2022
End‐of‐life care quality for children with cancer who receive palliative care
Ananth P, Lindsay M, Nye R, Mun S, Feudtner C, Wolfe J. End‐of‐life care quality for children with cancer who receive palliative care. Pediatric Blood & Cancer 2022, 69: e29841. PMID: 35686746, PMCID: PMC10498672, DOI: 10.1002/pbc.29841.Peer-Reviewed Original ResearchConceptsIntensive care unit admissionCare unit admissionLife care qualityDistressing symptomsCancer decedentsEnd of lifeUnit admissionMechanical ventilationCare qualityPalliative Care DatabaseDays of lifeLower household incomeAnnual household incomeHospice enrollmentHospital admissionMultivariable analysisPatient factorsUnivariable analysisPalliative careCare databaseHospice servicesLower oddsResearch DatabaseCancer typesHospital services
2021
Sociodemographic and hospital‐based predictors of intense end‐of‐life care among children, adolescents, and young adults with hematologic malignancies
Mun S, Wang R, Ma X, Ananth P. Sociodemographic and hospital‐based predictors of intense end‐of‐life care among children, adolescents, and young adults with hematologic malignancies. Cancer 2021, 127: 3817-3824. PMID: 34185881, PMCID: PMC8478813, DOI: 10.1002/cncr.33764.Peer-Reviewed Original ResearchConceptsHematologic malignanciesYoung adultsLife careMultivariable logistic regression modelCancer-directed treatmentPremier Healthcare DatabaseRetrospective cohort studyEmergency department visitsIntensive care unitHigh-intensity endDays of lifeMajority of childrenLogistic regression modelsIntravenous chemotherapyTracheostomy placementCohort studyDepartment visitsCare unitMechanical ventilationHospital characteristicsMultivariable modelCardiopulmonary resuscitationType of insuranceHealthcare databasesMalignancy
2020
Patterns of medication use at end of life by pediatric inpatients with cancer
Prozora S, Shabanova V, Ananth P, Pashankar F, Kupfer GM, Massaro SA, Davidoff AJ. Patterns of medication use at end of life by pediatric inpatients with cancer. Pediatric Blood & Cancer 2020, 68: e28837. PMID: 33306281, DOI: 10.1002/pbc.28837.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChildChild, PreschoolFemaleHumansInfantInfant, NewbornInpatientsMaleNeoplasmsPalliative CareRetrospective StudiesTerminal CareYoung AdultConceptsMedication usePediatric inpatientsVizient Clinical Database/Resource ManagerHematopoietic stem cell transplantLife-sustaining medicationsMedication utilization patternsSymptom management medicationsUse of opioidsStem cell transplantIntensive care unitLength of stayAcademic medical centerResource use dataLast weekWarrants further studyEvidence-based approachVasopressor useEnd of lifeCare unitCell transplantMedication categoriesResuscitate statusRetrospective studyMalignancy typeOdds ratio
2017
Trends in Hospital Utilization and Costs among Pediatric Palliative Care Recipients
Ananth P, Melvin P, Berry JG, Wolfe J. Trends in Hospital Utilization and Costs among Pediatric Palliative Care Recipients. Journal Of Palliative Medicine 2017, 20: 946-953. PMID: 28453361, DOI: 10.1089/jpm.2016.0496.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChildDatabases, FactualEmergency Service, HospitalFemaleHospitalizationHumansMalePalliative CareRetrospective StudiesConceptsPediatric palliative carePPC consultationED visitsHospital admissionHospital costsHospital utilizationAnnual hospital admission rateIntensive care unit usePalliative care recipientsPercent of patientsRetrospective cohort studyAnnual ED visitsEmergency department visitsHospital admission ratesQuaternary children's hospitalYears of agePPC involvementCohort studyDepartment visitsMedian ageED useSingle centerChildren's HospitalPalliative careIll children
2016
Liposomal doxorubicin: Effective treatment for pediatric desmoid fibromatosis
Ananth P, Werger A, Voss S, Rodriguez‐Galindo C, Janeway KA. Liposomal doxorubicin: Effective treatment for pediatric desmoid fibromatosis. Pediatric Blood & Cancer 2016, 64: e26375. PMID: 27905688, DOI: 10.1002/pbc.26375.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAntibiotics, AntineoplasticChildChild, PreschoolDoxorubicinFemaleFibromatosis, AggressiveHumansMalePolyethylene GlycolsRetrospective StudiesConceptsProgression-free intervalLiposomal doxorubicinDesmoid fibromatosisLonger progression-free intervalMedian progression-free intervalRetrospective case seriesImportant treatment optionClinical responseMedical therapyCase seriesTumor sizeTreatment optionsEffective treatmentFibromatosisTreatmentChildrenMedications
2015
Hospital Use in the Last Year of Life for Children With Life-Threatening Complex Chronic Conditions
Ananth P, Melvin P, Feudtner C, Wolfe J, Berry JG. Hospital Use in the Last Year of Life for Children With Life-Threatening Complex Chronic Conditions. Pediatrics 2015, 136: 938-946. PMID: 26438707, PMCID: PMC4621793, DOI: 10.1542/peds.2015-0260.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChildChild, PreschoolChronic DiseaseCohort StudiesFemaleHealth Care CostsHospitalizationHumansInfantMaleRetrospective StudiesTerminal CareConceptsComplex chronic conditionsHospital useChronic conditionsPediatric Health Information System databaseHealth Information System databaseClinical Modification codesUS children's hospitalsHospital resource useCostly health careHealth care experiencesHematologic/Terminal admissionEnd of lifeUnderwent surgeryHospital daysHospital admissionImmunologic conditionsChildren's HospitalHospital costsInformation System databaseRetrospective analysisInternational ClassificationCare experiencesAdmissionHealth care