2014
Assessment of Circulating Blood Volume with Fluid Administration Targeting Euvolemia or Hypervolemia
Joffe AM, Khandelwal N, Hallman MR, Treggiari MM. Assessment of Circulating Blood Volume with Fluid Administration Targeting Euvolemia or Hypervolemia. Neurocritical Care 2014, 22: 82-88. PMID: 25142828, DOI: 10.1007/s12028-014-9993-8.Peer-Reviewed Original ResearchConceptsSubgroup of patientsBlood volumeHV groupDay 5Fluid administrationFluid balanceDelayed ischemic neurologic deficitsCrystalloid fluid administrationIschemic neurologic deficitCumulative fluid balanceML/Higher fluid balanceT-testStudent's t-testProphylactic hypervolemiaICU admissionICU stayResultsTwenty patientsNeurologic deficitsCerebral vasospasmClinical trialsHypervolemiaNormovolemiaBVA-100Concurrent group
2013
Validity of Exchangeable Solute Balance as a Measure of Blood Volume in Neurologically Injured Adults
Joffe AM, Healey L, Khandelwal N, Hallman MR, Van Cleve W, Treggiari MM. Validity of Exchangeable Solute Balance as a Measure of Blood Volume in Neurologically Injured Adults. Neurocritical Care 2013, 21: 102-107. PMID: 24057812, DOI: 10.1007/s12028-013-9915-1.Peer-Reviewed Original ResearchConceptsBlood volumeFluid balanceNeuroscience intensive care unitBV measurementsExtracellular fluidConsecutive adult patientsLarge academic medical centerIntensive care unitAcademic medical centerBV testResults55 patientsAdult patientsRoutine careCare unitTotal body waterCapillary leakActual blood volumeMedical CenterRobust variance estimationBVA-100MethodsThe UniversityAlbumin injectionNumber of daysPatientsBody water
2011
The association between fluid balance and outcomes after subarachnoid hemorrhage
Martini RP, Deem S, Brown M, Souter MJ, Yanez ND, Daniel S, Treggiari MM. The association between fluid balance and outcomes after subarachnoid hemorrhage. Neurocritical Care 2011, 17: 191-198. PMID: 21688008, DOI: 10.1007/s12028-011-9573-0.Peer-Reviewed Original ResearchConceptsPositive fluid balanceICU day 3Negative fluid balanceFluid balanceNew strokeSubarachnoid hemorrhageDay 3Early fluid balanceLevel 1 traumaCumulative fluid balanceWorse clinical presentationMultivariable logistic regressionLess urine outputHunt-Hess scoreGreater resource useTCD vasospasmHospital deathHospital mortalityICU admissionTroponin elevationAdmission GCSHospital courseHospital lengthAdult patientsPrimary outcome