1996
Adaptation of Lung Antioxidants to Cigarette Smoking in Humans
Hilbert J, Mohsenin V. Adaptation of Lung Antioxidants to Cigarette Smoking in Humans. CHEST Journal 1996, 110: 916-920. PMID: 8874245, DOI: 10.1378/chest.110.4.916.Peer-Reviewed Original ResearchConceptsLung lavage cellsBeta-carotene levelsVitamin EBAL cellsLavage cellsMicronutrient antioxidantsSuperoxide dismutaseGPx activityAntioxidant enzyme activitiesWeeks of supplementationBeta-carotene concentrationsGlutathione peroxidase activityIntracellular superoxide dismutaseFree radical scavengerSerum levelsCigarette smokersCigarette smokingControl subjectsBronchoalveolar cellsLung antioxidantsSmokersNonsmokersConcentration of vitaminSOD activityEnzyme activity
1991
Lipid peroxidation and antielastase activity in the lung under oxidant stress: role of antioxidant defenses
Mohsenin V. Lipid peroxidation and antielastase activity in the lung under oxidant stress: role of antioxidant defenses. Journal Of Applied Physiology 1991, 70: 1456-1462. PMID: 2055821, DOI: 10.1152/jappl.1991.70.4.1456.Peer-Reviewed Original ResearchConceptsElastase inhibitory capacityAlveolar lining fluidLipid peroxidation productsLining fluidLavage fluidVitamin-supplemented groupOxidant stressLipid peroxidationPeroxidation productsControl groupLower respiratory tract fluidFour-week supplementationVitamin CRespiratory tract fluidNO2 exposureInactivation of alphaConjugated dienesVitamin supplementationNormal subjectsAntielastase activityInhibitory capacityOxidant exposureSignificant decreaseAntioxidant defensePeroxidation
1988
Airway responsiveness and prostaglandin generation in scorbutic guinea pigs.
Mohsenin V, Tremml P, Rothberg K, Souhrada M, Douglas J. Airway responsiveness and prostaglandin generation in scorbutic guinea pigs. Prostaglandins Leukotrienes And Essential Fatty Acids 1988, 33: 149-55. PMID: 3186781.Peer-Reviewed Original ResearchConceptsAirway smooth muscleAirway hyperresponsivenessProstaglandin generationGuinea pigsAirway responsivenessHistamine aerosolSmooth muscleScorbutic guinea pigsAscorbic acid-deficient dietSignificant airway hyperresponsivenessScorbutic animalsSodium pump activityElectrogenic sodium pump activityAscorbic acid deficiencyProstanoid generationLung parenchymaDeficient dietElectrophysiological characteristicsControl animalsHyperresponsivenessAcid deficiencyControl groupElectrophysiological propertiesScorbutic conditionLung
1987
Effect of Vitamin C on NO2-induced Airway Hyperresponsiveness in Normal Subjects: A Randomized Double-Blind Experiment
Mohsenin V. Effect of Vitamin C on NO2-induced Airway Hyperresponsiveness in Normal Subjects: A Randomized Double-Blind Experiment. American Journal Of Respiratory And Critical Care Medicine 1987, 136: 1408-1411. PMID: 3318598, DOI: 10.1164/ajrccm/136.6.1408.Peer-Reviewed Original ResearchVitamin C and Airways
MOHSENIN V, DuBOIS A. Vitamin C and Airways. Annals Of The New York Academy Of Sciences 1987, 498: 259-268. PMID: 3304063, DOI: 10.1111/j.1749-6632.1987.tb23766.x.Peer-Reviewed Original Research
1983
Effect of Ascorbic Acid on Response to Methacholine Challenge in Asthmatic Subjects1–3
Mohsenin V, Dubois A, Douglas J. Effect of Ascorbic Acid on Response to Methacholine Challenge in Asthmatic Subjects1–3. American Journal Of Respiratory And Critical Care Medicine 1983, 127: 143-7. PMID: 6830027, DOI: 10.1164/arrd.1983.127.2.143.Peer-Reviewed Original Research