2024
Assessment of the productivity loss due to leading maternal ill-health conditions: a follow-up study of a prospective pregnancy cohort in rural Sri Lanka
Gunarathna S, Wickramasinghe N, Agampodi T, Prasanna I, Agampodi S. Assessment of the productivity loss due to leading maternal ill-health conditions: a follow-up study of a prospective pregnancy cohort in rural Sri Lanka. BMJ Open 2024, 14: e082798. PMID: 39477261, PMCID: PMC11529687, DOI: 10.1136/bmjopen-2023-082798.Peer-Reviewed Original ResearchConceptsIll-health conditionsRural Sri LankaPregnant womenPregnancy cohortFollow-up study of womenFollow-up studyProspective pregnancy cohortRajarata Pregnancy CohortSecondary outcome measuresMonthly household expenditureVaginal bleedingProductivity lossStudy of womenPrimary outcome measurePregnancy follow-upMedical careOutcome measuresHigher absenteeismNausea and vomitingPresenteeismHighest prevalenceAbsenteeismThird trimesterWomenRecommended priorities
2023
Out-of-Pocket Expenditure for Antenatal Care Amid Free Health Care Provision: Evidence From a Large Pregnancy Cohort in Rural Sri Lanka
Gunarathna S, Wickramasinghe N, Agampodi T, Prasanna I, Agampodi S. Out-of-Pocket Expenditure for Antenatal Care Amid Free Health Care Provision: Evidence From a Large Pregnancy Cohort in Rural Sri Lanka. Global Health Science And Practice 2023, 11: e2200410. PMID: 37903576, PMCID: PMC10615247, DOI: 10.9745/ghsp-d-22-00410.Peer-Reviewed Original ResearchConceptsMean OOP expenditureAntenatal careLarge pregnancy cohortPrivate health facilitiesPregnant womenHealth facilitiesOOP expenditureMaternal morbidityIndependent predictorsPrevious pregnancyPregnancy cohortHealth service utilizationInterviewer-administered questionnaireSignificant independent predictorsGovernment health facilitiesGovernment health servicesCare modeLaboratory investigationsHealth care usersSelf-administered questionnaireSri Lankan settingMonthly household incomeHealth care provisionANC visitsThird trimesterIncorporating early pregnancy mental health screening and management into routine maternal care: experience from the Rajarata Pregnancy Cohort (RaPCo), Sri Lanka
Agampodi T, Amarasinghe G, Wickramasinghe A, Wickramasinghe N, Warnasekara J, Jayasinghe I, Hettiarachchi A, Nimesha D, Dilshani T, Senadheera S, Agampodi S. Incorporating early pregnancy mental health screening and management into routine maternal care: experience from the Rajarata Pregnancy Cohort (RaPCo), Sri Lanka. BMJ Global Health 2023, 8: e012852. PMID: 37748792, PMCID: PMC10533714, DOI: 10.1136/bmjgh-2023-012852.Peer-Reviewed Original ResearchConceptsEdinburgh Postnatal Depression ScaleMental health screeningMental health problemsPregnancy cohortSecond trimesterEarly pregnancyHealth screeningClinical InterviewHealth problemsPregnancy care programsRoutine maternal careTertiary care hospitalMental health service provisionPrimary healthcare levelHigher EPDS scoresPostnatal Depression ScaleWeeks of periodPregnancy-associated conditionsMental health gapPatient-centered careHealth service provisionHealth surveillance systemsCare hospitalMiddle-income countriesPregnant womenPerinatal mental health in Sri Lanka, current status, programmes, gaps, and recommendations.
