1996
Acute cocaine effects on absolute cerebral blood flow
Wallace E, Wisniewski G, Zubal G, vanDyck C, Pfau S, Smith E, Rosen M, Sullivan M, Woods S, Kosten T. Acute cocaine effects on absolute cerebral blood flow. Psychopharmacology 1996, 128: 17-20. PMID: 8944401, DOI: 10.1007/s002130050104.Peer-Reviewed Original ResearchConceptsRelative cerebral blood flowCerebral blood flowBlood flowWhole-brain blood flowAbsolute cerebral blood flowBrain blood flowBlood flow changesAcute cocaine effectsRelative blood flow changesCocaine effectsMean decreaseCocaine useCocaine usersSignificant decreaseFlow changesMicrosphere modelVasoconstrictionStroke
1993
Effects of Acute Buprenorphine on Responses to Intranasal Cocaine: A Pilot Study
Rosen M, Pearsall H, McDougle C, Price L, Woods S, Kosten T. Effects of Acute Buprenorphine on Responses to Intranasal Cocaine: A Pilot Study. The American Journal Of Drug And Alcohol Abuse 1993, 19: 451-464. PMID: 8273766, DOI: 10.3109/00952999309001634.Peer-Reviewed Original Research
1992
Buprenorphine for cocaine and opiate dependence.
Kosten T, Rosen M, Schottenfeld R, Ziedonis D. Buprenorphine for cocaine and opiate dependence. Psychopharmacology Bulletin 1992, 28: 15-9. PMID: 1609037.Peer-Reviewed Original ResearchConceptsCocaine abuseMixed opioid agonist/antagonistOpioid agonist/antagonistPreliminary human studiesAgonists/antagonistsBuprenorphine treatmentOpioid dependenceMethadone maintenanceClinical trialsConcurrent dependencePreclinical studiesCocaine effectsBuprenorphineHuman studiesPlace preferenceChallenge studiesCocaineMethadoneTreatmentTrialsAbuseDose dependenceOpioidsAntagonistDaily