Escitalopram for comorbid depression and anxiety in elderly patients: A 12-week, open-label, flexible-dose, pilot trial
Mohamed S, Osatuke K, Aslam M, Kasckow J. Escitalopram for comorbid depression and anxiety in elderly patients: A 12-week, open-label, flexible-dose, pilot trial. The American Journal Of Geriatric Pharmacotherapy 2006, 4: 201-209. PMID: 17062320, DOI: 10.1016/j.amjopharm.2006.08.001.Peer-Reviewed Original ResearchConceptsMajor depressive disorderComorbid major depressive disorderElderly patientsComorbid depressionEscitalopram 10Adverse eventsPilot trialBaseline Montgomery-Asberg Depression Rating Scale (MADRS) scoreMontgomery-Asberg Depression Rating Scale scoreSecondary efficacy end pointsSelective serotonin reuptake inhibitorsDepression Rating Scale scoresVeterans Affairs Medical CenterEfficacy end pointPrimary efficacy variableMedical Outcomes StudySerotonin reuptake inhibitorsShort-term administrationHAM-A scoresHamilton Rating ScaleLack of efficacyPoor treatment responseRating Scale scoresSymptoms of depressionGreater symptom severity