2022
The protective effect of rs373863828 on type 2 diabetes does not operate through a body composition pathway in adult Samoans
Hawley NL, Duckham RL, Carlson JC, Naseri T, Reupena MS, Lameko V, Pomer A, Wetzel A, Selu M, Lupematisila V, Unasa F, Vesi L, Fatu T, Unasa S, Faasalele‐Savusa K, Rivara AC, Russell E, Delany JP, Viali S, Kershaw EE, Minster RL, Weeks DE, McGarvey ST. The protective effect of rs373863828 on type 2 diabetes does not operate through a body composition pathway in adult Samoans. Obesity 2022, 30: 2468-2476. PMID: 36284436, PMCID: PMC10111239, DOI: 10.1002/oby.23559.Peer-Reviewed Original ResearchConceptsFat-free massType 2 diabetesFat distributionProtective effectBody compositionFavorable body fat distributionDual-energy X-ray absorptiometry-derived body compositionBody fat distributionGreater fat-free massPercent body fatBody size/compositionAssociation of genotypesRs373863828 genotypeVisceral adiposityHigher BMIAdult SamoansRole of fatGreater BMILean massBody fatLower oddsParadoxical associationTissue-specific mechanismsA alleleDiabetes
2021
1108-P: Care Cascade Engagement and Characteristics of Diabetes Awareness in Adult Samoans in 2010 and 2018
RIVARA A, RUSSELL E, VIALI S, REUPENA M, NASERI T, POMER A, MINSTER R, WEEKS D, MCGARVEY S, HAWLEY N. 1108-P: Care Cascade Engagement and Characteristics of Diabetes Awareness in Adult Samoans in 2010 and 2018. Diabetes 2021, 70 DOI: 10.2337/db21-1108-p.Peer-Reviewed Original ResearchGlycemic controlMedication useDiabetes awarenessAdult SamoansUnmet needSocioeconomic positionCare cascadeLifestyle scoreDiabetes prevalenceHigher BMICare engagementDiabetes careHigher oddsDisease awarenessLower oddsGreater oddsLogistic regressionDiabetesDoctor's diagnosisTime pointsNational InstituteOddsGenetic variantsDiagnosisCare