2020
Salivary Immunoglobulin A Secretion and Polymeric Ig Receptor Expression in the Submandibular Glands Are Enhanced in Heat-Acclimated Rats
Matsuzaki K, Sugimoto N, Islam R, Hossain E, Sumiyoshi E, Katakura M, Shido O. Salivary Immunoglobulin A Secretion and Polymeric Ig Receptor Expression in the Submandibular Glands Are Enhanced in Heat-Acclimated Rats. International Journal Of Molecular Sciences 2020, 21: 815. PMID: 32012687, PMCID: PMC7037029, DOI: 10.3390/ijms21030815.Peer-Reviewed Original ResearchConceptsSalivary IgA secretionIgA secretionHeat-acclimated ratsSubmandibular glandIgA flow rateImmunoglobulin A (IgA) secretionMucosal IgA secretionSalivary IgA concentrationMale Wistar ratsSalivary immunoglobulin AHeat acclimationPolymeric Ig receptor expressionPlasma cytokinesCN ratsMucosal immunityOral immunityIL-6IgA concentrationsReceptor expressionImmunoglobulin AWistar ratsSalivary functionHE groupChronic exposurePIgR expression
2019
Theobromine Improves Working Memory by Activating the CaMKII/CREB/BDNF Pathway in Rats
Islam R, Matsuzaki K, Sumiyoshi E, Hossain E, Hashimoto M, Katakura M, Sugimoto N, Shido O. Theobromine Improves Working Memory by Activating the CaMKII/CREB/BDNF Pathway in Rats. Nutrients 2019, 11: 888. PMID: 31010016, PMCID: PMC6520707, DOI: 10.3390/nu11040888.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrainBrain-Derived Neurotrophic FactorCacaoCalcium-Calmodulin-Dependent Protein Kinase Type 2Cyclic AMP Response Element-Binding ProteinDietary SupplementsMaleMaze LearningMemory, Short-TermPhosphorylationPhytotherapyPlant ExtractsRats, WistarRNA, MessengerSignal TransductionTheobromineConceptsCREB/BDNF pathwayBrain-derived neurotropic factorMedial prefrontal cortexCAMP response element-binding proteinBDNF pathwayTB ratsCN ratsNovel object recognition testPhosphorylated cAMP response element-binding proteinY-maze testMale Wistar ratsEffect of theobromineObject recognition testRadial arm maze taskEnzyme-linked immunosorbentPrimary methylxanthineBDNF levelsBDNF proteinNeurotropic factorNormal dietReal-time PCRWistar ratsDifferent brain processesElement-binding proteinP-CaMKII