Agampodi T, Agampodi S. Perinatal mental health in Sri Lanka, current status, programmes, gaps, and recommendations. Ceylon Medical Journal 2023, 68: 53-57. PMID: 37610969, DOI: 10.4038/cmj.v68isi 1.9792.Peer-Reviewed Original ResearchChallenges of Continuation of Exclusive Breast Feeding up to 6 Months in a Setting with High Exclusive Breast Feeding Rates Reported. Experience from Eastern Province of Sri Lanka
Ranasinghe J, Madushika D, Abeysundara S, Agampodi S. Challenges of Continuation of Exclusive Breast Feeding up to 6 Months in a Setting with High Exclusive Breast Feeding Rates Reported. Experience from Eastern Province of Sri Lanka. Maternal And Child Health Journal 2023, 27: 1996-2001. PMID: 37270754, DOI: 10.1007/s10995-023-03724-2.Peer-Reviewed Original ResearchConceptsExclusive breastfeedingNon-exclusive breastfeedingExclusive breast feeding ratesPublic Health Midwife areasDescriptive cross-sectional studyEarly cessationResultsThe mean ageBreast feeding ratesCross-sectional studyWorld Breastfeeding Trends InitiativeExclusive breastSingle centerMean ageMaternal ageChildren 1Risk factorsOdds ratioBreastfeedingMonthsMedical officersUnemployed mothersHealth areaSignificant predictorsBirth orderMothersImpact of COVID-19 pandemic on health service utilisation and household economy of pregnant and postpartum women: a cross-sectional study from rural Sri Lanka
Gunarathna S, Wickramasinghe N, Agampodi T, Prasanna I, Agampodi S. Impact of COVID-19 pandemic on health service utilisation and household economy of pregnant and postpartum women: a cross-sectional study from rural Sri Lanka. BMJ Open 2023, 13: e070214. PMID: 37247958, PMCID: PMC10230333, DOI: 10.1136/bmjopen-2022-070214.Peer-Reviewed Original ResearchConceptsCurrent economic crisisHousehold economyFree public health servicesFinancial assistanceNon-parametric analysisEconomic crisisEconomic dataMonthly household incomeSri LankaHealth service utilisationHousehold incomeEconomic componentCOVID-19 pandemicEconomyPovertyIncomeService utilisationRural Sri LankaPostpartum womenCross-sectional studyPregnant womenAnuradhapura districtPublic health servicesLankaHealthcare utilisationEarly pregnancy metabolic syndrome and risk for adverse pregnancy outcomes: findings from Rajarata Pregnancy Cohort (RaPCo) in Sri Lanka
Jayasinghe I, Agampodi T, Dissanayake A, Agampodi S. Early pregnancy metabolic syndrome and risk for adverse pregnancy outcomes: findings from Rajarata Pregnancy Cohort (RaPCo) in Sri Lanka. BMC Pregnancy And Childbirth 2023, 23: 231. PMID: 37020187, PMCID: PMC10074348, DOI: 10.1186/s12884-023-05548-y.Peer-Reviewed Original ResearchConceptsGestational agePreterm birthPregnancy outcomesPregnant womenMetabolic syndromePregnancy cohortJoint Interim Statement criteriaFirst trimester pregnant womenMajor pregnancy outcomesSouth Asian pregnant womenAdverse pregnancy outcomesNeonatal birth weightGestational weight gainMedian gestational ageProspective cohort studyLive singleton birthsSignificant risk predictorAsian pregnant womenConclusionPregnant womenFPG thresholdMetS prevalenceCohort studyCumulative incidenceProspective cohortMetS definitionsDeterminants of birthweight in rural Sri Lanka; a cohort study
Banda P, Amarasinghe G, Agampodi S. Determinants of birthweight in rural Sri Lanka; a cohort study. BMC Pediatrics 2023, 23: 40. PMID: 36690991, PMCID: PMC9869565, DOI: 10.1186/s12887-022-03830-0.Peer-Reviewed Original ResearchConceptsMother-infant cohortPregnant womenCohort studyPreterm birthPsychosocial wellbeingThird trimester pregnant womenPerinatal health issuesProspective cohort studySocioeconomic statusPrimary care levelMaternal care servicesAntenatal care programsHusband's education levelSelf-completed questionnaireMiddle-income settingsEducation levelHierarchical logistic regressionPregnancy registrationHypertensive disordersMaternal BMISingleton pregnanciesThird trimesterBaby's sexChronic diabetesPerinatal health
2022
The geo-spatial perspective of biological, social and environmental determinants of early pregnancy anaemia in rural Sri Lanka: Need for context-specific approaches on prevention
Amarasinghe G, Agampodi T, Mendis V, Agampodi S. The geo-spatial perspective of biological, social and environmental determinants of early pregnancy anaemia in rural Sri Lanka: Need for context-specific approaches on prevention. Geospatial Health 2022, 17 PMID: 36468596, DOI: 10.4081/gh.2022.1110.Peer-Reviewed Original ResearchConceptsPrevalence of anemiaEarly pregnancyPregnant womenRisk factorsFirst trimester pregnant womenHigher anemia prevalenceAntenatal care programsEnvironmental risk factorsHeterogeneous risk factorsMaternal anemiaPregnancy anemiaPregnancy cohortAnemia prevalenceDietary patternsHigh prevalenceAnemiaCare programRural Sri LankaPrevalenceSocioeconomic disparitiesPregnancyHealth DivisionEthnic distributionSignificant differencesAnuradhapura districtFactors associated with early pregnancy anemia in rural Sri Lanka: Does being ‘under care’ iron out socioeconomic disparities?
