2024
Endovascular Treatment of Patients With Acute Ischemic Stroke With Tandem Lesions Presenting With Low Alberta Stroke Program Early Computed Tomography Score.
Galecio-Castillo M, Farooqui M, Guerrero W, Ribo M, Hassan A, Jumaa M, Divani A, Abraham M, Petersen N, Fifi J, Malik A, Siegler J, Nguyen T, Sheth S, Linares G, Janjua N, Soomro J, Quispe-Orozco D, Olivé-Gadea M, Tekle W, Zaidi S, Sabbagh S, Barkley T, Prasad A, De Leacy R, Abdalkader M, Salazar-Marioni S, Gordon W, Turabova C, Rodriguez-Calienes A, Dibas M, Mokin M, Yavagal D, Yoo A, Sarraj A, Jovin T, Ortega-Gutierrez S. Endovascular Treatment of Patients With Acute Ischemic Stroke With Tandem Lesions Presenting With Low Alberta Stroke Program Early Computed Tomography Score. Journal Of The American Heart Association 2024, 13: e035977. PMID: 39508172, DOI: 10.1161/jaha.124.035977.Peer-Reviewed Original ResearchLower Alberta Stroke Program Early Computed Tomography ScoreAlberta Stroke Program Early Computed Tomography ScoreModified Rankin ScaleComputed Tomography ScoreSymptomatic intracranial hemorrhageEndovascular thrombectomyIntracranial hemorrhageTandem lesionsBaseline Alberta Stroke Program Early Computed Tomography ScoreAnterior circulation tandem lesionsModified Rankin Scale shiftModified Rankin Scale 0 to 2Score 0 to 2Safety of endovascular thrombectomySymptomatic intracranial hemorrhage riskOdds of symptomatic intracranial hemorrhageEndovascular treatment of patientsAcute large-vessel occlusionInternal carotid artery stenosis/occlusionIntracranial hemorrhage riskRetrospective analysis of dataProportion of patientsTreatment of patientsOrdinal modified Rankin ScaleAssociated with reduced oddsCervical Dissection in Patients With Tandem Lesions Is Associated With Distal Embolism and Lower Recanalization Success
Galecio-Castillo M, Guerrero W, Hassan A, Farooqui M, Jumaa M, Divani A, Abraham M, Petersen N, Fifi J, Malik A, Siegler J, Nguyen T, Sheth S, Yoo A, Linares G, Janjua N, Quispe-Orozco D, Olivé-Gadea M, Tekle W, Zaidi S, Sabbagh S, Barkley T, Prasad A, De Leacy R, Abdalkader M, Salazar-Marioni S, Soomro J, Gordon W, Turabova C, Rodriguez-Calienes A, Dibas M, Mokin M, Yavagal D, Ribo M, Jovin T, Ortega-Gutierrez S. Cervical Dissection in Patients With Tandem Lesions Is Associated With Distal Embolism and Lower Recanalization Success. Stroke 2024, 55: 1808-1817. PMID: 38913799, DOI: 10.1161/strokeaha.123.046148.Peer-Reviewed Original ResearchConceptsInternal carotid arteryCervical internal carotid arteryDistal embolizationModified ThrombolysisTandem lesionsMulticenter retrospective cohort studyParenchymal hematoma type 2Internal carotid artery stenosis/occlusionModified Rankin Scale scoreSymptomatic intracranial hemorrhageInverse probability of treatment weightingCerebral Infarction scoreCervical ICA dissectionRetrospective cohort studyProbability of treatment weightingRankin Scale scoreAssociated with higher ratesFunctional independenceRates of hypertensionAssociated with distal embolizationSelf-expanding stentsDissection etiologyRisk of distal embolizationICA occlusionCervical dissectionDeviation From Personalized Blood Pressure Targets Correlates With Worse Outcome After Successful Recanalization
