2022
Childhood adversity and adulthood major depressive disorder
Zisook S, Planeta B, Hicks PB, Chen P, Davis LL, Villarreal G, Sapra M, Johnson GR, Mohamed S. Childhood adversity and adulthood major depressive disorder. General Hospital Psychiatry 2022, 76: 36-44. PMID: 35366613, DOI: 10.1016/j.genhosppsych.2022.03.008.Peer-Reviewed Original ResearchConceptsMajor depressive disorderChildhood adversityDepressive disorderSuicidal ideationLower remission rateLower depression severityDepression Outcomes studyMore lifetime episodesGOV IDENTIFIERRemission rateClinical featuresClinical outcomesSevere depressionTreatment strategiesLifetime episodesOutcome studiesDepression severitySwitching treatmentYounger ageSecondary analysisComorbid PTSDChildhood maltreatmentWorse qualitySpecific typesDisorders
2004
Bipolar Disorder in Middle-Aged and Elderly Adults: Is Age of Onset Important?
Depp CA, Jin H, Mohamed S, Kaskow J, Moore DJ, Jeste DV. Bipolar Disorder in Middle-Aged and Elderly Adults: Is Age of Onset Important? The Journal Of Nervous And Mental Disease 2004, 192: 796-799. PMID: 15505527, DOI: 10.1097/01.nmd.0000145055.45944.d6.Peer-Reviewed Original ResearchConceptsLate-onset groupLate-life bipolar disorderAge of onsetBipolar disorderFamily historyLate-onset bipolar disorderAge 40 yearsContinuous variablesCognitive functioningRelationship of ageOlder patientsMedication useClinical featuresCross-sectional designMedication usageMean ageDepressive symptomsOverall psychopathologyDistinct syndromeElderly adultsMeasures of psychopathologyDisordersNeuropsychological functioningAgeNeurobiological aspects