2015
Clinical and Molecular Epidemiology of Methicillin-Resistant Staphylococcus aureus in a Neonatal Intensive Care Unit in the Decade following Implementation of an Active Detection and Isolation Program
Nelson MU, Bizzarro MJ, Baltimore RS, Dembry LM, Gallagher PG. Clinical and Molecular Epidemiology of Methicillin-Resistant Staphylococcus aureus in a Neonatal Intensive Care Unit in the Decade following Implementation of an Active Detection and Isolation Program. Journal Of Clinical Microbiology 2015, 53: 2492-2501. PMID: 26019206, PMCID: PMC4508396, DOI: 10.1128/jcm.00470-15.Peer-Reviewed Original ResearchMeSH KeywordsDNA, BacterialEpidemiological MonitoringFemaleGenetic VariationGenotypeGenotyping TechniquesHumansInfantInfant, NewbornIntensive Care Units, NeonatalMaleMethicillin-Resistant Staphylococcus aureusMolecular EpidemiologyMolecular TypingRetrospective StudiesStaphylococcal InfectionsVirulence FactorsConceptsNeonatal intensive care unitMethicillin-resistant Staphylococcus aureusIntensive care unitMRSA colonizationMolecular epidemiologyCare unitStaphylococcal cassette chromosome mec type IIAccessory gene regulator (agr) groupsMRSA colonization rateToxic shock syndrome toxinAgr group 1Exfoliative toxin AStaphylococcus aureusPotential virulence factor genesVirulence factor genesMRSA infectionSignificant morbidityClinical differencesPatient daysPulsed-field gel electrophoresisToxin AUSA300 strainGroup 1Continued vigilanceInfection
1998
Molecular Analysis of Glycopeptide-ResistantEnterococcus faecium Isolates Collected from Michigan Hospitals over a 6-Year Period
Thal L, Donabedian S, Robinson-Dunn B, Chow J, Dembry L, Clewell D, Alshab D, Zervos M. Molecular Analysis of Glycopeptide-ResistantEnterococcus faecium Isolates Collected from Michigan Hospitals over a 6-Year Period. Journal Of Clinical Microbiology 1998, 36: 3303-3308. PMID: 9774583, PMCID: PMC105319, DOI: 10.1128/jcm.36.11.3303-3308.1998.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Bacterial AgentsBacterial Typing TechniquesChromosomes, BacterialCross InfectionDNA, BacterialDrug Resistance, MicrobialElectrophoresis, Gel, Pulsed-FieldEnterococcus faeciumGene Transfer TechniquesGenes, BacterialGram-Positive Bacterial InfectionsHumansMichiganMolecular EpidemiologyNucleic Acid HybridizationPlasmidsVancomycinConceptsExtended-care facilityPulsed-field gel electrophoresisEnterococcus faecium isolatesFaecium isolatesClonal disseminationVancomycin-resistant E. faeciumStrain typesE. faecium isolatesVancomycin-resistant E. faecium isolatesIntrahospital disseminationSpread of resistanceMichigan hospitalsMajority of isolatesPatientsHospitalClinical isolatesGentamicin resistanceVanA geneErythromycin resistanceE. faeciumVancomycin resistanceType M2VanB genesMolecular relatednessMost isolatesNosocomial Candida glabrata Colonization: an Epidemiologic Study
Vazquez J, Dembry L, Sanchez V, Vazquez M, Sobel J, Dmuchowski C, Zervos M. Nosocomial Candida glabrata Colonization: an Epidemiologic Study. Journal Of Clinical Microbiology 1998, 36: 421-426. PMID: 9466752, PMCID: PMC104553, DOI: 10.1128/jcm.36.2.421-426.1998.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBone Marrow TransplantationCandidaCandidiasisChildChild, PreschoolCross InfectionDNA, FungalEnvironmental MicrobiologyFemaleHandHealth PersonnelHospitalizationHospitals, UniversityHumansIntensive Care UnitsMaleMiddle AgedMolecular EpidemiologyPolymorphism, Restriction Fragment LengthProspective StudiesRisk FactorsConceptsNosocomial acquisitionC. glabrataMedical intensive care unitBone marrow transplant unitPrior antimicrobial useDuration of hospitalizationIntensive care unitMarrow transplant unitSignificant risk factorsImportant nosocomial pathogenStrain typesSame strain typeCare unitTransplant unitUniversity HospitalRisk factorsEpidemiologic studiesPatientsC. glabrata strainsEnvironmental surfacesHospital personnelNosocomial pathogenAntimicrobial useIdentical strainsHospital environment
1994
DNA Analysis in the Study of the Epidemiology of Nosocomial Candidiasis
Dembry L, Vazquez J, Zervos M. DNA Analysis in the Study of the Epidemiology of Nosocomial Candidiasis. Infection Control And Hospital Epidemiology 1994, 15: 48-54. DOI: 10.2307/30148385.Peer-Reviewed Original ResearchConceptsCandida infectionsCandida speciesIntensive supportive careLonger patient survivalCurrent therapeutic regimensDisseminated Candida infectionFemale genital tractSevere Candida infectionsCandida albicans fungemiaImportant nosocomial pathogenNosocomial candidiasisAggressive treatmentPostoperative patientsSupportive careCrude mortalityIntensive carePatient survivalTherapeutic regimensCancer patientsBlood culturesGenital tractGastrointestinal tractViral infectionPatientsNosocomial pathogenDNA analysis in the study of the epidemiology of nosocomial candidiasis.
Dembry L, Vazquez J, Zervos M. DNA analysis in the study of the epidemiology of nosocomial candidiasis. Infection Control And Hospital Epidemiology 1994, 15: 48-53. PMID: 7907618, DOI: 10.1086/646817.Peer-Reviewed Original Research