Zhang Z, Pu Y, Yu L, Bai H, Duan W, Liu X, Nie X, Wen Z, Zheng L, Hu X, Leng X, Pan Y, Petersen N, Liu L. Deviation From Personalized Blood Pressure Targets Correlates With Worse Outcome After Successful Recanalization. Journal Of The American Heart Association 2024, 13: e033633. PMID: 38533955, PMCID: PMC11179781, DOI: 10.1161/jaha.123.033633.Peer-Reviewed Original ResearchConceptsBlood pressure targetsBlood pressureAutoregulatory limitsWorse outcomesAssociated with symptomatic intracranial hemorrhageAssociated with unfavorable clinical outcomesPressure targetsAssociated with worse outcomesAssociated with poor outcomesSignificant infarction growthSymptomatic intracranial hemorrhageUnfavorable clinical outcomeLarge vessel occlusion strokeAcute ischemic strokeMean velocity indexIntracranial hemorrhageBP management strategiesNeurological deteriorationClinical outcomesInfarct growthPoor outcomeEndovascular thrombectomyOcclusion strokeRecanalizationIschemic strokeAnesthetic management for large vessel occlusion acute ischemic stroke with tandem lesions
Farooqui M, Galecio-Castillo M, Hassan A, Divani A, Jumaa M, Ribo M, Petersen N, Abraham M, Fifi J, Guerrero W, Malik A, Siegler J, Nguyen T, Sheth S, Yoo A, Linares G, Janjua N, Quispe-Orozco D, Tekle W, Sabbagh S, Zaidi S, Gadea M, Prasad A, Qureshi A, De Leacy R, Abdalkader M, Salazar-Marioni S, Soomro J, Gordon W, Turabova C, Rodriguez-Calienes A, Vivanco-Suarez J, Mokin M, Yavagal D, Jovin T, Ortega-Gutierrez S. Anesthetic management for large vessel occlusion acute ischemic stroke with tandem lesions. Journal Of NeuroInterventional Surgery 2024, jnis-2023-021360. PMID: 38429099, DOI: 10.1136/jnis-2023-021360.Peer-Reviewed Original ResearchSymptomatic intracranial hemorrhageModified Rankin scoreFavorable functional outcomeAlberta Stroke Program Early CT ScoreNational Institutes of Health Stroke ScaleEndovascular therapyInternal carotid arteryFunctional outcomesAcute ischemic strokeProcedural sedationExcellent recanalizationTandem lesionsAssociated with superior functional outcomesBaseline Alberta Stroke Program Early CT ScoreAnesthetic strategyRecanalization timeAnterior circulation tandem lesionsGeneral anesthesiaAnesthetic techniqueDegree of internal carotid arteryInternal carotid artery stentingOptimal anesthetic strategyIschemic strokeLarge vessel occlusion acute ischemic strokeAcute ischemic stroke patients
2023
Endovascular treatment of acute ischemic stroke patients with tandem lesions: antegrade versus retrograde approach.
Galecio-Castillo M, Abraham M, Farooqui M, Hassan A, Divani A, Jumaa M, Ribo M, Petersen N, Fifi J, Guerrero W, Malik A, Siegler J, Nguyen T, Sheth S, Yoo A, Linares G, Janjua N, Quispe-Orozco D, Qureshi A, Tekle W, Ikram A, Zaidi S, Zevallos C, Taborda B, Devarajan A, Zhang L, Abdalkader M, Salazar-Marioni S, Soomro J, Gordon W, Rodriguez-Calienes A, Vivanco-Suarez J, Woolfolk K, Mokin M, Yavagal D, Ortega-Gutierrez S. Endovascular treatment of acute ischemic stroke patients with tandem lesions: antegrade versus retrograde approach. Journal Of Neurosurgery 2023, 140: 1726-1735. PMID: 38157542, PMCID: PMC11271811, DOI: 10.3171/2023.10.jns231702.Peer-Reviewed Original ResearchConceptsSymptomatic intracranial hemorrhageFirst-pass effectExcellent recanalizationRetrograde approachMRS scoreRecanalization timePuncture to recanalization timeTreatment of acute ischemic stroke patientsTandem lesionsAcute ischemic stroke patientsMRS score 0Acute ischemic strokeIschemic stroke patientsAntegrade groupIntracranial hemorrhageEndovascular treatmentMulticenter studyGroin punctureSafety profileEndovascular therapyAcute stentingProcedural outcomesScore 0Ordinal shiftTL patientsSafety Outcomes of Antiplatelet Therapy During Endovascular Treatment of Tandem Lesions in Acute Ischemic Stroke Patients
