2020
Intestinal TMEM16A function as a luminal chloride channel
Kazi M, Saha T, Aoun J, Hayashi M, Sheikh I, Leblanc N, Sarkar P, Ameen N, Woodward O. Intestinal TMEM16A function as a luminal chloride channel. The FASEB Journal 2020, 34: 1-1. DOI: 10.1096/fasebj.2020.34.s1.06115.Peer-Reviewed Original ResearchMouse intestinal tissueIntestinal tissueHuman colonic tissueColonic tissueLuminal expressionLuminal ClTMEM16A protein expressionIntestinal epithelial tissueAvailable polyclonal antibodyLuminal membraneWestern blot analysisTMEM16A functionSerosal applicationAgonist carbacholDistal colonCarbacholMRNA expressionColonWestern blotMouse intestineT84 cellsHigh expressionHuman colonProtein expressionTMEM16A protein
2018
Establishment of Microvillus Inclusion Disease (MVID) human models using small intestinal enteroids and embryonic stem cells
Figueroa‐Hall L, Ameen N. Establishment of Microvillus Inclusion Disease (MVID) human models using small intestinal enteroids and embryonic stem cells. The FASEB Journal 2018, 32: 750.31-750.31. DOI: 10.1096/fasebj.2018.32.1_supplement.750.31.Peer-Reviewed Original ResearchMicrovillus inclusion diseaseHuman intestinal modelSmall intestineIntestinal modelSeverity of illnessIntestinal organoidsSmall intestinal modelProximal small intestineCancer-derived cell linesFull-text articlesDevelopment of therapiesStem cellsIntestinal cell modelSmall intestinal organoidsIntestinal enteroidsInclusion diseasePathognomonic featuresSecretory diarrheaEpithelial diseaseHuman embryonic stem cellsIntestinal tissueIntestine resultsTransporter traffickingAppropriate research modelsLentiviral transfection