Outcomes in Patients With Poststroke Seizures
Misra S, Kasner S, Dawson J, Tanaka T, Zhao Y, Zaveri H, Eldem E, Vazquez J, Silva L, Mohidat S, Hickman L, Khan E, Funaro M, Nicolo J, Mazumder R, Yasuda C, Sunnerhagen K, Ihara M, Ross J, Liebeskind D, Kwan P, Quinn T, Engel J, Mishra N. Outcomes in Patients With Poststroke Seizures. JAMA Neurology 2023, 80: 1155-1165. PMID: 37721736, PMCID: PMC10507596, DOI: 10.1001/jamaneurol.2023.3240.Peer-Reviewed Original ResearchConceptsPoststroke seizuresPoor functional outcomeLate seizuresEarly seizuresStroke subtypesFunctional outcomeOdds ratioSystematic reviewJoanna Briggs Institute toolsHemorrhagic stroke subtypesOutcomes of patientsHistory of strokeTrials of interventionsRisk of biasMeta-Analyses (PRISMA) checklistPreferred Reporting ItemsMeta-regression analysisWeb of ScienceRecurrent strokeGreater disabilityPoor outcomeDementia riskSubgroup analysisBias assessmentEgger's testImpact of genetic polymorphisms on the risk of epilepsy amongst patients with acute brain injury: A systematic review
Misra S, Quinn T, Falcone G, Sharma V, de Havenon A, Zhao Y, Eldem E, French J, Yasuda C, Dawson J, Liebeskind D, Kwan P, Mishra N. Impact of genetic polymorphisms on the risk of epilepsy amongst patients with acute brain injury: A systematic review. European Journal Of Neurology 2023, 30: 1791-1800. PMID: 36912749, DOI: 10.1111/ene.15777.Peer-Reviewed Original ResearchConceptsPost-traumatic epilepsyPost-stroke epilepsyTraumatic brain injuryRisk of epilepsySystematic reviewSingle nucleotide polymorphismsBrain injuryOdds ratioRisk of PSERisk of PTEAcute brain injuryGenetic polymorphismsConfidence intervalsAssociation of SNPsQ-Genie toolPSE patientsLate seizuresHazard ratioStroke patientsTBI patientsPrespecified protocolStudy qualityCurrent evidenceEpilepsyPatientsClinical characteristics and outcomes of patients with post-stroke epilepsy: protocol for an individual patient data meta-analysis from the International Post-stroke Epilepsy Research Repository (IPSERR)
Mishra N, Kwan P, Tanaka T, Sunnerhagen K, Dawson J, Zhao Y, Misra S, Wang S, Sharma V, Mazumder R, Funaro M, Ihara M, Nicolo J, Liebeskind D, Yasuda C, Cendes F, Quinn T, Ge Z, Scalzo F, Zelano J, Kasner S, Consortium I, Mishra N, Kwan P, Friedman A, Engel J. Clinical characteristics and outcomes of patients with post-stroke epilepsy: protocol for an individual patient data meta-analysis from the International Post-stroke Epilepsy Research Repository (IPSERR). BMJ Open 2023, 13: e078684. PMID: 37968000, PMCID: PMC10660442, DOI: 10.1136/bmjopen-2023-078684.Peer-Reviewed Original ResearchConceptsPost-stroke epilepsyPost-stroke seizuresIndividual patient dataClinical characteristicsLate post-stroke seizuresPatient dataOutcomes of patientsFuture clinical trialsPatient outcome measuresComprehensive search strategyAcute strokePeer-reviewed journalsStroke patientsPrognostic valueStroke mortalityBias assessmentClinical trialsObservational studyOutcome measuresLanguage of publicationEpileptic seizuresPatientsEthics approvalStudy authorsIPD-MA