Featured Publications
Enhancing outcomes in IVF laboratories: navigating the human element through leadership and emotional intelligence
Basar M. Enhancing outcomes in IVF laboratories: navigating the human element through leadership and emotional intelligence. Journal Of Assisted Reproduction And Genetics 2024, 41: 2557-2567. PMID: 39225839, PMCID: PMC11535114, DOI: 10.1007/s10815-024-03239-x.Peer-Reviewed Original ResearchLeadership styleHuman factorsTeam dynamicsEmotional intelligenceHuman elementManagement developmentStaff well-beingToxic workplacesLeadershipEI trainingPromote emotional intelligenceSoft skillsOperational frameworkWell-beingReview contemporary literatureAcademic communityTeamTechnical expertisePersonality dynamicsContemporary literatureInterpersonal aspectsStyleWorkplaceStaff membersEmbryology with precision: effective quality control in the in vitro fertilization laboratory
Basar M, Unsal E, Ergun Y. Embryology with precision: effective quality control in the in vitro fertilization laboratory. Current Opinion In Obstetrics & Gynecology 2024, 36: 200-207. PMID: 38572581, DOI: 10.1097/gco.0000000000000945.Peer-Reviewed Original ResearchConceptsPreimplantation genetic testingIn vitro fertilizationIntracytoplasmic sperm injectionProportion of mature oocytesIn vitro fertilization treatmentClinical pregnancy rateClinical practiceIn vitro fertilization laboratoryEmbryo development ratesImprove IVF outcomesSuccess rateImproving clinical outcomesField of reproductive medicineSperm injectionIVF outcomesClinical outcomesIVF treatmentDiagnostic accuracySuccess rate of IVF treatmentIVF proceduresPregnancy rateGenetic testingMature oocytesReproductive medicineGenetics laboratories
2024
Artificial Intelligence in IVF Laboratories: Elevating Outcomes Through Precision and Efficiency
Hew Y, Kutuk D, Duzcu T, Ergun Y, Basar M. Artificial Intelligence in IVF Laboratories: Elevating Outcomes Through Precision and Efficiency. Biology 2024, 13: 988. DOI: 10.3390/biology13120988.Peer-Reviewed Original ResearchArtificial intelligenceIn vitro fertilizationPattern recognition capabilitiesHuman-machine interfaceData securityReducing human errorIn vitro fertilization laboratoryDeep learningNeural networkMachine learningAI technologyAlgorithmic biasRecognition capabilityReproductive medicineHuman errorSperm selectionEffects of AIStandard processIntelligenceIncreased accuracySensitivity fieldPersonalized treatment plansQuality assuranceOperational efficiencyLearningComparison of the Mitophagy and Apoptosis Related Gene Expressions in Waste Embryo Culture Medium of Female Infertility Types
Kütük D, Öner Ç, Başar M, Akcay B, Olcay İ, Çolak E, Selam B, Cincik M. Comparison of the Mitophagy and Apoptosis Related Gene Expressions in Waste Embryo Culture Medium of Female Infertility Types. Life 2024, 14: 1507. PMID: 39598305, PMCID: PMC11595419, DOI: 10.3390/life14111507.Peer-Reviewed Original ResearchPolycystic ovary syndromePoor ovarian reservePINK1 gene expressionGene expressionOocyte-to-embryo transitionEmbryo culture fluidApoptosis related gene expressionNormorespondersIVF centerInfertility typeCellular parametersMitochondrial DNAP53 gene expressionOvarian reserveFemale infertilityRelated gene expressionPINK1HumaninMitochondrial dysfunctionReal time PCRMfn2Embryonic development periodInfertile patientsMfn1Culture fluidBeyond Earth’s bounds: navigating the frontiers of Assisted Reproductive Technologies (ART) in space
Chaplia O, Mathyk B, Nichols-Burns S, Basar M, Halicigil C. Beyond Earth’s bounds: navigating the frontiers of Assisted Reproductive Technologies (ART) in space. Reproductive Biology And Endocrinology 2024, 22: 123. PMID: 39394617, PMCID: PMC11468284, DOI: 10.1186/s12958-024-01290-y.Peer-Reviewed Original ResearchConceptsAssisted reproductive technologyIn vitro embryo developmentReproductive technologyRadiation-induced damageGamete handlingClinical embryologistsReproductive endocrinologistsTemperature limitEmbryo cultureReproductive medicineLow Earth orbitEmbryo developmentDeep space travelEarth orbitSpace environmentInterplanetary speciesEarth-boundMicrofluidic devicesCryopreservationSERUM ANTI-MULLERIAN HORMONE IS ASSOCIATED WITH PREOVULATORY FOLLICLE CUMULUS CELL MITOCHONDRIAL DNA COPY NUMBER
