2002
The Health-Related Effects of Alcohol Use in Older Persons: A Systematic Review
Reid MC, Boutros NN, O'Connor PG, Cadariu A, Concato J. The Health-Related Effects of Alcohol Use in Older Persons: A Systematic Review. Substance Use & Addiction Journal 2002, 23: 149-164. DOI: 10.1023/a:1019896822588.Peer-Reviewed Original ResearchConceptsCause mortalityCognitive impairmentExposure statusFunctional disabilityAlcohol useOlder adultsFunctional impairmentMiddle-aged adult populationParticipants 60 yearsYears of ageEnglish-language studiesExposure-outcome associationsImportant confounding factorsHealth-related effectsEffects of alcoholMagnitude of riskCohort studySubstantial morbidityPercentage of studiesFormer drinkersProspective studyMean ageAlcohol exposureMethodologic qualityOutcome measuresThe Health–Related Effects of Alcohol Use in Older Persons: A Systematic Review
Reid M, Boutros N, O'Connor P, Cadariu A, Concato J. The Health–Related Effects of Alcohol Use in Older Persons: A Systematic Review. Substance Use & Addiction Journal 2002, 23: 149-164. PMID: 12444348, DOI: 10.1080/08897070209511485.Peer-Reviewed Original ResearchConceptsCause mortalityCognitive impairmentExposure statusFunctional disabilityAlcohol useOlder adultsFunctional impairmentMiddle-aged adult populationParticipants 60 yearsYears of ageEnglish-language studiesExposure-outcome associationsImportant confounding factorsHealth-related effectsEffects of alcoholMagnitude of riskCohort studySubstantial morbidityPercentage of studiesFormer drinkersProspective studyMean ageAlcohol exposureMethodologic qualityOutcome measures
1997
Sustained-release methylphenidate for cognitive impairment in HIV-1- infected drug abusers: a pilot study
van Dyck CH, McMahon TJ, Rosen MI, O'Malley SS, O'Connor PG, Lin CH, Pearsall HR, Woods SW, Kosten TR. Sustained-release methylphenidate for cognitive impairment in HIV-1- infected drug abusers: a pilot study. Journal Of Neuropsychiatry 1997, 9: 29-36. PMID: 9017526, DOI: 10.1176/jnp.9.1.29.Peer-Reviewed Original ResearchMeSH KeywordsAdultAttentionCentral Nervous System StimulantsCognition DisordersDelayed-Action PreparationsDouble-Blind MethodFemaleHIV InfectionsHIV-1HumansLearningMaleMemoryMethylphenidateMiddle AgedNeuropsychological TestsOpioid-Related DisordersPilot ProjectsPsychomotor PerformanceSubstance-Related DisordersConceptsSustained-release methylphenidateCognitive impairmentDouble-blind placebo-controlled crossover trialPlacebo-controlled crossover trialComposite neuropsychological measuresImpaired neuropsychological test performanceClinical improvementPlacebo treatmentCrossover trialMethadone patientsNeuropsychological test performancePlacebo performancePsychostimulant drugsDrug abusersPatientsStudy designPilot studySubstance abusersImpairmentNeuropsychological measuresMethylphenidateMore improvementAbusersTreatmentTest performance
1992
Peptide T Treatment of Cognitive Impairment in HIV‐Positive Intravenous Drug Users
Rosen M, Bridge T, O'Malley S, Pearsall H, Martini B, O'Connor P, Brett‐Smith H, Thomas H, Van Dyck C, Woods S, Kosten T. Peptide T Treatment of Cognitive Impairment in HIV‐Positive Intravenous Drug Users. American Journal On Addictions 1992, 1: 332-338. DOI: 10.1111/j.1521-0391.1992.tb00359.x.Peer-Reviewed Original ResearchHIV-positive intravenous drug usersDouble-blind crossover studyPeptide T treatmentHIV-positive patientsPeptide TOpen clinical trialIntravenous drug usersVasoactive intestinal peptideAIDS dementiaCrossover studyNeuropsychological improvementAZT treatmentIntestinal peptideClinical trialsDrug usersCognitive impairmentPatientsNeuropsychological functionCognitive functionT treatmentPlaceboThree timesWeeksPotential utilityTreatment