1998
Stabilization of the Receptor Protein Tyrosine Phosphatase-Like Protein ICA512 in GH4C1 Cells upon Treatment with Estradiol, Insulin, and Epidermal Growth Factor*
Lee M, Dirkx R, Solimena M, Dannies P. Stabilization of the Receptor Protein Tyrosine Phosphatase-Like Protein ICA512 in GH4C1 Cells upon Treatment with Estradiol, Insulin, and Epidermal Growth Factor*. Endocrinology 1998, 139: 2727-2733. DOI: 10.1210/en.139.6.2727.Peer-Reviewed Original ResearchSecretory granule membranesEpidermal growth factorGTP-binding protein Rab3Granule membranesSecretory granule accumulationSecretory granule compartmentAssociated with secretory granule membranesTyrosine phosphatase-like proteinPhosphatase-like proteinGH4C1 cellsProlactin storageGH4C1 rat pituitary tumor cellsIncreased transcriptionPulse-chase procedureMature formRat pituitary tumor cellsSecretory granulesGranule compartmentGranule accumulationTreated cellsGrowth factorUntreated cellsPituitary tumor cellsMessenger RNAICA512
1994
Inhibition of rat prolactin (PRL) storage by coexpression of human PRL.
Arrandale J, Dannies P. Inhibition of rat prolactin (PRL) storage by coexpression of human PRL. Endocrinology 1994, 8: 1083-1090. PMID: 7997234, DOI: 10.1210/mend.8.8.7997234.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAsparagineBiological TransportCell CompartmentationCytoplasmic GranulesEpidermal Growth FactorEstradiolGene ExpressionHumansInsulinModels, MolecularPituitary NeoplasmsProlactinProtein ConformationRatsRecombinant Fusion ProteinsSerineSpecies SpecificityTransfectionTumor Cells, CulturedConceptsHuman PRLRat PRLGH4C1 cellsReceptor-mediated mechanismNM epidermal growth factorSecretory granulesNM estradiolDense-core secretory granulesEpidermal growth factorHormone treatmentPRL storageProlactin storagePRLGrowth factorNM insulinMore ratsUntransfected cellsRatsRegulated pathwayControl culturesCellsInhibitionMarked specificity
1984
ESTROGEN EFFECTS ON PROLACTIN STORAGE AND CELL GROWTH IN GH CELLS**Supported by United States Public Health Services Grant HD-11487.
DANNIES P, KIINO D, AMARA J. ESTROGEN EFFECTS ON PROLACTIN STORAGE AND CELL GROWTH IN GH CELLS**Supported by United States Public Health Services Grant HD-11487. 1984, 121-140. DOI: 10.1016/b978-0-12-490620-4.50014-x.Peer-Reviewed Original Research
1982
Hormonal regulation of prolactin storage in a clonal strain of rat pituitary tumor cells.
Kiino D, Dannies P. Hormonal regulation of prolactin storage in a clonal strain of rat pituitary tumor cells. The Yale Journal Of Biology And Medicine 1982, 55: 409-20. PMID: 6763814, PMCID: PMC2596570.Peer-Reviewed Original ResearchConceptsProlactin storageRat pituitary tumor cellsGH cellsPituitary tumor cellsPituitary functionNM estradiolTumor cellsProlactin synthesisEstradiol-induced increaseCells/NM insulinDays of treatmentProlactin-secreting cellsCell cycle distributionPercent increaseClonal strainsHormone secretionEpidermal growth factorPotassium depolarizationProlactin productionEstradiolHormone productionProlactinInsulinIntracellular prolactin