2013
Identification of a New Stromal Cell Type Involved in the Regulation of Inflamed B Cell Follicles
Mionnet C, Mondor I, Jorquera A, Loosveld M, Maurizio J, Arcangeli ML, Ruddle NH, Nowak J, Aurrand-Lions M, Luche H, Bajénoff M. Identification of a New Stromal Cell Type Involved in the Regulation of Inflamed B Cell Follicles. PLOS Biology 2013, 11: e1001672. PMID: 24130458, PMCID: PMC3794863, DOI: 10.1371/journal.pbio.1001672.Peer-Reviewed Original ResearchConceptsStromal cell typesB cell folliclesT cell zonesCell typesFate-mapping systemStromal cellsCellular demandB cellsLymph Node Stromal CellsSurvival signalsStromal cell subsetsB cell ablationLN stromal cellsCell zoneAdhesive substrataCell ablationCell subsetsImmune responseCellsFolliclesInflammationSubstrataRegulationTransient boundaryLymphocytes
1971
Experimental autoallergic encephalomyelitis and cellular hypersensitivity in vitro.
Ellison G, Waksman B, Ruddle N. Experimental autoallergic encephalomyelitis and cellular hypersensitivity in vitro. Neurology 1971, 21: 778-82. PMID: 5106293, DOI: 10.1212/wnl.21.8.778.Peer-Reviewed Original Research
1968
CYTOTOXICITY MEDIATED BY SOLUBLE ANTIGEN AND LYMPHOCYTES IN DELAYED HYPERSENSITIVITY
Ruddle N, Waksman B. CYTOTOXICITY MEDIATED BY SOLUBLE ANTIGEN AND LYMPHOCYTES IN DELAYED HYPERSENSITIVITY. Journal Of Experimental Medicine 1968, 128: 1237-1254. PMID: 4176937, PMCID: PMC2138572, DOI: 10.1084/jem.128.6.1237.Peer-Reviewed Original ResearchConceptsLymph node cellsTarget cell ratiosDelayed hypersensitivityNode cellsSoluble antigenSpecific antigenBovine gammaglobulinProgressive destructionCell ratioAntigen concentrationTarget cellsLymphocytesAntigenHypersensitivityCell enumerationEgg albuminCellsHrRat embryo fibroblastsTissue cultureLymphGammaglobulinRatsEmbryo fibroblastsCYTOTOXICITY MEDIATED BY SOLUBLE ANTIGEN AND LYMPHOCYTES IN DELAYED HYPERSENSITIVITY
Ruddle N, Waksman B. CYTOTOXICITY MEDIATED BY SOLUBLE ANTIGEN AND LYMPHOCYTES IN DELAYED HYPERSENSITIVITY. Journal Of Experimental Medicine 1968, 128: 1255-1265. PMID: 4235040, PMCID: PMC2138586, DOI: 10.1084/jem.128.6.1255.Peer-Reviewed Original ResearchConceptsLymph node cellsNode cellsSensitized lymph node cellsArthus reactivityLewis ratsBN ratsSkin reactivityAllogeneic fibroblastsDelayed hypersensitivitySoluble antigenSpecific antigenHomologous conjugateCytotoxic effectsRatsAntigenHypersensitivityProtein carrierHuman serum albuminCellsAnimalsRat embryo fibroblastsSpecific damageSerum albuminFibroblastsConjugatesCYTOTOXICITY MEDIATED BY SOLUBLE ANTIGEN AND LYMPHOCYTES IN DELAYED HYPERSENSITIVITY
Ruddle N, Waksman B. CYTOTOXICITY MEDIATED BY SOLUBLE ANTIGEN AND LYMPHOCYTES IN DELAYED HYPERSENSITIVITY. Journal Of Experimental Medicine 1968, 128: 1267-1279. PMID: 5693925, PMCID: PMC2138574, DOI: 10.1084/jem.128.6.1267.Peer-Reviewed Original ResearchConceptsLymph node cellsNode cellsNormal lymph node cellsReaction of lymphocytesPresence of PPDDelayed hypersensitivitySoluble antigenSpecific antigenCytopathic effectAntigenPreincubation studiesTarget fibroblastsSensitized cellsMarked increaseAcid phosphatase contentLymphocytesSupernatant fluidCytotoxic activityPPDFibroblastsCellsPhosphatase contentHrRat embryo fibroblastsLymph
1967
Cytotoxic Effect of Lymphocyte-Antigen Interaction in Delayed Hypersensitivity
Ruddle N, Waksman B. Cytotoxic Effect of Lymphocyte-Antigen Interaction in Delayed Hypersensitivity. Science 1967, 157: 1060-1062. PMID: 6036235, DOI: 10.1126/science.157.3792.1060.Peer-Reviewed Original Research