Michael B. Bracken, PhD, MPH, FACE
Susan Dwight Bliss Professor EmeritusCards
Appointments
Contact Info
Chronic Disease Epidemiology
PO Box 208034, 60 College Street
New Haven, CT 06520-8034
United States
About
Titles
Susan Dwight Bliss Professor Emeritus
Biography
Dr. Michael Bracken is the Susan Dwight Bliss Professor Emeritus of Epidemiology, Senior Research Scientist in Epidemiology, and formerly Professor of Obstetrics and Gynecology, Reproductive Science and Neurology, a former Head of Chronic Disease Epidemiology at Yale University and former Vice Chairman (Deputy Dean) of the Yale School of Public Health where he has studied and taught for the last 52 years. He is a sometime Research Fellow in Green Templeton College, Oxford University. Professor Bracken has published some 400 articles in the scientific literature and has authored three books: Perinatal Epidemiology (1984) and Effective Care of the Newborn Infant (with J.C. Sinclair, 1992) both published by Oxford University Press. In 2006 this last book, which introduced the concepts of meta-analysis into neonatology, was named by the British Medical Journal as one of the most influential books in evidence-based medicine and was instrumental in assisting the foundation of the international Cochrane Collaboration. His new book: Risk, Chance and Causation: Investigating the Origins and Treatment of Disease was published by Yale University Press in 2013. He is the founding (in 1979) Director of the Yale Perinatal Epidemiology Unit and Director Emeritus of its successor, the Yale Center for Perinatal, Pediatric and Environmental Epidemiology. Professor Bracken has taught courses in evidence-based medicine and health care, pharmaco-epidemiology, perinatal epidemiology and general epidemiology at Yale for many years. He has directed numerous epidemiological investigations, almost all of which were funded (over $50 million in total) by the United States National Institutes of Health (NIH). He has served on numerous study sections and committees of the NIH including the Council of the National Institute of Deafness and Communicative Disorders. He chaired the first Congress of Epidemiology in 2001 and the first international colloquium on genome–wide association studies in 2006. He consults for many international corporations and agencies including the World Health Organization and he has served as the elected President of two major epidemiological organizations: the American College of Epidemiology and the Society for Epidemiologic Research. Professor Bracken is the 2013 recipient of the Lilienfeld Award from the American College of Epidemiology, a 2015 D.Sc honoris causa from the University of Gloucester in the UK, and the 2016 Gordon Lecture award from the National Institutes of Health.
Appointments
Chronic Disease Epidemiology
EmeritusPrimary
Other Departments & Organizations
Education & Training
- PhD
- Yale University (1974)
- MPhil
- Yale University (1972)
- MPH
- Yale University (1970)
- BSc (Hon)
- London University, Zoology (1968)
Research
Overview
The first randomized trials for evaluating therapies for acute spinal cord injury were designed and directed by Professor Bracken. He is a consultant for international corporations and government agencies and his government service includes NIH study sections and Council. He previously sat on the NIH Expert Panel on Genes Environment and Health.
- Identification of genetic polymorphisms that increase disease susceptibility and their interaction with lifestyle risk factors.
- Co-Founder and Co-Editor, Cochrane Neonatal Review Group, Cochrane Collaboration.