Volovsky M, Seifer D, Sahin G, Chaplia O, Nichols-Burns S, Basar M, Seli E, Halicigil C. SERUM ANTI-MULLERIAN HORMONE IS ASSOCIATED WITH PREOVULATORY FOLLICLE CUMULUS CELL MITOCHONDRIAL DNA COPY NUMBER. Fertility And Sterility 2024, 122: e199. DOI: 10.1016/j.fertnstert.2024.07.662.Peer-Reviewed Original ResearchEXAMINING RELEVANCE OF AGE AND BODY MASS INDEX FOR EMBRYO MORPHOKINETICS
Dzienny A, Wesevich V, Nichols-Burns S, Chaplia O, Basar M, Unsal E, Halicigil C, Pal L. EXAMINING RELEVANCE OF AGE AND BODY MASS INDEX FOR EMBRYO MORPHOKINETICS. Fertility And Sterility 2024, 122: e195. DOI: 10.1016/j.fertnstert.2024.07.652.Peer-Reviewed Original ResearchEVALUATING THE EFFECTIVENESS OF CONVENTIONAL IVF IN CASES WITH LOW OOCYTE YIELD AND ADVANCED MATERNAL AGE (AMA)
Nichols-Burns S, Chaplia O, Unsal E, Basar M, Halicigil C. EVALUATING THE EFFECTIVENESS OF CONVENTIONAL IVF IN CASES WITH LOW OOCYTE YIELD AND ADVANCED MATERNAL AGE (AMA). Fertility And Sterility 2024, 122: e287-e288. DOI: 10.1016/j.fertnstert.2024.07.891.Peer-Reviewed Original ResearchTHE IMPACT OF ENDOMETRIAL AND EMBRYO RELATED FACTORS ON CLINICAL OUTCOMES AND LIVE BIRTH IN PROGRAMMED AND MODIFIED NATURAL FET CYCLES WITH EUPLOID EMBRYO TRANSFERS
Halicigil C, Basar M, Chaplia O, Nichols-Burns S. THE IMPACT OF ENDOMETRIAL AND EMBRYO RELATED FACTORS ON CLINICAL OUTCOMES AND LIVE BIRTH IN PROGRAMMED AND MODIFIED NATURAL FET CYCLES WITH EUPLOID EMBRYO TRANSFERS. Fertility And Sterility 2024, 122: e65. DOI: 10.1016/j.fertnstert.2024.07.249.Peer-Reviewed Original ResearchUnderstanding how space travel affects the female reproductive system to the Moon and beyond
Mathyk B, Imudia A, Quaas A, Halicigil C, Karouia F, Avci P, Nelson N, Guzeloglu-Kayisli O, Denbo M, Sanders L, Scott R, Basar M, Guevara-Cerdán A, Strug M, Monseur B, Kayisli U, Szewczyk N, Mason C, Young S, Tasoglu S, Costes S, Beheshti A. Understanding how space travel affects the female reproductive system to the Moon and beyond. Npj Women's Health 2024, 2: 20. DOI: 10.1038/s44294-024-00009-z.Peer-Reviewed Original ResearchHypothalamic-pituitary-gonadalFemale reproductive systemEndometrial receptivityReproductive endocrinologyHealthy live birthPreimplantation embryo developmentHypothalamic-pituitary-gonadal (HPG) axisFemale reproductive healthReproductive systemOvarian folliculogenesisCircadian rhythm changesLive birthsEmbryo implantationFemale reproductive endocrinologyEffects of space travelPregnancySpace travelReproductive healthEmbryo developmentRhythm changesAdverse effectsEndocrinologySuccessful transitionEffects of spaceflightInterplanetary speciesMitochondrial Unfolded Protein Response Gene Clpp Is Required for Oocyte Function and Female Fertility
Ergun Y, Imamoglu A, Cozzolino M, Demirkiran C, Basar M, Garg A, Yildirim R, Seli E. Mitochondrial Unfolded Protein Response Gene Clpp Is Required for Oocyte Function and Female Fertility. International Journal Of Molecular Sciences 2024, 25: 1866. PMID: 38339144, PMCID: PMC10855406, DOI: 10.3390/ijms25031866.Peer-Reviewed Original ResearchConceptsCaseinolytic peptidase PMouse modelProtein homeostasisStress responseUnfolded protein stress responseProtein stress responseCumulus/granulosa cellsOocyte competenceOocyte functionGlobal deletionFunctional abnormalitiesGenes clpPMetabolic stress responseFemale subfertilityFemale infertilityOocyte-specificOocytesReproductive functionMtUPRMiceProtein degradationReproductive competenceFemale fertilityDeletionHomeostasisMitochondrial Unfolded Protein Response Gene Clpp Is Required for Oocyte Function and Female Fertility
PubmedPeer-Reviewed Original Research
2023
"The Role of Implantation Rate and Embryo Culture Conditions in IVF Success: An Opinion"
Basar M. "The Role of Implantation Rate and Embryo Culture Conditions in IVF Success: An Opinion". Biomedical Journal Of Scientific & Technical Research 2023, 53 DOI: 10.26717/bjstr.2023.53.008374.Peer-Reviewed Original ResearchHistorical Roadmap of Preimplantation Genetic Testing from Past to Present; What is Expected in the Future?
