneumoniaClinical settingTreated with combination chemotherapyDevelopment of Pneumocystis pneumoniaWithdrawal of chemotherapyCombination chemotherapyClinical remissionHematologic malignanciesEmpirical treatmentSolid tumorsInfectious deathCancer patientsPatientsPentamidine isethionatePneumoniaAcute formChemotherapyTumorCancerRemissionUncontrolled growthMalignancyPneumocystisPneumocystis Pneumonia
MICHAELIS L, LEIGHT G, POWELL R, DEVITA V. Pneumocystis Pneumonia. Annals Of Surgery 1976, 183: 301-306. PMID: 1083218, PMCID: PMC1344242, DOI: 10.1097/00000658-197603000-00016.Peer-Reviewed Original ResearchConceptsOpen lung biopsyMajor surgical proceduresSmall anterior thoracotomyCause of deathEarly thoracotomyAnterior thoracotomyLung biopsyMost patientsPulmonary infectionIll patientsSusceptible patientsInappropriate therapyGeneral anesthesiaInfected patientsPneumocystis pneumoniaHematologic malignanciesTherapeutic courseSurgical proceduresEffective treatmentPatientsPneumocystis cariniiInfectionThoracotomyTreatmentImmediate identification
1972
An Increasing Awareness of Pneumocystis carinii Pneumonitis
Robbins J, DeVita V. An Increasing Awareness of Pneumocystis carinii Pneumonitis. The Annals Of Thoracic Surgery 1972, 14: 445-447. PMID: 4538515, DOI: 10.1016/s0003-4975(10)65252-6.Peer-Reviewed Original Research
1970
Pneumocystis carinii Pneumonia.
Mansour N, DeVita V, Goodell B. Pneumocystis carinii Pneumonia. Annals Of Internal Medicine 1970, 73: 342-3. PMID: 5311515, DOI: 10.7326/0003-4819-73-2-342.Peer-Reviewed Original ResearchPentamidine: Clinical pharmacologic correlations in man and mice
Waalkes T, Denham C, DeVita V. Pentamidine: Clinical pharmacologic correlations in man and mice. Clinical Pharmacology & Therapeutics 1970, 11: 505-512. PMID: 5310706, DOI: 10.1002/cpt1970114505.Peer-Reviewed Original ResearchConceptsDiffuse interstitial pneumoniaInterstitial pneumoniaUrinary excretionPlasma levelsPneumocystis cariniiSingle intraperitoneal injectionTypes of pneumoniaDosage scheduleCancer patientsMalignant diseaseRenal abnormalitiesConcomitant useIntraperitoneal injectionIntramuscular administrationOrgan transplantationExcretion patternsPatientsPneumoniaPentamidineExcretionDrugsMenDiseaseMiceCariniiPneumocystis carinii: the spectrum of diffuse interstitial pneumonia in patients with neoplastic diseases.
Goodell B, Jacobs J, Powell R, DeVita V. Pneumocystis carinii: the spectrum of diffuse interstitial pneumonia in patients with neoplastic diseases. Annals Of Internal Medicine 1970, 72: 337-40. PMID: 5308994, DOI: 10.7326/0003-4819-72-3-337.Peer-Reviewed Original Research
1969
Needle biopsy in pseudocystis carinii pneumonia.
Jacobs J, Vogel C, Powell R, DeVita V. Needle biopsy in pseudocystis carinii pneumonia. Radiology 1969, 93: 525-30. PMID: 5307241, DOI: 10.1148/93.3.525.Peer-Reviewed Original ResearchPneumocystis carinii Pneumonia — Successful Diagnosis and Treatment of Two Patients with Associated Malignant Processes
DeVita V, Emmer M, Levine A, Jacobs B, Berard C. Pneumocystis carinii Pneumonia — Successful Diagnosis and Treatment of Two Patients with Associated Malignant Processes. New England Journal Of Medicine 1969, 280: 287-291. PMID: 5303991, DOI: 10.1056/nejm196902062800602.Peer-Reviewed Original ResearchConceptsNeedle biopsyMalignant processPentamidine isethionatePneumocystis carinii pneumoniaProper clinical settingPotential renal toxicityRenal functionAdequate therapyCarinii pneumoniaRenal toxicityPneumocystis infectionTubular disordersTherapeutic efficacyClinical settingFurther experiencePatientsBiopsyIsethionateTherapyInfectionDiagnosisValid assessmentPneumoniaPhysiciansDose
1968
Pneumocystis carinii pneumonia.
Vogel C, Cohen M, Powell R, DeVita V. Pneumocystis carinii pneumonia. Annals Of Internal Medicine 1968, 68: 97-108. PMID: 5299825, DOI: 10.7326/0003-4819-68-1-97.Peer-Reviewed Original Research