2001
Effect of Tryptophan Depletion on Alcohol Cue‐Induced Craving in Abstinent Alcoholic Patients
Petrakis I, Trevisan L, Boutros N, Limoncelli D, Cooney N, Krystal J. Effect of Tryptophan Depletion on Alcohol Cue‐Induced Craving in Abstinent Alcoholic Patients. Alcohol Clinical And Experimental Research 2001, 25: 1151-1155. PMID: 11505046, DOI: 10.1111/j.1530-0277.2001.tb02329.x.Peer-Reviewed Original ResearchConceptsCue-induced cravingAlcohol-dependent patientsTryptophan depletionAlcohol cue-induced cravingDouble-blind fashionPlasma free tryptophanAbstinent alcoholic patientsAmino acid drinkActive tryptophan depletionAlcoholic patientsSerotonin synthesisAcid drinkSober alcoholicsAlcoholic individualsPrecursor tryptophanCue exposurePatientsAlcohol useAbstinent alcoholic individualsCravingFree tryptophanAlcohol cuesTest dayGreater increaseSimilar drinks
1998
Compliance with Treatment and Follow‐up Protocols in Project MATCH: Predictors and Relationship to Outcome
Mattson M, Del Boca F, Carroll K, Cooney N, DiClemente C, Donovan D, Kadden R, McRee B, Rice C, Rycharik R, Zweben A. Compliance with Treatment and Follow‐up Protocols in Project MATCH: Predictors and Relationship to Outcome. Alcohol Clinical And Experimental Research 1998, 22: 1328-1339. PMID: 9756050, DOI: 10.1111/j.1530-0277.1998.tb03916.x.Peer-Reviewed Original ResearchConceptsStrongest baseline predictorsMultisite clinical trialProject MATCHClinicians/investigatorsPatient-treatment matchingTreatment complianceClinical trialsBaseline predictorsDrinking outcomesTherapy sessionsTreatment deliveryResearch protocolTreatment environmentFollowHigh rateTreatmentFuture studiesResearch followCompliancePredictorsAttendance dataPrevious studiesPatientsTherapyTrialsCompliance with Treatment and Follow-up Protocols in Project MATCH
Mattson M, Del Boca F, Carroll K, Cooney N, DiClemente C, Donovan D, Kadden R, McRee B, Rice C, Rycharik R, Zweben A. Compliance with Treatment and Follow-up Protocols in Project MATCH. Alcohol Clinical And Experimental Research 1998, 22: 1328. DOI: 10.1097/00000374-199809000-00020.Peer-Reviewed Original ResearchStrongest baseline predictorsMultisite clinical trialProject MATCHClinicians/investigatorsPatient-treatment matchingTreatment complianceClinical trialsBaseline predictorsDrinking outcomesTherapy sessionsTreatment deliveryResearch protocolTreatment environmentFollowHigh rateTreatmentFuture studiesResearch followComplianceAttendance dataPrevious studiesPatientsTherapyTrialsTreatment integrity
1996
Serotonergic and noradrenergic dysregulation in alcoholism: m- chlorophenylpiperazine and yohimbine effects in recently detoxified alcoholics and healthy comparison subjects
Krystal JH, Webb E, Cooney NL, Kranzler HR, Southwick SW, Heninger GR, Charney DS. Serotonergic and noradrenergic dysregulation in alcoholism: m- chlorophenylpiperazine and yohimbine effects in recently detoxified alcoholics and healthy comparison subjects. American Journal Of Psychiatry 1996, 153: 83-92. PMID: 8540598, DOI: 10.1176/ajp.153.1.83.Peer-Reviewed Original ResearchConceptsHealthy comparison subjectsAlcoholic patientsComparison subjectsCortisol responseYohimbine infusionPostsynaptic noradrenergic receptorsBlood pressure responseDouble-blind conditionsNoradrenergic reactivitySaline placeboNoradrenergic receptorsMHPG levelsIntravenous infusionYohimbine effectMHPG responsePlasma levelsNoradrenergic systemPersistent alterationsNoradrenergic dysregulationMale inpatientsDrug effectsNeuroendocrine responsivityPatientsPhysiologic responsesPlasma cortisol
1995
Differences between responders and nonresponders to cocaine cues in the laboratory
Avants S, Margolin A, Kosten T, Cooney N. Differences between responders and nonresponders to cocaine cues in the laboratory. Addictive Behaviors 1995, 20: 215-224. PMID: 7484315, DOI: 10.1016/0306-4603(94)00066-2.Peer-Reviewed Original ResearchConceptsDrug cuesGroup differencesDrug-dependent subjectsCocaine-dependent methadone patientsGroups of subjectsMethadone patientsCocaine cravingCocaine dependenceCocaine expectanciesCocaine aversionNonrespondersOne-thirdRespondersCue responsesCravingDemographic variablesSubjectsCurrent studyPatientsDifferences
1992
Relationship between role-play measures of coping skills and alcoholism treatment outcome
Kadden R, Litt M, Cooney N, Busher D. Relationship between role-play measures of coping skills and alcoholism treatment outcome. Addictive Behaviors 1992, 17: 425-437. PMID: 1332433, DOI: 10.1016/0306-4603(92)90003-e.Peer-Reviewed Original ResearchConceptsTreatment outcomesInteractional therapyAlcoholism treatment outcomeBetter drinking outcomesType of treatmentEffect of treatmentPatient-treatment matchingSelf-reported urgePatient characteristicsObserver-rated anxietyAftercare treatmentTreatment typeHeavy drinkingAlcoholic clientsDrinking outcomesGroup treatmentOutcomesTreatmentPatientsTherapyRole-play measureRole-play scenesRole-play testMore difficulty
1991
Matching Alcoholics to Coping Skills or Interactional Therapies: Two-Year Follow-Up Results
Cooney N, Kadden R, Litt M, Getter H. Matching Alcoholics to Coping Skills or Interactional Therapies: Two-Year Follow-Up Results. Journal Of Consulting And Clinical Psychology 1991, 59: 598-601. PMID: 1655847, DOI: 10.1037/0022-006x.59.4.598.Peer-Reviewed Original ResearchConceptsBetter outcomesCognitive impairmentSkills treatmentInpatient alcoholism treatment programInteractional therapyTwo-year followAlcoholism treatment programInteractional treatmentUp ResultsOutcome dataSurvival analysisGlobal psychopathologyTreatment programPatientsGroup treatmentTreatmentTherapyCoping skillsOutcomesImpairmentSkills trainingFollowAlcoholics
1986
A Validation Study of Four Scales Measuring Severity of Alcohol Dependence
COONEY N, MEYER R, KAPLAN R, BAKER L. A Validation Study of Four Scales Measuring Severity of Alcohol Dependence. Addiction 1986, 81: 223-229. PMID: 3458490, DOI: 10.1111/j.1360-0443.1986.tb00320.x.Peer-Reviewed Original ResearchConceptsDependence ScaleAlcohol consumptionDependence QuestionnaireDependence scoresInpatient alcohol rehabilitation programAlcohol rehabilitation programAlcohol Dependence QuestionnairePost-treatment abstinenceDetoxification medicationAlcoholic patientsWithdrawal ScaleRehabilitation programAlcohol dependenceSignificant positive correlationHigh convergent validityHeavy drinkingConstruct of dependenceImpaired controlDependence severityLast monthSeverityPatientsConvergent validityPsychological problemsScores