2008
Maintenance treatment with buprenorphine and naltrexone for heroin dependence in Malaysia: a randomised, double-blind, placebo-controlled trial
Schottenfeld RS, Chawarski MC, Mazlan M. Maintenance treatment with buprenorphine and naltrexone for heroin dependence in Malaysia: a randomised, double-blind, placebo-controlled trial. The Lancet 2008, 371: 2192-2200. PMID: 18586174, PMCID: PMC4041792, DOI: 10.1016/s0140-6736(08)60954-x.Peer-Reviewed Original ResearchConceptsFirst heroin useHIV risk behaviorsHeroin dependenceHeroin useHeroin relapseMaintenance treatmentHeroin abstinenceDrug counsellingComputer-generated randomisation sequenceRisk behaviorsEffective public health approachConsecutive daysInterim safety analysisOutpatient research clinicPlacebo-controlled trialEfficacy of naltrexoneHeroin-dependent patientsMonths of enrollmentPrevention of relapseWorldwide health priorityPublic health approachRandomisation sequencePrimary outcomeHIV transmissionHIV risk
2000
Community reinforcement approach for combined opioid and cocaine dependence Patterns of engagement in alternate activities
Schottenfeld R, Pantalon M, Chawarski M, Pakes J, M.Ed. Community reinforcement approach for combined opioid and cocaine dependence Patterns of engagement in alternate activities. Journal Of Substance Use And Addiction Treatment 2000, 18: 255-261. PMID: 10742639, DOI: 10.1016/s0740-5472(99)00062-8.Peer-Reviewed Original ResearchConceptsCommunity Reinforcement ApproachNondrug-related activitiesDrug useGroup drug counselingClinical trialsDrug counselingReinforcement approachCocaine dependenceCurrent trialOpioidsAbstinenceSignificant differencesPatientsTrialsAlternate activitiesAverage hoursEffective overallTotal numberHoursRecreational activitiesActivityWeeksCocaine