EIF1AX mutation in thyroid nodules: a histopathologic analysis of 56 cases in the context of institutional practices
Abi-Raad R, Xu B, Gilani S, Ghossein R, Prasad M. EIF1AX mutation in thyroid nodules: a histopathologic analysis of 56 cases in the context of institutional practices. Virchows Archiv 2024, 485: 859-867. PMID: 39225726, DOI: 10.1007/s00428-024-03914-5.Peer-Reviewed Original ResearchFollicular nodular diseaseAnaplastic thyroid carcinomaPapillary thyroid carcinomaEIF1AX mutationsBenign thyroid nodulesThyroid carcinomaThyroid nodulesOncocytic adenomasMolecular alterationsGenetic abnormalitiesNon-invasive follicular thyroid neoplasmPapillary-like nuclear featuresAssociated with malignant tumorsWHO 5th EditionCancer referral centerFollicular thyroid neoplasmTertiary care hospitalOncocytic carcinomaThyroid neoplasmsReferral centerNodular diseasePathological diagnosisCancer Genome AtlasMalignant tumorsEIF1AXMolecular Genetics Augment Cytopathologic Evaluation and Surgical Planning of Pediatric Thyroid Nodules
Spaulding S, Maayah M, Dinauer C, Prasad M, Darbinyan A, Morotti R, Christison-Lagay E. Molecular Genetics Augment Cytopathologic Evaluation and Surgical Planning of Pediatric Thyroid Nodules. Journal Of Pediatric Surgery 2024, 59: 975-980. PMID: 38246817, DOI: 10.1016/j.jpedsurg.2024.01.001.Peer-Reviewed Original ResearchFine-needle aspiration biopsyPediatric thyroid nodulesMolecular genetic testingBethesda IV nodulesPrediction of malignancyDICER1 mutationsThyroid nodulesGenetic testingNRAS mutationsMethods Retrospective chart reviewRetrospective chart reviewTime of surgeryBRAF V600E testingMutations/fusionsBethesda III nodulesChart reviewSurgical resectionFinal histopathologyThyroid resectionPediatric dataHistologic classificationSurgical specimensBRAF mutationsAspiration biopsyCytopathologic evaluation