2018
Longitudinal assessment of hippocampus structure in children with type 1 diabetes
Foland‐Ross L, Reiss AL, Mazaika PK, Mauras N, Weinzimer SA, Aye T, Tansey MJ, White NH, Network T. Longitudinal assessment of hippocampus structure in children with type 1 diabetes. Pediatric Diabetes 2018, 19: 1116-1123. PMID: 29675980, PMCID: PMC6195484, DOI: 10.1111/pedi.12683.Peer-Reviewed Original ResearchAge-matched control subjectsType 1 diabetes mellitusHealthy age-matched controlsEffects of dysglycemiaEffect of diabetesRisk of hypoglycemiaHealthy control childrenType 1 diabetesAge-matched controlsGreater glycemic variabilityYoung childrenStructural magnetic resonance imaging (MRI) dataGlycemic exposureDiabetes mellitusControl subjectsGlycemic variabilityHippocampal volumeMagnetic resonance imaging dataHippocampus volumeCognitive alterationsHippocampus structureT1DControl childrenLongitudinal assessmentLongitudinal changes
2016
Future Drug Treatments for Type 1 Diabetes
Sherr J, Cengiz E, Van Name M, Weinzimer S, Tamborlane W. Future Drug Treatments for Type 1 Diabetes. 2016, 985-999. DOI: 10.1002/9781118924853.ch66.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsInsulin analoguesDiabetes mellitusContinuous subcutaneous insulin infusion pumpType 2 diabetes mellitusType 1 diabetes mellitusInsulin deliveryBasal insulin analoguesNew treatment optionsFuture drug treatmentsAvailable insulin analoguesMore rapid absorptionClosed-loop deliveryDaily diabetes careAvailable insulin preparationsInsulin infusion pumpIntranasal glucagonInsulin therapyGlycemic controlAdjunctive agentsAvailable therapiesInjected medicationsDiabetes careTreatment optionsContinuous glucose monitorDrug treatmentAltered Integration of Structural Covariance Networks in Young Children With Type 1 Diabetes
Hosseini SM, Mazaika P, Mauras N, Buckingham B, Weinzimer SA, Tsalikian E, White NH, Reiss AL, Network F. Altered Integration of Structural Covariance Networks in Young Children With Type 1 Diabetes. Human Brain Mapping 2016, 37: 4034-4046. PMID: 27339089, PMCID: PMC5053865, DOI: 10.1002/hbm.23293.Peer-Reviewed Original ResearchConceptsEarly-onset T1DStructural covariance networksYoung childrenNeurocognitive deficitsType 1 diabetes mellitusCovariance networksBrain networksFrequent chronic diseasesHum Brain MappRegional gray matterGlycemic controlDiabetes mellitusGlucose dysregulationNeural insultsHealthy controlsLarge-scale brain networksChronic diseasesBulk of evidenceNeuroanatomical changesT1DWhite matterGray matterBrain developmentGraph theoretical analysisT1D.
2008
Continuous Glucose Monitoring and Intensive Treatment of Type 1 Diabetes
Tamborlane W, Beck R, Bode B, Buckingham B, Chase H, Clemons R, Fiallo-Scharer R, Fox L, Gilliam L, Hirsch I, Huang E, Kollman C, Kowalski A, Laffel L, Lawrence J, Lee J, Mauras N, O'Grady M, Ruedy K, Tansey M, Tsalikian E, Weinzimer S, Wilson D, Wolpert H, Wysocki T, Xing D. Continuous Glucose Monitoring and Intensive Treatment of Type 1 Diabetes. New England Journal Of Medicine 2008, 359: 1464-1476. PMID: 18779236, DOI: 10.1056/nejmoa0805017.Peer-Reviewed Original ResearchConceptsYears of ageContinuous glucose monitoringContinuous monitoring groupPatients 25 yearsGlycated hemoglobin levelsType 1 diabetesHemoglobin levelsGlucose monitoringStudy groupControl groupType 1 diabetes mellitusMulticenter clinical trialBetween-group differencesHemoglobin outcomesYounger patientsDiabetes mellitusGlycemic controlIntensive therapyPrimary outcomeSevere hypoglycemiaClinical trialsIntensive treatmentAge groupsBlood glucose metersType 1
2004
Rediscovery of insulin pump treatment of childhood type 1 diabetes.
Weinzimer SA, Doyle EA, Steffen AT, Sikes KA, Tamborlane WV. Rediscovery of insulin pump treatment of childhood type 1 diabetes. Minerva Medica 2004, 95: 85-92. PMID: 15272243.Peer-Reviewed Original ResearchConceptsContinuous subcutaneous insulin infusionInsulin pump therapyQuality of lifeSevere hypoglycemiaPump therapyLong-term microvascular complicationsEfficacy of CSIIType 1 diabetes mellitusWeight gainChildhood type 1 diabetesExcessive weight gainBasal infusion rateSubcutaneous insulin infusionType 1 diabetesNew insulin analoguesTreatment of childrenContinuous glucose monitoringMicrovascular complicationsDiabetes mellitusPediatric patientsHemoglobin levelsNocturnal hypoglycemiaTreatment optionsNormal glycemiaInsulin infusionDiabetes Mellitus in Children and Adolescents
Weinzimer S, Tamborlane W. Diabetes Mellitus in Children and Adolescents. 2004 DOI: 10.1002/0470862092.d0809.Peer-Reviewed Original ResearchDiabetes mellitusNormal glucose controlRoutine clinical practiceSpecific clinical presentationType 2 diabetesType 1 diabetesQuality of lifeOutpatient managementClinical presentationTreatment algorithmGlucose controlDifferential diagnosisClinical practiceMellitusDiabetesInsulin deliveryPresent unique challengesChildrenArtificial pancreasDiagnosisTreatmentUnique challengesPancreasPrevalenceClinicians