Uma Reddy, MD, MPH
Professor Adjunct of Obstetrics, Gynecology & Reproductive SciencesAbout
Titles
Professor Adjunct of Obstetrics, Gynecology & Reproductive Sciences
Biography
Dr. Reddy graduated from Brown University Magna cum laude and received her M.D. degree from the Warren Alpert Medical School of Brown University. Dr. Reddy also earned a Masters in Public Health (M.P.H.) from the Johns Hopkins Bloomberg School of Public Health. She completed her residency in Obstetrics and Gynecology at the Johns Hopkins Hospital and remained there as a Robert Wood Johnson Clinical Scholar. She completed her Maternal-Fetal Medicine fellowship at Thomas Jefferson University. She was a faculty member at the University of Maryland School of Medicine prior to joining the National Institutes of Health (NIH) as a Medical Officer in the Pregnancy and Perinatology Branch of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). During her tenure at NIH, she provided MFM clinical services at Walter Reed Medical Center (Bethesda, MD) and then Medstar Washington Hospital Center (Washington, DC) as a Professor of Obstetrics and Gynecology at the Georgetown University School of Medicine prior to joining Yale in 2018.
While at NIH, she oversaw many of the largest and most influential studies in obstetrics, including directing the Maternal-Fetal Medicine Units (MFMU) Network which funds multiple clinical trials across the country. Her research on stillbirth as part of the Stillbirth Collaborative Research Network (SCRN), preterm birth and labor management has had a profound impact on obstetrical practice both in the United States and internationally. She received numerous NIH awards for her role in advancing women’s health research agenda nationally.
Dr. Reddy is widely recognized as a scholar, educator, and mentor. Dr. Reddy has been selected to serve as a Member of the American College of Obstetrics and Gynecology (ACOG) Committee on Practice Bulletins – Obstetrics; Fellow of the American Gynecological & Obstetrical Society and was selected as Fellow in Executive Leadership in Academic Medicine (ELAM) Program for Women, 2020-2021 Class. She has published 250 peer reviewed articles, many in the most impactful journals including NEJM and JAMA.
Dr. Reddy is board certified in Obstetrics and Gynecology and Maternal-Fetal Medicine. Her expertise is in the management of high-risk pregnancies complicated by prior preterm birth or pregnancy loss as well as maternal conditions such as diabetes, hypertension, and connective tissue disorders such as lupus.
Departments & Organizations
- Improving Clinical Care for Recurrent Pregnancy Loss
- Yale Center for Genomic Health
Education & Training
- Fellow
- Thomas Jefferson University (2000)
- MPH
- Johns Hopkins Bloomberg School of Public Health, Biostatistics (1999)
- Robert Wood Johnson Clinical Scholar
- Johns Hopkins University (1997)
- Resident
- Johns Hopkins Hospital (1995)
- Intern
- Johns Hopkins Hospital (1992)
- MD
- The Warren Alpert Medical School of Brown University (1991)
- ScB
- Brown University, Biology (1988)
Research
Overview
Medical Research Interests
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Heping Zhang, PhD
Audrey Merriam, MD, MS
Katherine Harper Campbell, MD, MPH
Lena Sweeney
Xiao Xu, PhD, MA
Jennifer Culhane
Pregnant Women
Publications
2024
Improving care after stillbirth
Sweeney L, Reddy U, Xu X. Improving care after stillbirth. American Journal Of Obstetrics And Gynecology 2024 PMID: 39547349, DOI: 10.1016/j.ajog.2024.11.009.Peer-Reviewed Original ResearchThe relationship between perceived discrimination and reported nutrient intake among pregnant individuals of minoritized racial and ethnic groups