Medical Subject Headings (MeSH)
- View Lab Website
Yale Center for Perinatal, Pediatric and Environmental Epidemiology (CPPEE)
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Theodore Holford, PhD
Brian Leaderer, MPH, PhD
Elizabeth Triche
Joseph Piepmeier, MD, FAANS
Harlan Krumholz, MD, SM
Heping Zhang, PhD
Evidence-Based Medicine
Epidemiology
Perinatal Care
Publications
2022
Childhood asthma and household exposures to nitrogen dioxide and fine particles: a triple-crossover randomized intervention trial
Gent JF, Holford TR, Bracken MB, Plano JM, McKay LA, Sorrentino KM, Koutrakis P, Leaderer BP. Childhood asthma and household exposures to nitrogen dioxide and fine particles: a triple-crossover randomized intervention trial. Journal Of Asthma 2022, 60: 744-753. PMID: 35796019, PMCID: PMC10162040, DOI: 10.1080/02770903.2022.2093219.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsLevels of NOPersistent asthmaAsthma symptomsIntervention trialsNumber of asthmaDays of treatmentSymptom daysAsthma morbidityChildhood asthmaTreatment periodAsthmaCrossover designHousehold exposureSymptomsModest reductionTreatment effectsTreatmentGas stovesTrialsExposureTriple crossoverInterventionChildrenMixed modelsFurther research
2020
Pulmonary and cardiovascular safety of inhaled insulin in routine practice: The Exubera Large Simple Trial (VOLUME).
Gatto NM, Bracken MB, Kolitsopoulos F, Duggan WT, Koch GG, Wise RA, Jackson NC. Pulmonary and cardiovascular safety of inhaled insulin in routine practice: The Exubera Large Simple Trial (VOLUME). Contemporary Clinical Trials Communications 2020, 18: 100427. PMID: 32478195, PMCID: PMC7251384, DOI: 10.1016/j.conctc.2019.100427.Peer-Reviewed Original ResearchUpdating insights into rosiglitazone and cardiovascular risk through shared data: individual patient and summary level meta-analyses
Wallach JD, Wang K, Zhang AD, Cheng D, Grossetta Nardini HK, Lin H, Bracken MB, Desai M, Krumholz HM, Ross JS. Updating insights into rosiglitazone and cardiovascular risk through shared data: individual patient and summary level meta-analyses. The BMJ 2020, 368: l7078. PMID: 32024657, PMCID: PMC7190063, DOI: 10.1136/bmj.l7078.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsIndividual patient-level dataCardiovascular related deathsCardiovascular riskMyocardial infarctionRelated deathsSummary-level dataHeart failureOdds ratioSystematic reviewIncreased cardiovascular riskMore myocardial infarctionsHeart failure eventsCochrane Central RegistryAcute myocardial infarctionMyocardial infarction eventsPatient-level dataRandom-effects modelWeb of ScienceAnalysis of trialsEligible trialsComposite outcomeAdverse eventsContinuity correctionControlled TrialsRosiglitazone treatment
2019
Implications of product withdrawal on a post-approval pragmatic trial: The VOLUME study experience.
Kolitsopoulos FM, Gatto NM, Sweetland K, Bracken MB, Jackson N. Implications of product withdrawal on a post-approval pragmatic trial: The VOLUME study experience. Contemporary Clinical Trials Communications 2019, 16: 100477. PMID: 31799472, PMCID: PMC6883292, DOI: 10.1016/j.conctc.2019.100477.Peer-Reviewed Original ResearchAnalgesic use at ovulation and implantation and human fertility
Jukic AMZ, Padiyara P, Bracken MB, McConnaughey DR, Steiner AZ. Analgesic use at ovulation and implantation and human fertility. American Journal Of Obstetrics And Gynecology 2019, 222: 476.e1-476.e11. PMID: 31738897, PMCID: PMC7195999, DOI: 10.1016/j.ajog.2019.11.1251.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsNonaspirin nonsteroidal antiinflammatory drugsMedication useNonsteroidal antiinflammatory drugsAnalgesic useMenstrual cycleAntiinflammatory drugsPositive home pregnancy testPregnancy loss historyProspective cohort studyEntire menstrual cycleBody mass indexEffect of aspirinHistory of migraineYears of ageFrequency of intercourseHome pregnancy testsAspirin useFecundability ratiosCohort studyMass indexMedication usageImplantation windowUterine fibroidsClinical trialsPregnancy testSSRIs and autism: interpreting an umbrella review
Bracken MB. SSRIs and autism: interpreting an umbrella review. The Lancet Psychiatry 2019, 6: 893. PMID: 31631870, DOI: 10.1016/s2215-0366(19)30392-x.Commentaries, Editorials and LettersCitationsAltmetricLung Cancer-Related Mortality With Inhaled Insulin or a Comparator: Follow-Up Study of patients previously enrolled in Exubera Controlled Clinical Trials (FUSE) Final Results.
