2020
Implementation of the TaperGuard™ endotracheal tube in an unselected surgical population to reduce postoperative pneumonia
Martini RP, Yanez ND, Treggiari MM, Tekkali P, Soelberg C, Aziz MF. Implementation of the TaperGuard™ endotracheal tube in an unselected surgical population to reduce postoperative pneumonia. BMC Anesthesiology 2020, 20: 211. PMID: 32838740, PMCID: PMC7446207, DOI: 10.1186/s12871-020-01117-4.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCohort StudiesEquipment DesignFemaleHumansInterrupted Time Series AnalysisIntubation, IntratrachealMaleMiddle AgedPneumonia, Ventilator-AssociatedPostoperative ComplicationsRisk FactorsConceptsPostoperative pneumoniaSubgroup of patientsBaseline cohortSurgical patientsIntervention cohortEndotracheal intubationOdds ratioNational Surgical Quality Improvement ProjectSurgical Quality Improvement ProjectUnselected surgical populationUnadjusted odds ratioHigh-risk populationPatient-level dataRisk of ventilatorQuality improvement projectInterrupted time series designElectronic health recordsHospital mortalityVAP bundleSurgical populationPatient characteristicsPneumonia riskHistoric cohortHospital admissionFurther risk reduction
2016
Randomized Pilot Trial of Two Modified Endotracheal Tubes To Prevent Ventilator-associated Pneumonia
Deem S, Yanez D, Sissons-Ross L, Broeckel JA, Daniel S, Treggiari M. Randomized Pilot Trial of Two Modified Endotracheal Tubes To Prevent Ventilator-associated Pneumonia. Annals Of The American Thoracic Society 2016, 13: 72-80. PMID: 26523433, PMCID: PMC4722846, DOI: 10.1513/annalsats.201506-346oc.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedEquipment DesignEquipment SafetyFemaleHumansIntubation, IntratrachealMaleMiddle AgedPilot ProjectsPneumonia, Ventilator-AssociatedTreatment OutcomeConceptsEndotracheal tubeTracheal colonizationChest radiograph criteriaOccurrence of VAPPrevention of VAPCoprimary end pointsSerious adverse eventsInstitutional review board approvalEmergency endotracheal intubationStandard endotracheal tubeMajority of intubationsReview board approvalModified Endotracheal TubeSafety concernsAdverse eventsVAP preventionEndotracheal intubationSubglottic secretionsEmergency intubationClinical trialsClinical signsNosocomial infectionsPilot trialStudy groupHospital setting
2010
New endotracheal tubes designed to prevent ventilator-associated pneumonia: do they make a difference?
Deem S, Treggiari MM. New endotracheal tubes designed to prevent ventilator-associated pneumonia: do they make a difference? Respiratory Care 2010, 55: 1046-55. PMID: 20667152.Peer-Reviewed Original ResearchMeSH KeywordsBiofilmsHumansIntention to Treat AnalysisIntubation, IntratrachealPatient SelectionPneumonia, Ventilator-AssociatedSuctionConceptsEndotracheal tubeVAP preventionVentilator-associated pneumoniaNew endotracheal tubeImportant patient outcomesInfection control methodsModified Endotracheal TubeCost-effectiveness dataProper patient positioningOral hygienePatient outcomesNosocomial infectionsInsufficient evidencePatient careStrong recommendationsImportant safety concernsPatient positioningMeticulous attentionPneumoniaSuch interventionsMicroaspirationSafety concernsMultifaceted approachPreventionFuture studies