2017
Continued midazolam versus diphenhydramine in difficult-to-sedate patients: a randomized double-blind trial
Sachar H, Pichetshote N, Nandigam K, Vaidya K, Laine L. Continued midazolam versus diphenhydramine in difficult-to-sedate patients: a randomized double-blind trial. Gastrointestinal Endoscopy 2017, 87: 1297-1303. PMID: 28159539, PMCID: PMC5537051, DOI: 10.1016/j.gie.2017.01.028.Peer-Reviewed Original ResearchConceptsDouble-blind trialAdequate sedationStudy medicationModerate sedationAlertness/Sedation scoreAdequacy of sedationStudy medication dosePsychiatric medication useModified Observer's AssessmentMOAA/SAdditional medicationElective colonoscopyPrimary endpointOpioid combinationsOpioid useMedication useMore patientsSedation scoreSuch patientsMedication doseUsual dosesBenzodiazepine useCurrent guidelinesSedate patientsSedation
2008
Esophageal capsule endoscopy for screening and surveillance of esophageal varices in patients with portal hypertension
de Franchis R, Eisen GM, Laine L, Fernandez‐Urien I, Herrerias JM, Brown RD, Fisher L, Vargas HE, Vargo J, Thompson J, Eliakim R. Esophageal capsule endoscopy for screening and surveillance of esophageal varices in patients with portal hypertension. Hepatology 2008, 47: 1595-1603. PMID: 18435461, DOI: 10.1002/hep.22227.Peer-Reviewed Original ResearchConceptsEsophageal varicesEsophageal capsule endoscopyNegative predictive valuePositive predictive valuePredictive valueCapsule endoscopyPortal hypertensionLarge esophageal varicesVariceal gradeLarge varicesMulticenter trialCurrent guidelinesEsophagogastroduodenoscopyTreatment decisionsVaricesCapsule studyPatientsEndoscopyPilot studyDiagnostic performanceEquivalence studyKappa scoresMinimal invasivenessCirrhosisHypertension