Johnson T, Kan A, Bonner L, Van Horn L, Kershaw K, Grobman W, Lindsay K, Debbink M, Mercer B, Haas D, Saade G, Reddy U, Parry S, Simhan H, Robinson D. The relationship between perceived discrimination and reported nutrient intake among pregnant individuals of minoritized racial and ethnic groups. Journal Of The Academy Of Nutrition And Dietetics 2024 PMID: 39542239, DOI: 10.1016/j.jand.2024.11.007.Peer-Reviewed Original ResearchConceptsTotal energy intakeFalse discovery rate correctionPerceived discriminationNutrient intakeEnergy intakeMonths prior to pregnancySaturated fatIntake of total fatRisk of adverse pregnancy outcomesBlock Food Frequency QuestionnaireNulliparous Pregnancy Outcomes StudyIntake of saturated fatMonitoring Mothers-to-BeIntake of dietary fiberFood frequency questionnaireSecondary data analysisAdverse pregnancy outcomesMothers-to-bePregnancy Outcomes StudyEthnic groupsMultivariate regression modelFood frequencyFrequency questionnairePreconception periodPregnancy outcomesThe association of higher offspring early‐childhood weight gain with prepregnancy metabolic and bariatric surgery
Hilaire M, Babcock A, White G, Masson C, Salem R, Reddy U, Gallagher D, LeDuc C, Thaker V. The association of higher offspring early‐childhood weight gain with prepregnancy metabolic and bariatric surgery. Obesity 2024, 32: 2012-2023. PMID: 39497631, DOI: 10.1002/oby.24166.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsOffspring growth trajectoriesBariatric surgeryHypertensive disorders of pregnancyWorld Health Organization Child Growth StandardsRoux-en-Y gastric bypassWeight gainHigher BMI z-scoreEarly-life weight gainNon-MB groupDisorders of pregnancyGestational diabetes mellitusGestational weight gainLow birth weightBMI z-scoreChild Growth StandardsScore-matched controlsPrepregnancy BMIGestational outcomesHypertensive disordersSleeve gastrectomyGastric bypassBirth weightPrepregnancyDiabetes mellitusGrowth standardsAdherence to recommended prenatal visit schedules and risk for stillbirth, according to probable cause of death
Cersonsky T, Ayala N, Tucker N, Saade G, Dudley D, Pinar H, Silver R, Reddy U, Lewkowitz A. Adherence to recommended prenatal visit schedules and risk for stillbirth, according to probable cause of death. European Journal Of Obstetrics & Gynecology And Reproductive Biology 2024, 303: 159-164. PMID: 39488137, DOI: 10.1016/j.ejogrb.2024.10.037.Peer-Reviewed Original ResearchConceptsRisk of stillbirthCause of deathIncreased risk of stillbirthHypertensive disordersPrenatal visit scheduleStillbirth Collaborative Research NetworkHigher risk of stillbirthSuboptimal prenatal careHypertensive disorders of pregnancyAssociated with higher riskDisorders of pregnancyVisit adherenceVisitation guidelinesPrenatal careSecondary analysisNon-adherenceVisit scheduleStillbirthIncreased riskMultivariate regressionStudy objectiveVisit frequencyPregnancyAdherenceGuidelinesOxytocin regimen used for induction of labor and pregnancy outcomes
