2007
Systematic review: opioid treatment for chronic back pain: prevalence, efficacy, and association with addiction.
Martell BA, O'Connor PG, Kerns RD, Becker WC, Morales KH, Kosten TR, Fiellin DA. Systematic review: opioid treatment for chronic back pain: prevalence, efficacy, and association with addiction. Annals Of Internal Medicine 2007, 146: 116-27. PMID: 17227935, DOI: 10.7326/0003-4819-146-2-200701160-00006.Peer-Reviewed Original ResearchConceptsChronic back painSubstance use disordersEfficacy of opioidsBack painMedication-taking behaviorUse disordersOpioid treatmentOpioid medicationsStudy qualityShort-term pain reliefCurrent substance use disorderCochrane Central RegisterLifetime substance use disorderControlled Clinical TrialsLong-term efficacyPoor study qualityEnglish-language studiesTransdermal opioidsOpioid prescribingPain reliefCentral RegisterDifferent opioidsReduced painClinical trialsNonsignificant reduction
2005
The prevalence and impact of alcohol problems in major depression: A systematic review
Sullivan LE, Fiellin DA, O’Connor P. The prevalence and impact of alcohol problems in major depression: A systematic review. The American Journal Of Medicine 2005, 118: 330-341. PMID: 15808128, DOI: 10.1016/j.amjmed.2005.01.007.Peer-Reviewed Original ResearchConceptsHealth care utilizationLifetime alcohol problemsCare utilizationDepression outcomesAlcohol problemsMajor depressionGeneral populationAlcohol abuseAlcohol dependenceHealth care utilization outcomesPrimary care outpatient settingCochrane Controlled Trials RegistryControlled Trials RegistrySocial functioningPsychiatric inpatient settingsCourse of depressionEnglish-language studiesSevere alcohol problemsTrials RegistryUtilization outcomesDepression courseOutpatient settingPrimary careDeath riskWorse outcomes
2002
The Health-Related Effects of Alcohol Use in Older Persons: A Systematic Review
Reid MC, Boutros NN, O'Connor PG, Cadariu A, Concato J. The Health-Related Effects of Alcohol Use in Older Persons: A Systematic Review. Substance Use & Addiction Journal 2002, 23: 149-164. DOI: 10.1023/a:1019896822588.Peer-Reviewed Original ResearchConceptsCause mortalityCognitive impairmentExposure statusFunctional disabilityAlcohol useOlder adultsFunctional impairmentMiddle-aged adult populationParticipants 60 yearsYears of ageEnglish-language studiesExposure-outcome associationsImportant confounding factorsHealth-related effectsEffects of alcoholMagnitude of riskCohort studySubstantial morbidityPercentage of studiesFormer drinkersProspective studyMean ageAlcohol exposureMethodologic qualityOutcome measuresThe Health–Related Effects of Alcohol Use in Older Persons: A Systematic Review
Reid M, Boutros N, O'Connor P, Cadariu A, Concato J. The Health–Related Effects of Alcohol Use in Older Persons: A Systematic Review. Substance Use & Addiction Journal 2002, 23: 149-164. PMID: 12444348, DOI: 10.1080/08897070209511485.Peer-Reviewed Original ResearchConceptsCause mortalityCognitive impairmentExposure statusFunctional disabilityAlcohol useOlder adultsFunctional impairmentMiddle-aged adult populationParticipants 60 yearsYears of ageEnglish-language studiesExposure-outcome associationsImportant confounding factorsHealth-related effectsEffects of alcoholMagnitude of riskCohort studySubstantial morbidityPercentage of studiesFormer drinkersProspective studyMean ageAlcohol exposureMethodologic qualityOutcome measures