2021
Performance of Platelet Mass Index as a Marker of Severity for Sepsis and Septic Shock in Children
Chegondi M, Vijayakumar N, Billa R, Badheka A, Karam O. Performance of Platelet Mass Index as a Marker of Severity for Sepsis and Septic Shock in Children. Journal Of Pediatric Intensive Care 2021, 12: 228-234. PMID: 37565022, PMCID: PMC10411082, DOI: 10.1055/s-0041-1731434.Peer-Reviewed Original ResearchPlatelet mass indexPediatric intensive care unitSeptic shockPICU admissionMass indexPrognostic indicatorFl/Day 1Marker of severityRetrospective observational studyIntensive care unitCare unitPediatric sepsisObservational studyClinical valueDay 3SepsisCharacteristic curveFurther studiesAdmissionPMI valuesChildrenAUCSpecificityNonsurvivorsBleeding in Critically Ill Children—Review of Literature, Knowledge Gaps, and Suggestions for Future Investigation
Aran AA, Karam O, Nellis ME. Bleeding in Critically Ill Children—Review of Literature, Knowledge Gaps, and Suggestions for Future Investigation. Frontiers In Pediatrics 2021, 9: 611680. PMID: 33585373, PMCID: PMC7873638, DOI: 10.3389/fped.2021.611680.Peer-Reviewed Original Research
2020
Brighter Days May Be Ahead: Continuous Measurement of Pediatric Intensive Care Unit Light and Sound
Greenfield KD, Karam O, O'Meara A. Brighter Days May Be Ahead: Continuous Measurement of Pediatric Intensive Care Unit Light and Sound. Frontiers In Pediatrics 2020, 8: 590715. PMID: 33194924, PMCID: PMC7649178, DOI: 10.3389/fped.2020.590715.Peer-Reviewed Original ResearchPediatric intensive care unitCourse of admissionIll childrenTertiary care pediatric intensive care unitProspective observational cohort studyPost-intensive care syndromeObservational cohort studyIntensive care unitModifiable environmental factorsMedian illuminancePatients 0Cardiovascular supportCohort studyCare unitClinical effectsPatientsMedian light levelsSleep/AdmissionSound levelsMedian sound levelChildrenUnit lightHoursLevelsAssociation Between Lactates, Blood Glucose, and Systemic Oxygen Delivery in Children After Cardiopulmonary Bypass
Klee P, Rimensberger PC, Karam O. Association Between Lactates, Blood Glucose, and Systemic Oxygen Delivery in Children After Cardiopulmonary Bypass. Frontiers In Pediatrics 2020, 8: 332. PMID: 32656170, PMCID: PMC7325592, DOI: 10.3389/fped.2020.00332.Peer-Reviewed Original ResearchPediatric critical care unitPICU admissionSystemic oxygen deliveryCardiopulmonary bypassCritical care unitsOxygen extractionBlood glucoseOxygen deliveryCardiac surgeryCare unitLow systemic oxygen deliveryObservational cohort studyDuration of bypassWorse clinical outcomesHigher oxygen extractionLogistic regression modelsCohort studyCardiac lesionsClinical outcomesSurrogate markerPyruvate ratioAdmissionHyperlactatemiaSame timepointsBypass
2016
Ketosis After Cardiopulmonary Bypass in Children Is Associated With an Inadequate Balance Between Oxygen Transport and Consumption*
Klee P, Arni D, Saudan S, Schwitzgebel VM, Sharma R, Karam O, Rimensberger PC. Ketosis After Cardiopulmonary Bypass in Children Is Associated With an Inadequate Balance Between Oxygen Transport and Consumption*. Pediatric Critical Care Medicine 2016, 17: 852-859. PMID: 27472253, DOI: 10.1097/pcc.0000000000000880.Peer-Reviewed Original ResearchConceptsIndependent risk factorPICU admissionCardiopulmonary bypassInsulin treatmentCardiac surgeryRisk factorsPostoperative blood glucose levelsProspective observational studyPatients 6 monthsSubset of patientsSubgroup of patientsVenous oxygen saturationTight glycemic controlBlood glucose levelsGlycemic controlTertiary PICUGlucose intakeWorse outcomesPatient outcomesHigh prevalenceObservational studyGlucose levelsOxygen saturationMetabolic constellationAdmission