2014
Association of symptom severity, insight and increased pharmacologic side effects in acutely hospitalized patients with schizophrenia
Zhang J, Rosenheck R, Mohamed S, Zhou Y, Chang Q, Ning Y, He H. Association of symptom severity, insight and increased pharmacologic side effects in acutely hospitalized patients with schizophrenia. Comprehensive Psychiatry 2014, 55: 1914-1919. PMID: 25217308, DOI: 10.1016/j.comppsych.2014.07.018.Peer-Reviewed Original ResearchConceptsPharmacologic side effectsSevere side effectsGreater medication complianceHigher medication dosagesPANSS total scoreSevere symptomsSide effectsMedication complianceMedication dosageITAQ scoresHigh dosesTotal scorePoor treatment complianceSide effect scoresLarge psychiatric hospitalRelationship of symptomsNegative Syndrome ScaleTreatment Attitudes QuestionnaireStepwise multiple linear regression analysisInteraction of symptomsInsightful patientsTreatment emergentHospital dischargePrescribed medicationsTreatment compliance
2009
Off-Label Use of Antipsychotic Medications in the Department of Veterans Affairs Health Care System
Leslie DL, Mohamed S, Rosenheck RA. Off-Label Use of Antipsychotic Medications in the Department of Veterans Affairs Health Care System. Psychiatric Services 2009, 60: 1175-1181. PMID: 19723731, DOI: 10.1176/ps.2009.60.9.1175.Peer-Reviewed Original ResearchConceptsAntipsychotic medicationLabel useLogistic regression modelsBipolar disorderVeterans Affairs Health Care SystemVeterans AffairsMultivariate logistic regression modelVA administrative databasesHalf of patientsFirst-generation antipsychoticsOff-label useSevere side effectsMental illness diagnosisPosttraumatic stress disorderHealth care systemClinical characteristicsRegression modelsAntipsychotic useVA patientsAdministrative databasesMinor depressionMajor depressionHigher oddsMedicationsSide effects
2004
The Use of Novel Antipsychotics in the Older Patient With Neurodegenerative Disorders in the Long-Term Care Setting
Kasckow J, Mulchahey J, Mohamed S. The Use of Novel Antipsychotics in the Older Patient With Neurodegenerative Disorders in the Long-Term Care Setting. Journal Of The American Medical Directors Association 2004, 5: 242-248. DOI: 10.1097/01.jam.0000129822.54487.14.Peer-Reviewed Original ResearchLong-term care settingsOlder patientsAtypical antipsychoticsCare settingsNeurodegenerative disordersSide effectsDouble-blind placebo-controlled trialHigh-potency conventional antipsychoticsLong-term care patientsOpen-label studyPlacebo-controlled trialNewer atypical antipsychoticsOlder patient populationUse of quetiapineUse of risperidoneExtrapyramidal side effectsAtypical antipsychotic medicationsConventional antipsychoticsCare patientsTardive dyskinesiaNovel antipsychoticsAntipsychotic medicationPatient populationPsychopharmacologic agentsAgitation symptoms
2001
Citalopram augmentation of antipsychotic treatment in older schizophrenia patients
Kasckow J, Mohamed S, Thallasinos A, Carroll B, Zisook S, Jeste D. Citalopram augmentation of antipsychotic treatment in older schizophrenia patients. International Journal Of Geriatric Psychiatry 2001, 16: 1163-1167. PMID: 11748776, DOI: 10.1002/gps.508.Peer-Reviewed Original ResearchConceptsCitalopram augmentationScale scoreClinical Global Impression Scale scoresHamilton Depression Rating Scale scoresLarge double-blind studyDepression Rating Scale scoresAugmentation of antipsychoticsUsefulness of antidepressantsDouble-blind studySingle-blind trialMajor side effectsOlder schizophrenia patientsRating Scale scoresStable dosesElderly patientsOlder patientsAntipsychotic treatmentCitalopram groupDepressive symptomsSide effectsPatientsSchizophrenia patientsControl groupNegative symptomsAntipsychotics