REDDY U, SANDOVAL G, TITA A, SILVER R, MALLETT G, Kim H, EL-SAYED Y, RICE M, WAPNER R, ROUSE D, SAADE G, THORP J, CHAUHAN S, COSTANTINE M, CHIEN E, CASEY B, SRINIVAS S, SWAMY G, SIMHAN H, MACONES G, GROBMAN W, Network E. Oxytocin regimen used for induction of labor and pregnancy outcomes. American Journal Of Obstetrics & Gynecology MFM 2024, 6: 101508. PMID: 39357802, DOI: 10.1016/j.ajogmf.2024.101508.Peer-Reviewed Original ResearchConceptsInduction of laborLow-risk nulliparous patientsOxytocin regimensAdjusted relative risksAdjusted odds ratiosCesarean deliveryComposite of perinatal deathConfidence intervalsNeonatal respiratory supportLow-dose regimensHigh-dose oxytocin regimenSevere neonatal complicationsOperative vaginal delivery rateFrequency of cesarean deliverySecondary analysisEstimate adjusted relative risksElective induction of laborPerinatal deathRoutine induction of labourEstimate adjusted odds ratiosVaginal delivery rateRespiratory supportNulliparous patientsMHD groupMultivariable Poisson regressionPatient and Community Centered Approaches to Sepsis Among Birthing People
Richardson B, Cepin A, Grilo S, Moss R, Moller M, Brown S, Goffman D, Friedman A, Reddy U, Hall K. Patient and Community Centered Approaches to Sepsis Among Birthing People. Seminars In Perinatology 2024, 48: 151974. PMID: 39341761, DOI: 10.1016/j.semperi.2024.151974.Peer-Reviewed Original ResearchConceptsMaternal health equityHealth equityAcademic-community research partnershipsSevere maternal morbidityCo-designed interventionsBirthing peopleMaternal deathsUnderserved communitiesMaternal morbidityMoms studyResearch partnershipsSepsis-related morbidityCommunity centered approachRisk periodResearch principalsResearch processCentered approachCommunityMorbidityPeoplePostpartumInterventionEquityPartnershipBirthThe association between perinatal depressive symptoms and child neurodevelopment
Miller E, Costantine M, Mele L, Varner M, Reddy U, Wapner R, Thorp J, Saade G, Tita A, Rouse D, Sibai B, Mercer B, Caritis S, Casey B, Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network B. The association between perinatal depressive symptoms and child neurodevelopment. American Journal Of Obstetrics & Gynecology MFM 2024, 6: 101488. PMID: 39293588, DOI: 10.1016/j.ajogmf.2024.101488.Peer-Reviewed Original ResearchConceptsSocial determinants of healthPerinatal depressive symptomsDeterminants of healthDepression screeningYears of ageDepressive symptomsSocial determinantsCES-DPositive postpartum depression screenAntenatal depression screeningPerinatal depression screeningPostpartum depression screeningCES-D <Child neurodevelopmentOne-year postpartumAdverse neurodevelopmental outcomesMulticenter randomized trialMultivariate logistic regressionBirthing peoplePerinatal depressionYear postpartumChild cognitive outcomesIQ score <Thyroxine therapyNeurodevelopmental outcomesBlood Pressure Control in Pregnant Patients with Chronic Hypertension and Diabetes: Should <130/80 be the Target?
Harper L, Kuo H, Boggess K, Dugoff L, Sibai B, Lawrence K, Hughes B, Bell J, Aagaard K, Edwards R, Gibson K, Haas D, Plante L, Metz T, Casey B, Esplin S, Longo S, Hoffman M, Saade G, Hoppe K, Foroutan J, Tuuli M, Owens M, Simhan H, Frey H, Rosen T, Palatnik A, August P, Reddy U, Kinzler W, Su E, Krishna I, Nguyen N, Norton M, Skupski D, El-Sayed Y, Galis Z, Ambalavanan N, Oparil S, Szychowski J, Tita A. Blood Pressure Control in Pregnant Patients with Chronic Hypertension and Diabetes: Should <130/80 be the Target? American Journal Of Obstetrics And Gynecology 2024 PMID: 39288828, DOI: 10.1016/j.ajog.2024.09.006.Peer-Reviewed Original ResearchAltmetricConceptsTarget blood pressureNeonatal intensive care unitLow blood pressure groupBlood pressure groupPerinatal outcomesAverage blood pressureChronic hypertensionMm HgBlood pressureCesarean deliveryNeonatal deathDiastolic BPRisk of NICU admissionCompare perinatal outcomesEvaluate risk ratiosLt;130/80 mm HgPreterm birth <Adverse perinatal outcomesMultivariable log-binomial regression modelsGoal blood pressureAverage diastolic BPPrimary composite outcomeSystolic BP <Log-binomial regression modelsAntenatal blood pressureLarge-Scale Proteomics in Early Pregnancy and Hypertensive Disorders of Pregnancy
