2016
Cutaneous T-cell lymphoma (CTCL): Current practices in blood assessment and the utility of T-cell receptor (TCR)-Vβ chain restriction
Gibson JF, Huang J, Liu KJ, Carlson KR, Foss F, Choi J, Edelson R, Hussong JW, Mohl R, Hill S, Girardi M. Cutaneous T-cell lymphoma (CTCL): Current practices in blood assessment and the utility of T-cell receptor (TCR)-Vβ chain restriction. Journal Of The American Academy Of Dermatology 2016, 74: 870-877. PMID: 26874819, PMCID: PMC4835257, DOI: 10.1016/j.jaad.2015.12.018.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCross-Sectional StudiesFemaleFlow CytometryHematologic TestsHumansInternationalityLymphoma, T-Cell, CutaneousMaleMiddle AgedMycosis FungoidesNeoplasm InvasivenessNeoplasm StagingPolymerase Chain ReactionPractice Guidelines as TopicPredictive Value of TestsPrognosisRare DiseasesReceptors, Antigen, T-CellRetrospective StudiesSezary SyndromeSkin NeoplasmsSocieties, MedicalConceptsCutaneous T-cell lymphomaT-cell lymphomaCurrent clinical practiceClinical practicePredictive valueNegative predictive valuePositive predictive valueCurrent International SocietyT cell receptorImmunophenotypic abnormalitiesEvidence of clonalitySingle centerTumor burdenBlood assessmentClinical benefitPeripheral bloodCohort casesDisease burdenPolymerase chain reactionStaging criteriaChain restrictionRetrospective analysisMalignant cellsFlow cytometryDiagnostic algorithm
2015
The difficult—and often delayed—diagnosis of CTCL
Weed J, Girardi M. The difficult—and often delayed—diagnosis of CTCL. Science Translational Medicine 2015, 7: 308fs41. PMID: 26446952, DOI: 10.1126/scitranslmed.aad2518.Peer-Reviewed Original Research
2006
Selection of the cutaneous intraepithelial γδ+ T cell repertoire by a thymic stromal determinant
Lewis JM, Girardi M, Roberts SJ, D Barbee S, Hayday AC, Tigelaar RE. Selection of the cutaneous intraepithelial γδ+ T cell repertoire by a thymic stromal determinant. Nature Immunology 2006, 7: 843-850. PMID: 16829962, DOI: 10.1038/ni1363.Peer-Reviewed Original ResearchConceptsT cellsIntraepithelial lymphocytesT cell receptorMouse dendritic epidermal T-cellsOligoclonal T-cell receptorsDendritic epidermal T cellsEpidermal T cellsT cell repertoireT cell progenitorsCutaneous pathologyCell repertoireThymic stromaStromal determinantsLymphocyte repertoireCell receptorLymphocytesCell progenitorsHeritable defectsCellsIntraepithelialAgonistsMicePathologyPhysiological useStroma
1995
α β and γ δ T cells can share a late common precursor
Dudley E, Girardi M, Owen M, Hayday A. α β and γ δ T cells can share a late common precursor. Current Biology 1995, 5: 659-669. PMID: 7552177, DOI: 10.1016/s0960-9822(95)00131-x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBase SequenceCell DifferentiationDendritic CellsDNA NucleotidyltransferasesGene Rearrangement, T-LymphocyteHematopoiesisHematopoietic Stem CellsMiceMice, Inbred C57BLMolecular Sequence DataPolymerase Chain ReactionPolymorphism, Restriction Fragment LengthReceptors, Antigen, T-Cell, alpha-betaReceptors, Antigen, T-Cell, gamma-deltaStochastic ProcessesT-Lymphocyte SubsetsVDJ RecombinasesConceptsDelta geneSuccessful rearrangementLineage-determining factorsT cell receptorGene rearrangement processTCR-alpha gene rearrangementsAlpha gene rearrangementsTCR beta locusVertebrate developmentTCR delta geneAlpha betaSeparate lineagesTCR delta locusProductive rearrangementsDelta gene segmentsDelta locusBeta locusPolypeptide chainIndividual thymocytesGenesGamma geneT cell differentiationGene segmentsFragment length polymorphism techniqueCommon precursor