2012
Endometrial Shedding Effect on Conception and Live Birth in Women With Polycystic Ovary Syndrome
Diamond M, Kruger M, Santoro N, Zhang H, Casson P, Schlaff W, Coutifaris C, Brzyski R, Christman G, Carr B, McGovern P, Cataldo N, Steinkampf M, Gosman G, Nestler J, Carson S, Myers E, Eisenberg E, Legro R. Endometrial Shedding Effect on Conception and Live Birth in Women With Polycystic Ovary Syndrome. Obstetrical & Gynecological Survey 2012, 67: 548-549. DOI: 10.1097/01.ogx.0000421452.19985.8f.Peer-Reviewed Original ResearchPolycystic ovary syndromeLive birth rateProgestin withdrawalEndometrial sheddingLive birthsAnovulatory womenClomiphene citrateOvary syndromeOvulation inductionSpontaneous mensesProgestin-induced withdrawal bleedingEunice Kennedy Shriver National InstituteBirth rateAdministration of clomipheneOligo-ovulatory womenPrevious bleeding episodesDouble-blind trialFirst-line therapyCommon clinical practiceUse of progestinsOccurrence of ovulationRate of conceptionWithdrawal bleedWithdrawal bleedingBleeding episodes
2007
Clomiphene, Metformin, or Both for Infertility in the Polycystic Ovary Syndrome
Legro R, Barnhart H, Schlaff W, Carr B, Diamond M, Carson S, Steinkampf M, Coutifaris C, McGovern P, Cataldo N, Gosman G, Nestler J, Giudice L, Leppert P, Myers E. Clomiphene, Metformin, or Both for Infertility in the Polycystic Ovary Syndrome. Obstetrical & Gynecological Survey 2007, 62: 386-388. DOI: 10.1097/01.ogx.0000265909.61668.01.Peer-Reviewed Original ResearchPolycystic ovary syndromeExtended-release metforminMetformin groupLive birthsTreatment groupsClomiphene citrateOvary syndromeInfertile womenPregnancy lossSex hormone-binding globulin levelsAbstract Polycystic ovary syndromeHormone-binding globulin levelsFirst trimester pregnancy lossClomiphene-treated patientsDose of clomipheneMetformin-treated womenPlacebo-controlled trialSerious adverse eventsFirst-line treatmentFree androgen indexLive birth rateGastrointestinal side effectsBody mass indexEarly pregnancy lossSingle drug group