p21(cip-1/waf-1) deficiency causes deformed nuclear architecture, centriole overduplication, polyploidy, and relaxed microtubule damage checkpoints in human hematopoietic cells.
Mantel C, Braun S, Reid S, Henegariu O, Liu L, Hangoc G, Broxmeyer H. p21(cip-1/waf-1) deficiency causes deformed nuclear architecture, centriole overduplication, polyploidy, and relaxed microtubule damage checkpoints in human hematopoietic cells. Blood 1999, 93: 1390-8. PMID: 9949183, DOI: 10.1182/blood.v93.4.1390.404k25_1390_1398.Peer-Reviewed Original ResearchCell CycleCell LineCell NucleusCentriolesCyclin-Dependent Kinase Inhibitor p21CyclinsHematopoiesisHematopoietic Stem CellsHumansMicrotubulesPolyploidyTumor Suppressor Protein p53