2014
Copy Number Variation in Obsessive-Compulsive Disorder and Tourette Syndrome: A Cross-Disorder Study
McGrath LM, Yu D, Marshall C, Davis LK, Thiruvahindrapuram B, Li B, Cappi C, Gerber G, Wolf A, Schroeder FA, Osiecki L, O'Dushlaine C, Kirby A, Illmann C, Haddad S, Gallagher P, Fagerness JA, Barr CL, Bellodi L, Benarroch F, Bienvenu OJ, Black DW, Bloch MH, Bruun RD, Budman CL, Camarena B, Cath DC, Cavallini MC, Chouinard S, Coric V, Cullen B, Delorme R, Denys D, Derks EM, Dion Y, Rosário MC, Eapen V, Evans P, Falkai P, Fernandez TV, Garrido H, Geller D, Grabe HJ, Grados MA, Greenberg BD, Gross-Tsur V, Grünblatt E, Heiman GA, Hemmings SM, Herrera LD, Hounie AG, Jankovic J, Kennedy JL, King RA, Kurlan R, Lanzagorta N, Leboyer M, Leckman JF, Lennertz L, Lochner C, Lowe TL, Lyon GJ, Macciardi F, Maier W, McCracken JT, McMahon W, Murphy DL, Naarden AL, Neale BM, Nurmi E, Pakstis AJ, Pato MT, Pato CN, Piacentini J, Pittenger C, Pollak Y, Reus VI, Richter MA, Riddle M, Robertson MM, Rosenberg D, Rouleau GA, Ruhrmann S, Sampaio AS, Samuels J, Sandor P, Sheppard B, Singer HS, Smit JH, Stein DJ, Tischfield JA, Vallada H, Veenstra-VanderWeele J, Walitza S, Wang Y, Wendland JR, Shugart YY, Miguel EC, Nicolini H, Oostra BA, Moessner R, Wagner M, Ruiz-Linares A, Heutink P, Nestadt G, Freimer N, Petryshen T, Posthuma D, Jenike MA, Cox NJ, Hanna GL, Brentani H, Scherer SW, Arnold PD, Stewart SE, Mathews CA, Knowles JA, Cook EH, Pauls DL, Wang K, Scharf JM. Copy Number Variation in Obsessive-Compulsive Disorder and Tourette Syndrome: A Cross-Disorder Study. Journal Of The American Academy Of Child & Adolescent Psychiatry 2014, 53: 910-919. PMID: 25062598, PMCID: PMC4218748, DOI: 10.1016/j.jaac.2014.04.022.Peer-Reviewed Original ResearchAdolescentDiagnostic and Statistical Manual of Mental DisordersDNA Copy Number VariationsFemaleGenetic Predisposition to DiseaseGenome-Wide Association StudyHumansMaleObsessive-Compulsive DisorderPolymorphism, Single NucleotideTourette Syndrome
2010
Elevated Functional Connectivity Along a Corticostriatal Loop and the Mechanism of Auditory/Verbal Hallucinations in Patients with Schizophrenia
Hoffman RE, Fernandez T, Pittman B, Hampson M. Elevated Functional Connectivity Along a Corticostriatal Loop and the Mechanism of Auditory/Verbal Hallucinations in Patients with Schizophrenia. Biological Psychiatry 2010, 69: 407-414. PMID: 21145042, PMCID: PMC3039042, DOI: 10.1016/j.biopsych.2010.09.050.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlgorithmsAntipsychotic AgentsCerebral CortexDiagnostic and Statistical Manual of Mental DisordersFemaleFrontal LobeHallucinationsHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleNeostriatumNeural PathwaysNeuropsychological TestsPutamenSchizophreniaSchizophrenic PsychologySocioeconomic FactorsTemporal LobeVerbal BehaviorConceptsHealthy control subjectsControl subjectsFunctional connectivityNonhallucinating patientsPatient groupInferior frontal gyrusAuditory/verbal hallucinationsCorticostriatal loopsElevated functional connectivityVerbal hallucinationsFalse discovery rate correctionFunctional magnetic resonancePatientsSubcortical regionsLeft inferior frontal gyrusSeed regionPutamenFrontal gyrusSpeech processing networkFunctional coordinationNeural activitySchizophreniaFC relativeHigh levelsHallucinations