2024
β1-adrenoceptor expression on GABAergic interneurons in primate dorsolateral prefrontal cortex: potential role in stress-induced cognitive dysfunction
Joyce M, Yang S, Morin K, Duque A, Arellano J, Datta D, Wang M, Arnsten A. β1-adrenoceptor expression on GABAergic interneurons in primate dorsolateral prefrontal cortex: potential role in stress-induced cognitive dysfunction. Neurobiology Of Stress 2024, 30: 100628. PMID: 38550854, PMCID: PMC10973161, DOI: 10.1016/j.ynstr.2024.100628.Peer-Reviewed Original ResearchDorsolateral prefrontal cortexPrefrontal cortexStress-induced cognitive dysfunctionTreat stress-related disordersPrimate dorsolateral prefrontal cortexImpaired working memoryWorking memory deficitsWorking memory taskCalcium-binding proteins calbindinStress-related disordersClasses of inhibitory neuronsLevels of norepinephrineFast-spikingMemory taskDopamine releaseWorking memoryMemory deficitsInhibitory neuronsCognitive dysfunctionPV interneuronsGABAergic interneuronsDlPFCBehavior analysisCortexPyramidal cells
2017
mGluR2/3 mechanisms in primate dorsolateral prefrontal cortex: evidence for both presynaptic and postsynaptic actions
Jin L, Wang M, Yang S, Yang Y, Galvin V, Lightbourne T, Ottenheimer D, Zhong Q, Stein J, Raja A, Paspalas C, Arnsten A. mGluR2/3 mechanisms in primate dorsolateral prefrontal cortex: evidence for both presynaptic and postsynaptic actions. Molecular Psychiatry 2017, 22: 1511-1511. DOI: 10.1038/mp.2017.206.Peer-Reviewed Original Research
2009
5.3 Dopamine’s Influence on Prefrontal Cortical Cognition: Actions and Circuits in Behaving Primates
Arnsten A, Vijayraghavan S, Wang M, Gamo N, Paspalas C. 5.3 Dopamine’s Influence on Prefrontal Cortical Cognition: Actions and Circuits in Behaving Primates. 2009, 230-248. DOI: 10.1093/acprof:oso/9780195373035.003.0016.Peer-Reviewed Original Research
2004
Protein Kinase C Overactivity Impairs Prefrontal Cortical Regulation of Working Memory
Birnbaum SG, Yuan PX, Wang M, Vijayraghavan S, Bloom AK, Davis DJ, Gobeske KT, Sweatt JD, Manji HK, Arnsten AF. Protein Kinase C Overactivity Impairs Prefrontal Cortical Regulation of Working Memory. Science 2004, 306: 882-884. PMID: 15514161, DOI: 10.1126/science.1100021.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic alpha-AgonistsAlkaloidsAnimalsBenzophenanthridinesCarbolinesElectrophysiologyEnzyme ActivationFemaleImidazolesLithium CarbonateMacaca mulattaMaleMemoryNeuronsPhenanthridinesPrefrontal CortexProtein Kinase CRatsRats, Sprague-DawleyReceptors, Adrenergic, alpha-1Signal TransductionStress, PhysiologicalTetradecanoylphorbol AcetateValproic AcidConceptsPrefrontal cortical regulationPrefrontal cortexPrefrontal cortical cognitive functionCortical regulationCortical cognitive functionsPrefrontal cortical dysfunctionWorking memoryElectrophysiological measuresCognitive functionRepresentational knowledgeThought disorderImpaired judgmentBrain regionsStress exposureMemoryCortical dysfunctionHigher brain regionsCortexThoughtDistractibilityEmotionsImpulsivityHigh levelsJudgmentsBehavior