Amarasinghe G, Agampodi T, Mendis V, Agampodi S. Factors associated with early pregnancy anemia in rural Sri Lanka: Does being ‘under care’ iron out socioeconomic disparities? PLOS ONE 2022, 17: e0274642. PMID: 36201463, PMCID: PMC9536542, DOI: 10.1371/journal.pone.0274642.Peer-Reviewed Original ResearchConceptsPregnancy anemiaPregnant womenFirst trimester pregnant womenSocioeconomic disparitiesRisk of anemiaOdds of anemiaFull blood countHistory of anemiaContinuum of carePeriod of gestationFamily Health ProgramHierarchical logistic regression modelsSelf-completed questionnaireLogistic regression modelsHealth care coveragePublic health infrastructureMaternal anemiaAntenatal careCohort studyBreast feedingContraceptive injectionMiddle-income countriesAnemia preventionRegression modelsAnemia controlThe magnitude of out‐of‐pocket expenditure for antenatal care in low and middle‐income countries: A systematic review and meta‐analysis
Gunarathne SP, Wickramasinghe ND, Agampodi TC, Prasanna IR, Agampodi SB. The magnitude of out‐of‐pocket expenditure for antenatal care in low and middle‐income countries: A systematic review and meta‐analysis. The International Journal Of Health Planning And Management 2022, 38: 179-203. PMID: 36129403, DOI: 10.1002/hpm.3578.Peer-Reviewed Original ResearchHelp-seeking intention for depression and suicidal ideation during pregnancy and postpartum in rural Sri Lanka, a cross-sectional study
Amarasinghe GS, Agampodi SB. Help-seeking intention for depression and suicidal ideation during pregnancy and postpartum in rural Sri Lanka, a cross-sectional study. Rural And Remote Health 2022, 22: 7273. PMID: 36059212, DOI: 10.22605/rrh7273.Peer-Reviewed Original ResearchConceptsSymptoms of depressionPublic health midwivesCross-sectional studyPregnant womenSuicidal ideationSuicidal thoughtsRural Sri LankaMental illnessHelp-seeking patternsHelp-seeking intentionsCommon mental illnessResource-constrained settingsMental health professionalsMaternal morbidityAntenatal clinicCurrent pregnancyMaternal deathsNumerous morbiditiesPeripartum depressionPostpartum mothersPostpartum periodMaternal depressionVignette-based questionnaireRisk populationsHealth professionalsAsthma in a prospective cohort of rural pregnant women from Sri Lanka: Need for better care during the pre-conceptional and antenatal period
Rajapakse S, Wickramasinghe N, Warnasekara J, Abeyrathna P, Amarasinghe G, Hettiarachchi AU, Jayasinghe IU, Koralegedara I, Agampodi TC, Agampodi SB. Asthma in a prospective cohort of rural pregnant women from Sri Lanka: Need for better care during the pre-conceptional and antenatal period. PLOS ONE 2022, 17: e0269888. PMID: 35834567, PMCID: PMC9282538, DOI: 10.1371/journal.pone.0269888.Peer-Reviewed Original ResearchConceptsNew-onset wheezePregnant womenSecond trimesterAsthmatic womenPregnancy outcomesPregnant asthmatic womenEligible pregnant womenProspective cohort studyLow birth weightPrevalence of wheezeEffect of asthmaRural pregnant womenMaternal care programmeCohort studyProspective cohortHospital admissionAntenatal periodAsthma prevalenceFirst trimesterBirth weightClinical assessmentHigh prevalenceWheezeAsthmaTrimesterFatty Liver Index is a valid predictor of non-alcoholic fatty liver disease (NAFLD) in pregnancy
