2022
International multicenter study comparing demographics, therapy and outcomes in bleeding from Mallory Weiss tears and peptic ulcers
Tham JE, Lynch L, Laursen SB, Laine L, Dalton HR, Ngu J, Redondo-Cerezo E, Schultz M, Murray I, Michell N, Morris AJ, Nielsen MM, Stanley AJ. International multicenter study comparing demographics, therapy and outcomes in bleeding from Mallory Weiss tears and peptic ulcers. Endoscopy International Open 2022, 10: e653-e658. PMID: 35571482, PMCID: PMC9106442, DOI: 10.1055/a-1784-0655.Peer-Reviewed Original ResearchMallory-Weiss tearUpper gastrointestinal bleedingPeptic ulcer bleedingEndoscopic therapyEndoscopic stigmataEpinephrine injectionAcute upper gastrointestinal bleedingInternational multicenter studyPUB patientsGastrointestinal bleedingUlcer bleedingUncommon causeMulticenter studyPeptic ulcerPoor outcomeScope clipInternational cohortClean baseLower riskBaseline parametersPatientsTherapyBleedingCommon modalityMortality
1996
A prospective outcome study of patients with clot in an ulcer and the effect of irrigation
Laine L, Stein C, Sharma V. A prospective outcome study of patients with clot in an ulcer and the effect of irrigation. Gastrointestinal Endoscopy 1996, 43: 107-110. PMID: 8635701, DOI: 10.1016/s0016-5107(06)80109-4.Peer-Reviewed Original ResearchConceptsUpper gastrointestinal bleedingEndoscopic therapyVisible vesselActive bleedingFurther bleedingGastrointestinal bleedingHemostatic therapyAdherent clotHigh-risk stigmataLow-risk findingsProspective outcome studyObservation of patientsInitial endoscopyEndoscopic findingsProspective studyExcellent outcomesUlcer baseBleedingClean baseOutcome studiesVigorous irrigationPatientsAppropriate managementVariable prevalenceTherapy
1992
Prospective evaluation of immediate versus delayed refeeding and prognostic value of endoscopy in patients with upper gastrointestinal hemorrhage
Laine L, Cohen H, Brodhead J, Cantor D, Garcia F, Mosquera M. Prospective evaluation of immediate versus delayed refeeding and prognostic value of endoscopy in patients with upper gastrointestinal hemorrhage. Gastroenterology 1992, 102: 314-316. PMID: 1727765, DOI: 10.1016/0016-5085(92)91816-m.Peer-Reviewed Original ResearchConceptsMallory-Weiss tearUpper gastrointestinal hemorrhageGastrointestinal hemorrhagePrognostic valueRegular dietMajor upper gastrointestinal hemorrhageClean-based ulcersEndoscopic evidenceHospital courseRecurrent bleedingEndoscopic findingsMajor hemorrhageClinical evidenceProspective evaluationVs. 5Entry criteriaClean baseVs. 2Lower riskPatientsUlcersUrgent interventionVs. 1HemorrhageTears