Gatto NM, Koralek DO, Bracken MB, Duggan WT, Lem J, Klioze S, Koch GG, Wise RA, Cohen RB, Jackson NC. Lung Cancer-Related Mortality With Inhaled Insulin or a Comparator: Follow-Up Study of patients previously enrolled in Exubera Controlled Clinical Trials (FUSE) Final Results. Diabetes Care 2019, 42: 1708-1715. PMID: 31331907, DOI: 10.2337/dc18-2529.Peer-Reviewed Original ResearchRandom-Effects Assumption in Meta-analyses
Bracken MB. Random-Effects Assumption in Meta-analyses. JAMA 2019, 322: 81-81. PMID: 31265092, DOI: 10.1001/jama.2019.5443.Commentaries, Editorials and LettersAltmetricMeSH Keywords
2018
Systematic review of efficacy and safety of retrievable inferior vena caval filters
Bikdeli B, Jiménez D, Kirtane AJ, Bracken MB, Spencer FA, Monreal M, Krumholz HM. Systematic review of efficacy and safety of retrievable inferior vena caval filters. Thrombosis Research 2018, 165: 79-82. PMID: 29579576, PMCID: PMC5943161, DOI: 10.1016/j.thromres.2018.03.014.Peer-Reviewed Original ResearchCitationsAltmetricMeSH KeywordsInferior Vena Cava Filters to Prevent Pulmonary Embolism: Systematic Review and Meta-Analysis
Bikdeli B, Chatterjee S, Desai N, Kirtane A, Desai M, Bracken M. Inferior Vena Cava Filters to Prevent Pulmonary Embolism: Systematic Review and Meta-Analysis. Journal Of Vascular Surgery Venous And Lymphatic Disorders 2018, 6: 135. DOI: 10.1016/j.jvsv.2017.10.008.Peer-Reviewed Original Research
Academic Achievements and Community Involvement
honor Gordon Lecture Award
International AwardNational Institutes of HealthDetails04/20/2016United Stateshonor Honorary Doctorate of Science
International AwardUniversity of GloucestershireDetails11/27/2015United Kingdomhonor Lilienfeld Award
International AwardAmerican College of EpidemiologyDetails09/24/2013United Statesactivity Asthma Causing Genes
ResearchDetails01/01/2008 - PresentUnited Kingdom; United KingdomAbstract/SynopsisProfessor Bracken collaborates with colleagues at Oxford University in a study of the genes that may increase susceptibility to asthma development and severity in children.
activity Caffeine Exposure during Pregnancy - Effects on Fetal Growth
ResearchDetails01/01/2008 - PresentNorway; NorwayAbstract/SynopsisDr. Bracken and Dr. Belanger are investigating the effects of caffeine exposure during pregancy on fetal growth.
Links & Media
News
- May 16, 2023
Nicole Deziel named co-director of the Yale Center for Perinatal, Pediatric, and Environmental Epidemiology
- May 02, 2022
Yale Center For Perinatal, Pediatric, and Environmental Epidemiology Hunts Through History to Answer Tomorrow's Research Questions
- May 02, 2022
Snapshots
- June 30, 2020
Senior YSPH Professors Retiring
Get In Touch
Contacts
Chronic Disease Epidemiology
PO Box 208034, 60 College Street
New Haven, CT 06520-8034
United States
Administrative Support
Locations
Yale Center for Perinatal Pediatric and Environmental Epidemiology (CPPEE)
Academic Office
1 Church Street, Ste 6th Floor
New Haven, CT 06510
Appointments
203.764.9375