Koralegedara IS, Warnasekara JN, Rathnayake A, Dayaratne KG, Agampodi SB. Fatty Liver Index is a valid predictor of non-alcoholic fatty liver disease (NAFLD) in pregnancy. BMJ Open Gastroenterology 2022, 9: e000913. PMID: 35728866, PMCID: PMC9214354, DOI: 10.1136/bmjgast-2022-000913.Peer-Reviewed Original ResearchConceptsNon-alcoholic fatty liver diseaseFatty liver indexAdverse pregnancy outcomesFatty liver diseasePregnant womenPregnancy outcomesLiver diseaseFatty liverLiver indexFirst trimester pregnant womenGamma-glutamyl transferase levelsBody mass indexPeriod of gestationLogistic regression modelsBinary logistic regression modelIndependent predictorsMass indexPregnancy cohortEarly pregnancyMean ageTransferase levelsLiver enzymesUltrasound scanGeneral populationHealth setupFeasibility of using telephone interviews and internet-based message services during the COVID-19 pandemic in rural Sri Lanka: experiences of the Rajarata Pregnancy Cohort
Jayasinghe I, Wickramasinghe Y, Kurera DM, Samarakoon N, Rupasinghe I, Ponmalay P, Agampodi SB. Feasibility of using telephone interviews and internet-based message services during the COVID-19 pandemic in rural Sri Lanka: experiences of the Rajarata Pregnancy Cohort. Rural And Remote Health 2022, 22: 7442. PMID: 35546146, DOI: 10.22605/rrh7442.Peer-Reviewed Original ResearchConceptsTelephone interviewsPregnancy cohortCOVID-19 pandemicTelephone-based strategyHealth message deliveryHealth promotion initiativesLow-resource settingsPregnant womenPopulation health researchersRural Sri LankaPromotion initiativesHealth disparitiesRural areasCohortSelection biasHealth researchersMiddle-income nationsPandemicDeliveryParticipantsLocal settingProper assessmentImplementation of researchSettingSri LankaCross-sectional study to assess etiology and associated factors for anaemia during first trimester of pregnancy in Anuradhapura District, Sri Lanka: a protocol.
Amarasinghe G, Mendis V, Agampodi T, Agampodi S. Cross-sectional study to assess etiology and associated factors for anaemia during first trimester of pregnancy in Anuradhapura District, Sri Lanka: a protocol. F1000Research 2022, 10: 223. PMID: 35528960, PMCID: PMC9039368, DOI: 10.12688/f1000research.28226.3.Peer-Reviewed Original ResearchConceptsStrong public health systemCross-sectional studyPregnant womenFirst trimesterSignificant global health problemEtiology of anemiaInterviewer-administered questionnaireComplete blood countGlobal health problemPublic health systemAnuradhapura districtDietary questionnaireFetal outcomesMaternal anemiaAntenatal careAnemia controlBlood countSectional studyAnemia casesAnemiaHealth problemsPregnancySimilar etiologyField clinicsEtiologyProtocol for systematic review and meta-analysis: magnitude, reasons, associated factors, and implications of the out-of-pocket expenditure during pregnancy
Gunarathne SP, Wickramasinghe ND, Agampodi TC, Prasanna RPIR, Agampodi SB. Protocol for systematic review and meta-analysis: magnitude, reasons, associated factors, and implications of the out-of-pocket expenditure during pregnancy. Public Health 2022, 206: 33-37. PMID: 35349965, DOI: 10.1016/j.puhe.2022.02.018.Peer-Reviewed Original ResearchConceptsEligible studiesSystematic reviewPocket expenditureDatabase-specific subject headingsMaternal health careMixed Methods Appraisal ToolComprehensive literature searchMethods Appraisal ToolWeb of ScienceHealth care policySubgroup analysisThird reviewerIndependent reviewersReference listsElectronic databasesNarrative synthesisLiterature searchManual searchPregnancyStudy designQuality appraisalAppraisal toolHealth careOOPECare policyEconomic burden of out-of-pocket expenditure, productivity cost during pregnancy and COVID-19 impact on household economy in a cohort of pregnant women in Anuradhapura District, Sri Lanka; A study protocol
