2018
Predicting Barriers to Treatment for Depression in a U.S. National Sample: A Cross-Sectional, Proof-of-Concept Study
Chekroud AM, Foster D, Zheutlin AB, Gerhard DM, Roy B, Koutsouleris N, Chandra A, Esposti MD, Subramanyan G, Gueorguieva R, Paulus M, Krystal JH. Predicting Barriers to Treatment for Depression in a U.S. National Sample: A Cross-Sectional, Proof-of-Concept Study. Psychiatric Services 2018, 69: 927-934. PMID: 29962307, PMCID: PMC7232987, DOI: 10.1176/appi.ps.201800094.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overCross-Sectional StudiesDepressive DisorderFemaleHealth Services AccessibilityHumansLogistic ModelsMaleMiddle AgedPatient Acceptance of Health CarePrimary Health CareProof of Concept StudyPsychotherapySampling StudiesSelf-AssessmentSurveys and QuestionnairesTreatment RefusalUnited StatesYoung AdultConceptsDiagnosis of depressionHealth care providersSelf-report survey itemsImplementation of interventionsDerivation cohortUntreated depressionCare providersEffective treatmentU.S. national sampleDrug useDepressionDiagnosisTreatmentU.S. National SurveyPatientsCohortNational surveyNational sampleConcept studySurvey itemsBalanced accuracyIndividualsRetention rateIndependent responsesPrevalence
2015
Predictors of Abstinence From Heavy Drinking During Follow-Up in COMBINE.
Gueorguieva R, Wu R, Fucito LM, O'Malley SS. Predictors of Abstinence From Heavy Drinking During Follow-Up in COMBINE. Journal Of Studies On Alcohol And Drugs 2015, 76: 935-41. PMID: 26562602, PMCID: PMC4712662, DOI: 10.15288/jsad.2015.76.935.Peer-Reviewed Original ResearchMeSH KeywordsAlcohol DrinkingAlcoholismBehavior TherapyFemaleFollow-Up StudiesHumansLogistic ModelsMaleTreatment OutcomeConceptsLong-term outcomesBetter long-term outcomesBetter clinical outcomesDrinking outcomesHeavy drinking daysLogistic regression analysisStrongest predictorLogistic regression modelsPredictors of abstinenceFair classification accuracyPatient characteristicsClinical outcomesTerm outcomesCombined PharmacotherapiesClinical trialsBaseline predictorsTreatment outcomesTreatment phaseOptimizing outcomesDrinking daysBetter outcomesAlcohol Dependence (COMBINE) StudyBehavioral interventionsHeavy drinkingAlternative interventions
2014
Predictors of Abstinence from Heavy Drinking During Treatment in COMBINE and External Validation in PREDICT
Gueorguieva R, Wu R, O'Connor PG, Weisner C, Fucito LM, Hoffmann S, Mann K, O'Malley SS. Predictors of Abstinence from Heavy Drinking During Treatment in COMBINE and External Validation in PREDICT. Alcohol Clinical And Experimental Research 2014, 38: 2647-2656. PMID: 25346505, PMCID: PMC4397985, DOI: 10.1111/acer.12541.Peer-Reviewed Original ResearchAcamprosateAge FactorsAlcohol AbstinenceAlcohol DeterrentsAlcohol DrinkingBehavior TherapyCombined Modality TherapyControlled Clinical Trials as TopicDecision Treesgamma-GlutamyltransferaseGermanyGoalsHumansLogistic ModelsMiddle AgedNaltrexonePredictive Value of TestsRandomized Controlled Trials as TopicReproducibility of ResultsTaurineTime FactorsTreatment OutcomeUnited StatesRates of violence in patients classified as high risk by structured risk assessment instruments
Singh JP, Fazel S, Gueorguieva R, Buchanan A. Rates of violence in patients classified as high risk by structured risk assessment instruments. The British Journal Of Psychiatry 2014, 204: 180-187. PMID: 24590974, PMCID: PMC3939440, DOI: 10.1192/bjp.bp.113.131938.Peer-Reviewed Original ResearchMeSH KeywordsHumansLogistic ModelsPatientsReproducibility of ResultsRisk AssessmentSensitivity and SpecificitySex FactorsViolenceConceptsHigh riskStructured risk assessment instrumentsRates of violenceHigh-risk groupCurrent evidence baseRisk assessment instrumentsStructured professional judgment instrumentSuch risk estimatesFuture violence riskAssessment instrumentsBinomial logistic regressionStudy authorsLogistic regressionEvidence baseRisk estimatesSystematic searchStructured risk assessmentPopulation rates
2009
Adolescent cannabis use increases risk for cocaine-induced paranoia
