2003
Regulatory effect of castration on endothelins, their receptors and endothelin‐converting enzyme in rat seminal vesicle
Takahashi W, Yono M, Wada Y, Ikeda K, Weiss R, Latifpour J. Regulatory effect of castration on endothelins, their receptors and endothelin‐converting enzyme in rat seminal vesicle. BJU International 2003, 92: 803-809. PMID: 14616470, DOI: 10.1046/j.1464-410x.2003.04466.x.Peer-Reviewed Original ResearchConceptsExpression of endothelinETB receptor subtypesET receptorsECE-1 mRNARat seminal vesicleReceptor subtypesSeminal vesiclesET-1Slide-mounted frozen sectionsET receptor systemET-3 mRNATotal ET receptorsETA receptor subtypeSprague-Dawley ratsReverse transcription-polymerase chain reactionExpression levelsExpression of ETAEffects of castrationEndothelin-converting enzymeMultiplex reverse transcription-polymerase chain reactionPolymerase chain reactionSmooth muscleET-3Autoradiographic studyFrozen sections
1998
CHARACTERIZATION, LOCALIZATION AND DISTRIBUTION OF alpha1 ADRENOCEPTOR SUBTYPE IN MALE RABBIT URETHRA
NISHI K, LATIFPOUR J, SAITO M, FOSTER H, YOSHIDA M, WEISS R. CHARACTERIZATION, LOCALIZATION AND DISTRIBUTION OF alpha1 ADRENOCEPTOR SUBTYPE IN MALE RABBIT URETHRA. Journal Of Urology 1998, 160: 196-205. PMID: 9628650, DOI: 10.1016/s0022-5347(01)63090-8.Peer-Reviewed Original ResearchConceptsAlpha1 adrenoceptorsRabbit urethraMale rabbit urethraSelective alpha1-adrenoceptor antagonistAnti-alpha smooth muscle actinAlpha1-adrenoceptor antagonistRabbit urethral smooth muscleUrethral smooth muscleRadioligand receptor bindingSmooth muscle actinSmooth muscle fibersLight microscopic autoradiographySingle high-affinity binding siteAdrenoceptor antagonistBMY 7378Distal urethraWB 4101Immunohistochemical studyPharmacological characterizationSmooth musclePharmacological profileAdrenoceptorsUrethraMuscle actinHigh-affinity binding sites
1997
Muscarinic Receptor Subtypes and Receptor‐Coupled Phosphatidylinositol Hydrolysis in Rat Bladder Smooth Muscle
Mimata H, Nomura Y, Emoto A, Latifpour J, Wheeler M, Weiss R. Muscarinic Receptor Subtypes and Receptor‐Coupled Phosphatidylinositol Hydrolysis in Rat Bladder Smooth Muscle. International Journal Of Urology 1997, 4: 591-596. PMID: 9477190, DOI: 10.1111/j.1442-2042.1997.tb00315.x.Peer-Reviewed Original ResearchConceptsRat bladder smooth muscleBladder smooth muscleMuscarinic receptor subtypesSmooth muscleM3 receptorsReceptor subtypesPI hydrolysisCarbachol stimulationBladder smooth muscle contractionPhosphatidylinositol hydrolysisN-methylpiperidine methiodideRat urinary bladderSubtype-specific antagonistsSmooth muscle contractionProduction of IP3Expression of mRNAContractile responseUrinary bladderSpecific antagonistMuscle contractionBasal levelsInhibitory effectSubtypesReceptorsMuscleAge-dependent changes in particulate and soluble guanylyl cyclase activities in urinary tract smooth muscle
Wheeler M, Pontari M, Dokita S, Nishimoto T, Cho Y, Hong K, Weiss R. Age-dependent changes in particulate and soluble guanylyl cyclase activities in urinary tract smooth muscle. Molecular And Cellular Biochemistry 1997, 169: 115-124. PMID: 9089638, DOI: 10.1023/a:1006823611864.Peer-Reviewed Original ResearchConceptsSoluble guanylyl cyclase activityAdult guinea pigsGuanylyl cyclase activityCyclase activityBladder domeSodium nitroprussideGuinea pigsUrinary tract smooth muscleGuanylyl cyclaseAtrial natriuretic factorParticulate guanylyl cyclaseAge-dependent changesAge-specific differencesUrinary tractNatriuretic factorSmooth muscleUreterUrethraRelaxation responseBladderInduced activationNitroprussideTissueRank orderAge
1991
NG-nitro-L-arginine inhibits non-adrenergic, non-cholinergic relaxation in rabbit urethral smooth muscle
Dokita S, Morgan W, Wheeler M, Yoshida M, Latifpour J, Weiss R. NG-nitro-L-arginine inhibits non-adrenergic, non-cholinergic relaxation in rabbit urethral smooth muscle. Life Sciences 1991, 48: 2429-2436. PMID: 1675415, DOI: 10.1016/0024-3205(91)90377-n.Peer-Reviewed Original ResearchConceptsElectrical field stimulationRelaxation responseNG-nitroField stimulationL-arginineSelective cyclic GMP phosphodiesterase inhibitorNitric oxideNon-cholinergic relaxationRabbit urethral smooth muscleNon-cholinergic nervesUrethral smooth muscleUrethral smooth muscle stripsSmooth muscle stripsL-arginine inhibitsSoluble guanylate cyclaseNitric oxide biosynthesisCyclic GMP phosphodiesterase inhibitorMuscle stripsSmooth musclePhosphodiesterase inhibitorGuanylate cyclaseCyclic GMPStimulationInhibitorsResponse
1989