Gunarathne SP, Wickramasinghe ND, Agampodi TC, Prasanna IR, Agampodi SB. Economic burden of out-of-pocket expenditure, productivity cost during pregnancy and COVID-19 impact on household economy in a cohort of pregnant women in Anuradhapura District, Sri Lanka; A study protocol. F1000Research 2022, 10: 700. PMID: 35528955, PMCID: PMC9046902, DOI: 10.12688/f1000research.53320.3.Peer-Reviewed Original ResearchConceptsPregnant womenMaternal healthProductivity costsEconomic burdenHealth servicesPocket expenditureCOVID-19 outbreakCross-sectional studyAnuradhapura districtTerms of absenteeismHealth care practitionersFree health servicesLack of evidenceStudy protocolHealth care administratorsOngoing COVID-19 pandemicCare practitionersStudy settingCOVID-19 impactPregnancyOOPECohortMedical officersWomenStudy sampleNon-alcoholic fatty liver disease (NAFLD): a significant predictor of gestational diabetes mellitus (GDM) and early pregnancy miscarriages—prospective study in Rajarata Pregnancy Cohort (RaPCo)
Koralegedara IS, Warnasekara JN, Dayaratne KG, De Silva FN, Premadasa JK, Agampodi SB. Non-alcoholic fatty liver disease (NAFLD): a significant predictor of gestational diabetes mellitus (GDM) and early pregnancy miscarriages—prospective study in Rajarata Pregnancy Cohort (RaPCo). BMJ Open Gastroenterology 2022, 9: e000831. PMID: 35193889, PMCID: PMC8867246, DOI: 10.1136/bmjgast-2021-000831.Peer-Reviewed Original ResearchConceptsNon-alcoholic fatty liver diseaseGestational diabetes mellitusEarly pregnancy miscarriageFatty liver diseasePregnancy miscarriageRisk factorsDiabetes mellitusLiver diseasePregnant womenRelative riskEffect of NAFLDImpact of NAFLDPopulation-based prospective cohort studyRepeat oral glucose tolerance testFirst trimester pregnant womenOral glucose tolerance testPregnancy care programsProspective cohort studyOnly independent predictorBody mass indexGlucose tolerance testWeeks of gestationSignificant risk factorsMajor risk factorHigh-risk mothersComparison of global definitions of metabolic syndrome in early pregnancy among the Rajarata Pregnancy Cohort participants in Sri Lanka
Jayasinghe IU, Agampodi TC, Dissanayake AK, Srimantha SM, Agampodi SB. Comparison of global definitions of metabolic syndrome in early pregnancy among the Rajarata Pregnancy Cohort participants in Sri Lanka. Scientific Reports 2022, 12: 2009. PMID: 35132136, PMCID: PMC8821546, DOI: 10.1038/s41598-022-05919-z.Peer-Reviewed Original ResearchConceptsPeriod of gestationTotal cholesterolEarly pregnancyMetabolic syndromeMetabolic derangementsCohort participantsPrevalence estimatesOral glucose tolerance testHigher MetS prevalenceNCEP ATP IIIAHA/NHLBIGlucose tolerance testDifferent diagnostic criteriaSignificant differencesCross-sectional analysisAge 27.9MetS prevalencePregnancy outcomesSerum lipidsMetS definitionsProspective studyPregnant womenPlasma glucoseTolerance testMetabolic parameters