Kalayasiri R, Gelernter J, Farrer L, Weiss R, Brady K, Gueorguieva R, Kranzler HR, Malison RT. Adolescent cannabis use increases risk for cocaine-induced paranoia. Drug And Alcohol Dependence 2009, 107: 196-201. PMID: 19944543, PMCID: PMC2821949, DOI: 10.1016/j.drugalcdep.2009.10.006.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdolescent BehaviorAge FactorsAge of OnsetCannabisCatechol O-MethyltransferaseCocaine-Related DisordersFemaleGene FrequencyGenetic Predisposition to DiseaseHumansLogistic ModelsMaleParanoid DisordersPolymerase Chain ReactionPrevalencePsychiatric Status Rating ScalesRisk FactorsSeverity of Illness IndexSiblingsUnited StatesConceptsAdolescent onset cannabisEarly cannabis exposureCocaine-dependent individualsCocaine-induced paranoiaCannabis exposureRisk factorsCOMT genotypeSemi-Structured AssessmentCatechol-O-methyl transferase (COMT) geneCOMT Val158Met genotypeCannabis abuseIncrease riskPsychotic symptomsOnset interactionPsychotic disordersStimulant abuseDrug dependenceFamily-based studyLogistic regressionEarly exposureAdolescent cannabisCannabisGenetic factorsSignificant predictorsVal158Met genotype
2007
Opioid Receptor Gene (OPRM1, OPRK1, and OPRD1) Variants and Response to Naltrexone Treatment for Alcohol Dependence: Results From the VA Cooperative Study
Gelernter J, Gueorguieva R, Kranzler HR, Zhang H, Cramer J, Rosenheck R, Krystal JH, Group T. Opioid Receptor Gene (OPRM1, OPRK1, and OPRD1) Variants and Response to Naltrexone Treatment for Alcohol Dependence: Results From the VA Cooperative Study. Alcohol Clinical And Experimental Research 2007, 31: 555-563. PMID: 17374034, DOI: 10.1111/j.1530-0277.2007.00339.x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcoholismConfidence IntervalsDNADouble-Blind MethodExonsFemaleGenetic VariationGenotypeHumansLinear ModelsLogistic ModelsMaleMiddle AgedNaltrexoneNarcotic AntagonistsOdds RatioProportional Hazards ModelsPsychiatric Status Rating ScalesReceptors, Opioid, deltaReceptors, Opioid, kappaReceptors, Opioid, muSmokingTreatment OutcomeUnited StatesUnited States Department of Veterans AffairsConceptsAlcohol dependenceOpioid receptorsTreatment responseVA Cooperative StudyRate of relapsePredictors of responseAlcohol-dependent male subjectsMu-opioid receptorsKappa-opioid receptorsCourse of treatmentShort-term treatmentReceptor gene variantsOpioid receptor geneAsn40Asp polymorphismAvailable medicationsNaltrexone treatmentSpecific pharmacotherapyPretreatment numberDrug naltrexoneNaltrexoneMale subjectsCooperative StudyRelapseHeavy drinkingIndividual single nucleotide polymorphisms
2001
Effect of Teenage Pregnancy on Educational Disabilities in Kindergarten
Gueorguieva R, Carter R, Ariet M, Roth J, Mahan C, Resnick M. Effect of Teenage Pregnancy on Educational Disabilities in Kindergarten. American Journal Of Epidemiology 2001, 154: 212-220. PMID: 11479185, DOI: 10.1093/aje/154.3.212.Peer-Reviewed Original ResearchConceptsLong-term morbidityTeenage pregnancyMaternal ageTeenage mothersOlder maternal ageYoung maternal ageAssociated sociodemographic factorsMarital statusSingle marital statusPublic health issuePerinatal outcomesPoor outcomeHigh prevalenceProtective effectHigher oddsSociodemographic factorsPregnancyMaternal educationYounger ageHealth issuesAdverse effectsTeen ageIndependent effectsEducational disabilitiesMorbidity
1999
The Impact of Low Birth Weight, Perinatal Conditions, and Sociodemographic Factors on Educational Outcome in Kindergarten
Resnick M, Gueorguieva R, Carter R, Ariet M, Sun Y, Roth J, Bucciarelli R, Curran J, Mahan C. The Impact of Low Birth Weight, Perinatal Conditions, and Sociodemographic Factors on Educational Outcome in Kindergarten. Pediatrics 1999, 104: e74-e74. PMID: 10586008, DOI: 10.1542/peds.104.6.e74.Peer-Reviewed Original ResearchConceptsLow birth weightLong-term morbidityBirth weightSociodemographic factorsPerinatal factorsPerinatal conditionsRisk factorsMultivariate analysisAdverse perinatal conditionsStandardized eligibility criteriaTotal birth populationSociodemographic risk factorsOdds of placementGeneralized logistic regressionPrenatal careEducational outcome variablesSevere outcomesCongenital anomaliesEligibility criteriaGreater prevalenceBirth recordsReference categoryLogistic regressionBirth populationSociodemographic predictors