Characterization of Autonomic Receptors in Neonatal Urinary Tract Smooth Muscle
Latifpour J, Morita T, O'Hollaren B, Kondo S, Weiss R. Characterization of Autonomic Receptors in Neonatal Urinary Tract Smooth Muscle. Neonatology 1989, 13: 1-10. PMID: 2570683, DOI: 10.1159/000457575.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic AgonistsAnimalsAnimals, NewbornCarbacholClonidineDihydroalprenololDose-Response Relationship, DrugIn Vitro TechniquesMuscle ContractionMuscle, SmoothPrazosinQuinuclidinyl BenzilateRabbitsReceptors, Adrenergic, alphaReceptors, Adrenergic, betaReceptors, MuscarinicUrinary TractYohimbineConceptsUrinary tract smooth muscleSmooth muscleAutonomic receptorsBeta-adrenergic receptor densityAlpha-1 adrenergic receptorsNeonatal urinary tractAlpha 2 receptorsAlpha 1 receptorsAlpha-adrenergic agonistsFunctional muscarinic receptorsRelaxant responsesBladder baseBladder domeMuscarinic receptorsUrinary tractReceptor densityAdult rabbitsAlpha 2ReceptorsMuscleAgonistsRank orderRabbitsHigher numberIsoproterenol
1987
Sex differences in function and distribution of alpha 1- and alpha 2-adrenoceptors in rabbit urethra
Morita T, Latifpour J, O'Hollaren B, Wheeler M, Weiss R. Sex differences in function and distribution of alpha 1- and alpha 2-adrenoceptors in rabbit urethra. American Journal Of Physiology 1987, 252: f1124-f1128. PMID: 3035945, DOI: 10.1152/ajprenal.1987.252.6.f1124.Peer-Reviewed Original ResearchConceptsContractile responseFemale urethraMale urethraAlpha 1Rabbit urethraRadioligand receptor binding techniquesFemale rabbit urethraLarger contractile responsesSmall contractile responseAlpha-adrenergic agonistsUrethral smooth muscleReceptor binding techniquesReceptor binding studiesIsolated urethraSmooth muscleContractile propertiesUrethraFemale rabbitsContractile forceAgonistsInduced increasesAlpha 2Binding techniquesNorepinephrineAlphaPreliminary Results with Aminophylline as Smooth-Muscle Relaxant in Percutaneous Renal Surgery
GREEN D, GLICKMAN M, WEISS R. Preliminary Results with Aminophylline as Smooth-Muscle Relaxant in Percutaneous Renal Surgery. Journal Of Endourology 1987, 1: 243-247. DOI: 10.1089/end.1987.1.243.Peer-Reviewed Case Reports and Technical NotesUreteropelvic junctionUpper urinary tractSmooth muscle relaxantSmooth muscle relaxationPercutaneous renal surgeryInfundibular spasmUrinary tractRenal surgeryRenal stonesSmooth muscleCaliceal stonesSpasmPhosphodiesterase inhibitorPatientsAminophyllineStrictureStonesRelaxantsSurgeryPyeloplastyScarringEndopyelotomyTractOcclusion
1986
Relaxant Effect of Forskolin in Rabbit Detrusor Smooth Muscle: Role of Cyclic AMP
Morita T, Wheeler M, Weiss R. Relaxant Effect of Forskolin in Rabbit Detrusor Smooth Muscle: Role of Cyclic AMP. Journal Of Urology 1986, 135: 1293-1295. PMID: 3012124, DOI: 10.1016/s0022-5347(17)46077-0.Peer-Reviewed Original ResearchConceptsDetrusor muscleRelaxant effectRabbit detrusor muscle stripsDetrusor muscle relaxationDetrusor muscle stripsRabbit detrusor muscleConcentration-dependent relaxationDetrusor smooth muscleRabbit detrusor smooth muscleBeta-adrenergic antagonistsBeta-adrenergic receptorsCyclic AMPCyclic AMP levelsAdenylate cyclase inhibitorRabbit detrusorMuscle stripsMuscle relaxationSmooth muscleCyclase inhibitorPhosphodiesterase inhibitorRelaxation responseAMP levelsAdenylate cyclaseDependent relaxationForskolinCharacterization of Functional Beta-Adrenoceptor Subtypes in Rabbit Urinary Bladder Smooth Muscle
MORITA T, KONDO S, TSUCHIDA S, WEISS R. Characterization of Functional Beta-Adrenoceptor Subtypes in Rabbit Urinary Bladder Smooth Muscle. The Tohoku Journal Of Experimental Medicine 1986, 149: 389. PMID: 3022421, DOI: 10.1620/tjem.149.389.Peer-Reviewed Original ResearchConceptsTrigonal muscleRelaxant responsesM isoproterenolRabbit urinary bladder smooth muscleUrinary bladder smooth muscleSignificant relaxant responseSpontaneous contractile forceUrinary bladder domeBeta-adrenoceptor subtypesBeta-adrenoceptor agonistsBeta-adrenoceptor stimulationMaximum relaxant responseBladder smooth muscleM butoxamineM metoprololSelective betaBladder domeMuscle stripsM propranololSpecific betaDetrusorSmooth muscleMale rabbitsIsoproterenolContractile force
1985
Effect of Isoproterenol on Contractile Force of Isolated Rabbit Renal Pelvic Smooth Muscle
MORITA T, MIYAGAWA I, WHEELER M, WEISS R. Effect of Isoproterenol on Contractile Force of Isolated Rabbit Renal Pelvic Smooth Muscle. The Tohoku Journal Of Experimental Medicine 1985, 147: 153. PMID: 4082174, DOI: 10.1620/tjem.147.153.Peer-Reviewed Original Research