1993
Glucose suppresses superoxide generation in normal neutrophils: interference in phospholipase D activation
Ortmeyer J, Mohsenin V. Glucose suppresses superoxide generation in normal neutrophils: interference in phospholipase D activation. American Journal Of Physiology 1993, 264: c402-c410. PMID: 8383432, DOI: 10.1152/ajpcell.1993.264.2.c402.Peer-Reviewed Original ResearchConceptsNormal neutrophilsActivation of PLDNADPH oxidaseTreatment of neutrophilsReceptor-mediated stimulationN-formyl-MetPLD activationDiabetic subjectsFormation of inositolReceptor stimulationPhosphoinositide hydrolysisGlucose suppressesIntracellular Ca2NeutrophilsPhospholipase D activationMarked inhibitionLeu-PhePhospholipase D activityGeneration of O2D activationNonmetabolizable sugarPhosphatidic acidSuperoxide anionActivationGlucose
1991
Unsaturated phosphatidylcholines inhibit superoxide production in human neutrophils
Yoshida K, Mohsenin V. Unsaturated phosphatidylcholines inhibit superoxide production in human neutrophils. Life Sciences 1991, 49: 1359-1365. PMID: 1656156, DOI: 10.1016/0024-3205(91)90200-u.Peer-Reviewed Original ResearchMeSH KeywordsAnalysis of VarianceCell FractionationDiglyceridesEnzyme ActivationHumansKineticsNeutrophilsN-Formylmethionine Leucyl-PhenylalaninePhosphatidylcholinesProtein KinasesSuperoxidesTetradecanoylphorbol Acetate