2016
Supported employment and education in comprehensive, integrated care for first episode psychosis: Effects on work, school, and disability income
Rosenheck R, Mueser KT, Sint K, Lin H, Lynde DW, Glynn SM, Robinson DG, Schooler NR, Marcy P, Mohamed S, Kane JM. Supported employment and education in comprehensive, integrated care for first episode psychosis: Effects on work, school, and disability income. Schizophrenia Research 2016, 182: 120-128. PMID: 27667369, DOI: 10.1016/j.schres.2016.09.024.Peer-Reviewed Original ResearchConceptsCommunity carePublic support incomeFirst episode psychosis programUsual community careGeneral estimation equation modelsFirst-episode psychosisEstimation equation modelsPsychosis programPublic support paymentsEpisode psychosisTreatment clinicsDays of participationTreatment approachesFEP participantsIntegrated careStudy participantsTreatment programEvidence effectivenessMonthly assessmentsGroup differencesIndividual PlacementDisability incomeGreater improvementGreater increaseCare
2010
Augmentation with citalopram for suicidal ideation in middle-aged and older outpatients with schizophrenia and schizoaffective disorder who have subthreshold depressive symptoms: a randomized controlled trial.
Zisook S, Kasckow JW, Lanouette NM, Golshan S, Fellows I, Vahia I, Mohamed S, Rao S. Augmentation with citalopram for suicidal ideation in middle-aged and older outpatients with schizophrenia and schizoaffective disorder who have subthreshold depressive symptoms: a randomized controlled trial. The Journal Of Clinical Psychiatry 2010, 71: 915-22. PMID: 20361918, DOI: 10.4088/jcp.09m05699gre.Peer-Reviewed Original ResearchConceptsBaseline suicidal ideationHamilton Depression Rating ScaleDepression Rating ScaleSubthreshold depressive symptomsCalgary Depression Rating ScaleDepressive symptomsSuicidal ideationSchizoaffective disorderClinical Global Impressions-SeverityBeck Hopelessness ScaleDSM-IV-diagnosed schizophreniaRating ScaleTreatment-emergent suicidal ideationPlacebo-controlled trialSuicidal ideation measuresItem 3Citalopram augmentationFinal visitPlacebo augmentationSecondary outcomesPrimary outcomeOlder outpatientsInterSePT ScaleCitalopramPlacebo
2007
Subsyndromal Depressive Symptoms in Middle-Aged and Older Persons with Schizophrenia
Zisook S, Montross L, Kasckow J, Mohamed S, Palmer BW, Patterson TL, Golshan S, Fellows I, Lehman D, Solorzano E. Subsyndromal Depressive Symptoms in Middle-Aged and Older Persons with Schizophrenia. American Journal Of Geriatric Psychiatry 2007, 15: 1005-1014. PMID: 18056819, DOI: 10.1097/jgp.0b013e3180a725ec.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsChronic DiseaseCitalopramComorbidityDepressionDepressive Disorder, MajorDouble-Blind MethodFemaleFollow-Up StudiesHealth StatusHumansMaleMiddle AgedPlacebosPsychiatric Status Rating ScalesPsychotic DisordersSchizophreniaSchizophrenic PsychologySelective Serotonin Reuptake InhibitorsSuicideTreatment OutcomeConceptsSubsyndromal depressive symptomsDepressive symptomsOlder patientsClinical featuresSchizoaffective disorderNegative symptomsHamilton Depression Rating ScaleImportant clinical dimensionGeneral medical conditionsDepression Rating ScaleSpecific depressive symptomsMental functioningSubstantial morbiditySevere akathisiaMovement abnormalitiesChronic schizophreniaMedical conditionsDepression groupOverall psychopathologyIntervention studiesDepressive symptomatologyPatientsSymptomsOlder personsGeneral psychopathology
2005
Stability of Cognitive Performance in Older Patients With Schizophrenia: An 8-Week Test-Retest Study
Harvey PD, Palmer BW, Heaton RK, Mohamed S, Kennedy J, Brickman A. Stability of Cognitive Performance in Older Patients With Schizophrenia: An 8-Week Test-Retest Study. American Journal Of Psychiatry 2005, 162: 110-117. PMID: 15625208, DOI: 10.1176/appi.ajp.162.1.110.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAlgorithmsAmbulatory CareAntipsychotic AgentsCognition DisordersFemaleFollow-Up StudiesHumansMaleMiddle AgedNeuropsychological TestsPsychiatric Status Rating ScalesPsychometricsPsychomotor PerformanceReproducibility of ResultsSchizophreniaSchizophrenic PsychologySeverity of Illness IndexConceptsCognitive measuresCognitive performancePractice effectsComprehensive neuropsychological test batteryTest scoresReliable change index methodCognitive-enhancing medicationsNeuropsychological test batteryCognitive test scoresSignificant test-retest correlationsModest cognitive improvementTest-retest correlationsTest-retest performanceCognitive improvementTest batterySecond-generation antipsychotic medicationsTest-retest errorSchizophrenia patientsRetest studyAntipsychotic medicationAlternate formsConventional antipsychotic medicationsSchizophreniaSpurious improvementPrior studies