Effects of Thyrotropin-releasing Hormone and Hydrocortisone on Synthesis and Degradation of Prolactin in a Rat Pituitary Cell Strain
Dannies P, Tashjian A. Effects of Thyrotropin-releasing Hormone and Hydrocortisone on Synthesis and Degradation of Prolactin in a Rat Pituitary Cell Strain. Journal Of Biological Chemistry 1973, 248: 6174-6179. PMID: 4199262, DOI: 10.1016/s0021-9258(19)43524-2.Peer-Reviewed Original ResearchConceptsSynthesis of prolactinProlactin accumulationThyrotropin-releasing hormoneHydrocortisone resultsEffect of thyrotropinLong-term effectsPituitary cellsGH cellsProlactinDegradation of prolactinHormoneTerm effectsHydrocortisoneIntracellular poolDecreased accumulationClonal strainsCell strainsRadioactive leucineSpecific immunoprecipitationCellsHoursTreatmentDaysLeucineCulture medium