Basar M. Historical Roadmap of Preimplantation Genetic Testing from Past to Present; What is Expected in the Future? Reproductive Medicine Gynaecology & Obstetrics 2023, 8: 1-8. DOI: 10.24966/rmgo-2574/100129.Peer-Reviewed Original ResearchHistorical Roadmap of Preimplantation Genetic Testing from Past to Present; What is Expected in the Future?
@article{Basar_2023, doi = {10.24966/rmgo-2574/100129}, url = {https://doi.org/10.24966%2Frmgo-2574%2F100129}, year = 2023, month = {mar}, publisher = {Herald Scholarly Open Access}, volume = {8}, number = {1}, pages = {1--8}, author = {Murat Basar and}, title = {Historical Roadmap of Preimplantation Genetic Testing from Past to Present$\mathsemicolon$ What is Expected in the Future?}, journal = {Journal of Reproductive Medicine, Gynaecology {\&}amp$\mathsemicolon$ Obstetrics}}Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsThe Unseen Crisis: Embryologist Burnout and its Impact on IVF Success Rates
ISI IndexedCommentaries, Editorials and LettersThe Role of Implantation Rate and Embryo Culture Conditions in IVF Success: An Opinion
ISI IndexedPeer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsFlow Cytometry-Based Assay to Identify A Competent Embryo in FET Cycles
Akcay B, Meric N, Olcay I, Ergun Y, Boynukalin K, Arici A, Bahceci M, Basar M. Flow Cytometry-Based Assay to Identify A Competent Embryo in FET Cycles. Archives Of Clinical And Biomedical Research 2023, 07 DOI: 10.26502/acbr.50170357.Peer-Reviewed Original Research
2022
Mitochondrial Dysfunction, Mitophagy and Their Correlation with Perinatal Complications: Preeclampsia and Low Birth Weight
Yildirim R, Ergun Y, Basar M. Mitochondrial Dysfunction, Mitophagy and Their Correlation with Perinatal Complications: Preeclampsia and Low Birth Weight. Biomedicines 2022, 10: 2539. PMID: 36289801, PMCID: PMC9599185, DOI: 10.3390/biomedicines10102539.Peer-Reviewed Original ResearchLow birth weightBirth weightProgression of preeclampsiaFetal growthPerinatal complicationsFetal mortalityPlacental implantationPrenatal complicationsMitochondrial dysfunctionPreeclampsiaPathophysiologyReactive oxygen speciesReceptor-mediated mitophagyComplicationsMitochondrial quality control mechanismsAccumulation of damaged mitochondriaDysfunctionAccumulation of reactive oxygen speciesDouble-membrane vesiclesCellular survivalQuality control mechanismsAutophagy of mitochondriaPathologyOxygen speciesMitochondrial networkICSI IS ASSOCIATED WITH LOWER BLASTULATION RATES COMPARED TO CONVENTIONAL IVF AMONG COUPLES WITH NON-MALE FACTOR INFERTILITY AND LOW OOCYTE YIELD
Beroukhim G, Seifer D, Chaplia O, Nichols-Burns S, Basar M, Halicigil C. ICSI IS ASSOCIATED WITH LOWER BLASTULATION RATES COMPARED TO CONVENTIONAL IVF AMONG COUPLES WITH NON-MALE FACTOR INFERTILITY AND LOW OOCYTE YIELD. Fertility And Sterility 2022, 118: e143. DOI: 10.1016/j.fertnstert.2022.08.419.Peer-Reviewed Original Research