2014
Increased Plasma YKL-40/Chitinase-3-Like-Protein-1 Is Associated with Endothelial Dysfunction in Obstructive Sleep Apnea
Jafari B, Elias JA, Mohsenin V. Increased Plasma YKL-40/Chitinase-3-Like-Protein-1 Is Associated with Endothelial Dysfunction in Obstructive Sleep Apnea. PLOS ONE 2014, 9: e98629. PMID: 24878721, PMCID: PMC4039537, DOI: 10.1371/journal.pone.0098629.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaFlow-mediated vasodilationVascular endothelial growth factorYKL-40/chitinaseApnea-hypopnea indexPlasma YKL-40YKL-40Endothelial dysfunctionVasodilatory capacitySleep apneaEndothelial-dependent vasodilatory capacityHypertensive OSANormotensive OSAApparent cardiovascular diseaseRisk of hypertensionProtein 1Events/hrEndothelial growth factorN-OSAVEGF receptor 1Oxygen desaturationSFlt-1Cardiovascular diseaseCommon disorderPositive correlation
2006
Chronic obstructive pulmonary disease and sleep: the interaction.
Urbano F, Mohsenin V. Chronic obstructive pulmonary disease and sleep: the interaction. Panminerva Medica 2006, 48: 223-30. PMID: 17215794.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseObstructive pulmonary diseasePulmonary diseaseSevere chronic obstructive pulmonary diseaseRespiratory muscle fatigueRight ventricular overloadElevated pulmonary pressuresUpper airway resistanceFourth leading causeFunctional residual capacityGoal of therapyOxyhemoglobin dissociation curveProfound adverse effectsMillion adultsResultant hypoxemiaOxygen desaturationPulmonary rehabilitationPulmonary pressureVentricular overloadAirway resistanceRespiratory driveSmoking cessationMorning fatigueLung mechanicsSleep disturbances
1995
Sleep apnea in patients with hemispheric stroke
Mohsenin V, Valor R. Sleep apnea in patients with hemispheric stroke. Archives Of Physical Medicine And Rehabilitation 1995, 76: 71-76. PMID: 7811179, DOI: 10.1016/s0003-9993(95)80046-8.Peer-Reviewed Original ResearchConceptsSleep-disordered breathingHemispheric strokeCerebral symptomsSleep apneaStroke patientsRapid eye movement (REM) sleepArterial oxygen desaturationComplications of strokePresence of hypertensionRespiratory disturbance indexBody mass indexAbnormal sleep architectureEye movement sleepSlow-wave sleepOxygen desaturationGroups of subjectsBrainstem lesionsCerebrovascular accidentCerebral strokeMass indexRespiratory disturbancesRespiratory eventsMovement sleepSleep architecturePrior history
1994
Daytime oxygen saturation does not predict nocturnal oxygen desaturation in patients with chronic obstructive pulmonary disease
Mohsenin V, Guffanti E, Hilbert J, Ferranti R. Daytime oxygen saturation does not predict nocturnal oxygen desaturation in patients with chronic obstructive pulmonary disease. Archives Of Physical Medicine And Rehabilitation 1994, 75: 285-289. PMID: 8129580, DOI: 10.1016/0003-9993(94)90030-2.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseNocturnal oxygen desaturationObstructive pulmonary diseaseOxygen desaturationAwake SaO2Nocturnal hypoxemiaPulmonary diseaseOxygen saturationDaytime oxygen saturationArterial oxygen saturationControl of breathingNocturnal SaO2COPD patientsPulmonary hypertensionAwake patientsPathologic mechanismsIndividual patientsNocturnal oximetryCardiac arrhythmiasPatientsSaO2HypoxemiaDesaturationOximetryDisease