Farooqui M, Divani A, Galecio-Castillo M, Hassan A, Jumaa M, Ribo M, Abraham M, Petersen N, Fifi J, Guerrero W, Malik A, Siegler J, Nguyen T, Sheth S, Yoo A, Linares G, Janjua N, Quispe-Orozco D, Ikram A, Tekle W, Zaidi S, Zevallos C, Rizzo F, Barkley T, De Leacy R, Khalife J, Abdalkader M, Salazar-Marioni S, Soomro J, Gordon W, Rodriguez-Calienes A, Vivanco-Suarez J, Turabova C, Mokin M, Yavagal D, Ortega-Gutierrez S. Safety Outcomes of Antiplatelet Therapy During Endovascular Treatment of Tandem Lesions in Acute Ischemic Stroke Patients. Translational Stroke Research 2023, 1-11. PMID: 38017258, PMCID: PMC11271812, DOI: 10.1007/s12975-023-01214-9.Peer-Reviewed Original ResearchSymptomatic intracranial hemorrhageEndovascular therapyIn-stent thrombosisTandem lesionsAnterior circulation tandem lesionsRate of symptomatic hemorrhageFavorable functional statusTreatment of tandem lesionsRisk of hemorrhageAcute ischemic stroke patientsNo significant associationExcellent reperfusionIschemic stroke patientsSymptomatic hemorrhageMRS 0Intracranial hemorrhageAntiplatelet strategiesEndovascular treatmentMulticenter studyAntiplatelet therapyAntiplatelet medicationsAntiplatelet regimensMTICI 2c/3Carotid stentingPrimary outcomeAssociation between blood pressure variability and outcomes after endovascular thrombectomy for acute ischemic stroke: An individual patient data meta-analysis
Palaiodimou L, Joundi R, Katsanos A, Ahmed N, Kim J, Goyal N, Maier I, de Havenon A, Anadani M, Matusevicius M, Mistry E, Khatri P, Arthur A, Sarraj A, Yaghi S, Shoamanesh A, Catanese L, Psychogios M, Malhotra K, Spiotta A, Vassilopoulou S, Tsioufis K, Sandset E, Alexandrov A, Petersen N, Tsivgoulis G. Association between blood pressure variability and outcomes after endovascular thrombectomy for acute ischemic stroke: An individual patient data meta-analysis. European Stroke Journal 2023, 9: 88-96. PMID: 37921233, PMCID: PMC10916831, DOI: 10.1177/23969873231211157.Peer-Reviewed Original ResearchBlood pressure variabilitySymptomatic intracranial hemorrhageAcute ischemic strokeEndovascular thrombectomyFunctional impairmentIschemic strokeHighest tertileAIS patientsPressure variabilityIndividual BP measurementsMean BP levelsDiastolic BP levelsIndividual patient dataLogistic mixed-effects modelsSBP-CVSBP-SDIntravenous thrombolysisStroke outcomeStroke severitySuccessful recanalizationBP levelsIntracranial hemorrhageBP measurementsHigh mortalityTertileSafety of Intravenous Cangrelor Versus Dual Oral Antiplatelet Loading Therapy in Endovascular Treatment of Tandem Lesions: An Observational Cohort Study
Rodriguez‐Calienes A, Oliver M, Hassan A, Vivanco‐Suarez J, Divani A, Ribo M, Petersen N, Abraham M, Fifi J, Guerrero W, Malik A, Siegler J, Nguyen T, Sheth S, Yoo A, Linares G, Janjua N, Quispe‐Orozco D, Galecio‐Castillo M, Alhajala H, Malaga M, Farooqui M, Jovin T, Jumaa M, Ortega‐Gutierrez S. Safety of Intravenous Cangrelor Versus Dual Oral Antiplatelet Loading Therapy in Endovascular Treatment of Tandem Lesions: An Observational Cohort Study. Stroke Vascular And Interventional Neurology 2023, 3 DOI: 10.1161/svin.123.001020.Peer-Reviewed Original ResearchSymptomatic intracranial hemorrhageIntravenous cangrelorIntracranial hemorrhageStent thrombosisSafety profilePetechial hemorrhagesTandem lesionsType 2Parenchymal hematoma type 2Inverse probabilityInternational multicenter cohortSimilar safety profileAcute ischemic strokeObservational cohort studyMyocardial infarction protocolDAPT regimensIntraprocedural administrationLoading therapyAntiplatelet therapyCohort studyIschemic strokeLesion interventionMulticenter cohortEndovascular treatmentInfarction protocolsLow dose intravenous cangrelor versus glycoprotein IIb/IIIa inhibitors in endovascular treatment of tandem lesions