Greenland P, Segal M, McNeil R, Parker C, Pemberton V, Grobman W, Silver R, Simhan H, Saade G, Ganz P, Mehta P, Catov J, Merz C, Varagic J, Khan S, Parry S, Reddy U, Mercer B, Wapner R, Haas D. Large-Scale Proteomics in Early Pregnancy and Hypertensive Disorders of Pregnancy. JAMA Cardiology 2024, 9: 791-799. PMID: 38958943, PMCID: PMC11223045, DOI: 10.1001/jamacardio.2024.1621.Peer-Reviewed Original ResearchAltmetricConceptsArea under the receiver operating characteristic curveCase-control studyHypertensive disordersEarly pregnancyClinical dataSmall-for-gestational-age infantsPrediction of hypertensive disordersSmall-for-gestational-ageHypertensive disorders of pregnancyPrediction of HDPDisorders of pregnancyNested case-control studyPlasma samplesMulticenter observational studyStored plasma samplesReceiver operating characteristic curveBody mass indexGestational hypertensionNon-Hispanic blacksPreterm birthFetal sexFirst-trimesterNon-Hispanic whitesPregnancy outcomesMaternal raceCannabis Exposure and Adverse Pregnancy Outcomes Related to Placental Function
Metz T, Allshouse A, McMillin G, Greene T, Chung J, Grobman W, Haas D, Mercer B, Parry S, Reddy U, Saade G, Simhan H, Silver R. Cannabis Exposure and Adverse Pregnancy Outcomes Related to Placental Function. Obstetric Anesthesia Digest 2024, 44: 139-140. DOI: 10.1097/01.aoa.0001026572.72882.bd.Peer-Reviewed Original ResearchConceptsExposure to cannabisCannabis usePlacental functionPregnancy outcomesPrevalence of cannabis usePoor fetal growthAdverse pregnancy outcomesInfluence pregnancy outcomePlacental dysfunctionCannabis exposureFetal growthPregnant individualsSelf-reported useTobacco useCannabisDrug usePregnancyOutcome relationsPotential legal consequencesOutcomesAssociationExposureUseDysfunctionPublished research
Academic Achievements & Community Involvement
honor NICHD Individual Merit Award for leading the Opioid Research Effort
National AwardThe Eunice Kennedy Shriver National Institute for Child Health and Human DevelopmentDetails01/01/2017United Stateshonor NICHD Merit Award for NICHD Clinical Trials Stewardship Working Group
National AwardThe Eunice Kennedy Shriver National Institute for Child Health and Human DevelopmentDetails12/01/2015United Stateshonor National Institutes Office of the Director Honor Award for Team to Re-Engineer Scientific Oversight of Women and Minority Inclusion
National AwardNational Institutes OfficeDetails01/01/2015United Stateshonor National Institutes of Health Director’s Group Award for Pregnancy and Perinatology Branch Stillbirth Research Team
National AwardNational InstitutesDetails01/01/2014United Stateshonor National Institutes of Health Merit Award for Leadership of stillbirth research that has contributed to the successful accomplishment of the NICHD mission
National AwardThe Eunice Kennedy Shriver National Institute for Child Health and Human DevelopmentDetails01/01/2012United States
News
News
- July 02, 2021
Repeat Pregnancy Loss Will Be Focus of Genetic Study
- September 17, 2020
A Pregnancy Ended by COVID-19 Informs New Understanding and Protocols
- September 01, 2020Source: Journal of Clinical Investigation
Yale OB COVID Study Makes the Cover of JCI
- May 29, 2020Source: Nature Medicine
Nature Medicine's COVID-19 Research in Brief: 9 May to 15 May, 2020