2010
Th2 LCR is essential for regulation of Th2 cytokine genes and for pathogenesis of allergic asthma
Koh BH, Hwang SS, Kim JY, Lee W, Kang MJ, Lee CG, Park JW, Flavell RA, Lee GR. Th2 LCR is essential for regulation of Th2 cytokine genes and for pathogenesis of allergic asthma. Proceedings Of The National Academy Of Sciences Of The United States Of America 2010, 107: 10614-10619. PMID: 20483988, PMCID: PMC2890814, DOI: 10.1073/pnas.1005383107.Peer-Reviewed Original ResearchConceptsCD4 T cellsAllergic asthmaTh2 cytokine genesCytokine genesKO miceT cellsNaïve CD4 T cellsLung airway inflammationSerum IgE levelsBronchoalveolar lavage fluidRecruitment of eosinophilsWild-type miceAirway hyperresponsivenessOvalbumin challengeAirway inflammationIgE levelsLavage fluidTh2 cytokinesAirway wallMucus productionMouse modelAsthmaMarked reductionCre-loxP recombinationMice
2002
A Case of Giant Cell Interstitial Pneumonia without History of Exposure to Hard Metal
Hong J, Lee J, Kang M, Kim D, Jung K, Jang K, Park H, Lee I. A Case of Giant Cell Interstitial Pneumonia without History of Exposure to Hard Metal. Tuberculosis And Respiratory Diseases 2002, 52: 419-424. DOI: 10.4046/trd.2002.52.4.419.Peer-Reviewed Original ResearchGiant cellsGiant cell interstitial pneumoniaEmphysematous lung changesOpen lung biopsyLower lung fieldGround-glass opacitiesYear old manBronchial lavage fluidHard metal exposureHistory of exposureOral corticosteroidsExertional dyspneaLung biopsyLung changesInterstitial pneumoniaGlass opacitiesInterstitial fibrosisLavage fluidRadiographic abnormalitiesSpirometric valuesChest radiographyMacrophage compartmentLung fieldsCT scanOccupational history