Jumaa M, Rodriguez-Calienes A, Dawod G, Vivanco-Suarez J, Hassan A, Divani A, Oliver M, Ribo M, Petersen N, Abraham M, Fifi J, Guerrero W, Malik A, Siegler J, Nguyen T, Sheth S, Yoo A, Linares G, Janjua N, Quispe-Orozco D, Galecio-Castillo M, Zevallos C, Malaga M, Farooqui M, Jovin T, Zaidi S, Ortega-Gutierrez S. Low dose intravenous cangrelor versus glycoprotein IIb/IIIa inhibitors in endovascular treatment of tandem lesions. Journal Of Stroke And Cerebrovascular Diseases 2023, 32: 107438. PMID: 37883826, PMCID: PMC11271813, DOI: 10.1016/j.jstrokecerebrovasdis.2023.107438.Peer-Reviewed Original ResearchConceptsSymptomatic intracranial hemorrhageGP IIb/IIIa inhibitorsRate of symptomatic intracranial hemorrhageGP IIb/IIIaAntiplatelet therapyMechanical thrombectomyRetrospective non-randomized cohort studyGP IIb/IIIa inhibitor groupHemorrhagic infarction type 1Tandem lesionsComplete reperfusionType 1Periprocedural antiplatelet therapyReducing hemorrhage ratesParenchymal hematoma type 1Treatment of tandem lesionsNon-randomized cohort studyAcute carotid stentingIntravenous (IVGlycoprotein IIb/IIIa inhibitorsRate of complete reperfusionAssociated with increased oddsCangrelor groupHemorrhage rateIntravenous cangrelorMechanical thrombectomy beyond 24 hours from last known well in tandem lesions: A multicenter cohort study.
Rodriguez-Calienes A, Hassan A, Siegler J, Galecio-Castillo M, Farooqui M, Jumaa M, Janjua N, Divani A, Ribo M, Abraham M, Petersen N, Fifi J, Guerrero W, Malik A, Nguyen T, Sheth S, Yoo A, Linares G, Lu Y, Vivanco-Suarez J, Ortega-Gutierrez S. Mechanical thrombectomy beyond 24 hours from last known well in tandem lesions: A multicenter cohort study. Interventional Neuroradiology 2023, 15910199231196960. PMID: 37642978, DOI: 10.1177/15910199231196960.Peer-Reviewed Original ResearchSymptomatic intracranial hemorrhageNIH Stroke ScaleMechanical thrombectomyHospital mortalityComplete reperfusionTandem lesionsFunctional independenceAnterior circulation tandem lesionsEffectiveness of MTMulticenter cohort studyLarge vessel occlusionFuture prospective studiesTreatment of patientsOutcomes of interestMulticenter registryStroke ScaleCohort studyIntracranial hemorrhageProspective studyVessel occlusionHematoma 2Treatment weightingPatientsInverse probabilityMortalityClinical and Safety Outcomes of Endovascular Therapy 6 to 24 Hours After Large Vessel Occlusion Ischemic Stroke With Tandem Lesions
Galecio-Castillo M, Farooqui M, Hassan A, Jumaa M, Divani A, Ribo M, Abraham M, Petersen N, Fifi J, Guerrero W, Malik A, Siegler J, Nguyen T, Sheth S, Yoo A, Linares G, Janjua N, Quispe-Orozco D, Tekle W, Zaidi S, Sabbagh S, Olivé-Gadea M, Barkley T, De Leacy R, Sprankle K, Abdalkader M, Salazar-Marioni S, Soomro J, Gordon W, Turabova C, Vivanco-Suarez J, Rodriguez-Calienes A, Mokin M, Yavagal D, Jovin T, Ortega-Gutierrez S. Clinical and Safety Outcomes of Endovascular Therapy 6 to 24 Hours After Large Vessel Occlusion Ischemic Stroke With Tandem Lesions. Journal Of Stroke 2023, 25: 378-387. PMID: 37607694, PMCID: PMC10574302, DOI: 10.5853/jos.2023.00759.Peer-Reviewed Original ResearchSymptomatic intracranial hemorrhageSafety outcomesMRS 0Secondary outcomesEndovascular therapyTandem lesionsLarge vessel occlusion ischemic strokeLower median National InstitutesHealth Stroke Scale scoreLarge vessel occlusion patientsEarly neurological improvementMedian National InstitutesStroke Scale scoreAlberta Stroke ProgramModified Rankin ScaleFirst-pass effectEarly windowIntravenous thrombolysisOrdinal mRSNeurological improvementSuccessful reperfusionTomography ScoreIschemic strokeRankin ScaleStroke ProgramSafety Outcomes of Mechanical Thrombectomy Versus Combined Thrombectomy and Intravenous Thrombolysis in Tandem Lesions
Rodriguez-Calienes A, Galecio-Castillo M, Farooqui M, Hassan A, Jumaa M, Divani A, Ribo M, Abraham M, Petersen N, Fifi J, Guerrero W, Malik A, Siegler J, Nguyen T, Yoo A, Linares G, Janjua N, Quispe-Orozco D, Tekle W, Alhajala H, Ikram A, Rizzo F, Qureshi A, Begunova L, Matsoukas S, Vigilante N, Salazar-Marioni S, Abdalkader M, Gordon W, Soomro J, Turabova C, Vivanco-Suarez J, Mokin M, Yavagal D, Jovin T, Sheth S, Ortega-Gutierrez S. Safety Outcomes of Mechanical Thrombectomy Versus Combined Thrombectomy and Intravenous Thrombolysis in Tandem Lesions. Stroke 2023, 54: 2522-2533. PMID: 37602387, PMCID: PMC10599264, DOI: 10.1161/strokeaha.123.042966.Peer-Reviewed Original ResearchConceptsRisk of sICHParenchymal hematoma type 2Symptomatic intracranial hemorrhageRankin Scale score 0Intravenous antiplatelet therapyIntravenous thrombolysisFavorable functional outcomeMechanical thrombectomyHemorrhagic transformationFunctional outcomeType 2Antiplatelet therapyHospital mortalitySuccessful reperfusionComplete reperfusionScore 0Tandem lesionsAnterior circulation tandem lesionsExcellent functional outcomeIVT treatmentStroke centersMulticenter cohortPrimary outcomeRevascularization techniquesAlone groupFunctional and Safety Outcomes of Carotid Artery Stenting and Mechanical Thrombectomy for Large Vessel Occlusion Ischemic Stroke With Tandem Lesions
Farooqui M, Zaidat O, Hassan A, Quispe-Orozco D, Petersen N, Divani A, Ribo M, Abraham M, Fifi J, Guerrero W, Malik A, Siegler J, Nguyen T, Sheth S, Yoo A, Linares G, Janjua N, Galecio-Castillo M, Tekle W, Ringheanu V, Oliver M, Dawod G, Kobsa J, Prasad A, Ikram A, Lin E, Below K, Zevallos C, Gadea M, Qureshi A, Dajles A, Matsoukas S, Rana A, Abdalkader M, Salazar-Marioni S, Soomro J, Gordon W, Vivanco-Suarez J, Turabova C, Mokin M, Yavagal D, Jumaa M, Ortega-Gutierrez S. Functional and Safety Outcomes of Carotid Artery Stenting and Mechanical Thrombectomy for Large Vessel Occlusion Ischemic Stroke With Tandem Lesions. JAMA Network Open 2023, 6: e230736. PMID: 36857054, PMCID: PMC9978940, DOI: 10.1001/jamanetworkopen.2023.0736.Peer-Reviewed Original ResearchConceptsSymptomatic intracranial hemorrhageCarotid artery stenting groupCarotid artery stentingLarge vessel occlusionNonstented groupDigital subtraction angiographyModified Rankin ScaleMechanical thrombectomyFunctional outcomesCross-sectional studyCervical lesionsSafety outcomesTandem lesionsMRS scoreSubtraction angiographyOdds of favorable functional outcomeIncreased risk of sICHArtery stentingAnterior circulation tandem lesionsDegree of cervical stenosisRisk of symptomatic intracranial hemorrhageOutcomes of carotid artery stentingCervical internal carotid arteryOdds of symptomatic intracranial hemorrhageInternal carotid artery stenosis