2015
Time to Chemotherapy After Abdominoperineal Resection: Comparison Between Primary Closure and Perineal Flap Reconstruction
Althumairi AA, Canner JK, Ahuja N, Sacks JM, Safar B, Efron JE. Time to Chemotherapy After Abdominoperineal Resection: Comparison Between Primary Closure and Perineal Flap Reconstruction. World Journal Of Surgery 2015, 40: 225-230. PMID: 26336877, DOI: 10.1007/s00268-015-3224-0.Peer-Reviewed Original ResearchConceptsFlap reconstruction groupAdjuvant chemotherapyFlap reconstructionPrimary closureAbdominoperineal resectionWound complicationsRectal adenocarcinomaReconstruction groupWound healingPerineal flap reconstructionPerineal wound complicationsPrimary closure groupPerineal wound closureLength of healingRetrospective reviewClosure groupChemotherapyPatientsPerineal defectsWound closureHealingResectionComplicationsAdenocarcinomaLength of time
2014
Clinicopathologic Presentation and Natural History of Anorectal Melanoma: A Case Series of 18 Patients
Hicks CW, Pappou EP, Magruder JT, Gazer B, Fang S, Wick EC, Gearhart SL, Ahuja N, Efron JE. Clinicopathologic Presentation and Natural History of Anorectal Melanoma: A Case Series of 18 Patients. JAMA Surgery 2014, 149: 608-611. PMID: 24848283, DOI: 10.1001/jamasurg.2013.4643.Peer-Reviewed Original ResearchConceptsAnorectal melanomaOverall disease-specific mortalityNatural historyDisease-specific mortalityDisease-specific survivalNonspecific presenting symptomsWide local excisionRare malignant neoplasmVariable natural historyNonspecific presentationPresenting symptomAbdominoperineal resectionLocal excisionCase seriesMedian timeSurgical managementRectal lesionsMalignant neoplasmsPrognostic parametersClinicopathologic presentationLate diagnosisAdvanced stageIncorrect diagnosisSmall lesionsLarger study