2022
The Society for Obstetric Anesthesia and Perinatology Coronavirus Disease 2019 Registry: An Analysis of Outcomes Among Pregnant Women Delivering During the Initial Severe Acute Respiratory Syndrome Coronavirus-2 Outbreak in the United States
Katz D, Bateman B, Kjaer K, Turner D, Spence N, Habib A, George R, Toledano R, Grant G, Madden H, Butwick A, Lynde G, Minehart R, Beilin Y, Houle T, Sharpe E, Kodali B, Bharadwaj S, Farber M, Palanisamy A, Prabhu M, Gonzales N, Landau R, Leffert L. The Society for Obstetric Anesthesia and Perinatology Coronavirus Disease 2019 Registry: An Analysis of Outcomes Among Pregnant Women Delivering During the Initial Severe Acute Respiratory Syndrome Coronavirus-2 Outbreak in the United States. Obstetric Anesthesia Digest 2022, 42: 27-28. DOI: 10.1097/01.aoa.0000816828.87126.61.Peer-Reviewed Original ResearchLow Molecular Weight Heparin, Unfractionated Heparin and Neuraxial Anaesthesia
Combs D, Leffert L. Low Molecular Weight Heparin, Unfractionated Heparin and Neuraxial Anaesthesia. 2022, 329-335. DOI: 10.1007/978-3-030-72487-0_49.Peer-Reviewed Original Research
2020
Risk Factors, Etiologies, and Screening Tools for Sepsis in Pregnant Women: A Multicenter Case-Control Study
Bauer M, Housey M, Bauer S, Behrmann S, Chau A, Clancy C, Clark E, Einav S, Langen E, Leffert L, Lin S, Madapu M, Maile M, McQuaid-Hanson E, Priessnitz K, Sela H, Shah A, Sobolewski P, Toledo P, Tsen L, Bateman B. Risk Factors, Etiologies, and Screening Tools for Sepsis in Pregnant Women: A Multicenter Case-Control Study. Obstetric Anesthesia Digest 2020, 40: 65-66. DOI: 10.1097/01.aoa.0000661332.57510.93.Peer-Reviewed Original ResearchMulticenter case-control studyCase-control studyMaternal sepsisQuick Sequential Organ Failure Assessment criteriaSequential Organ Failure Assessment criteriaSystemic inflammatory response syndrome criteriaPregnancy-related deathsSigns of sepsisMaternal morbidityMaternal outcomesSyndrome criteriaPrompt treatmentPregnant womenEarly sepsisRisk factorsSepsisEarly identificationDifferent screening methodsPregnancyScreening toolScreening criteriaPhysiological changesPrimary objectiveScreening methodHospitalization
2019
Acute Fatty Liver of Pregnancy: Pathophysiology, Anesthetic Implications, and Obstetrical Management
Naoum E, Leffert L, Chitilian H, Gray K, Bateman B. Acute Fatty Liver of Pregnancy: Pathophysiology, Anesthetic Implications, and Obstetrical Management. Obstetric Anesthesia Digest 2019, 39: 179-180. DOI: 10.1097/01.aoa.0000603636.83263.e8.Peer-Reviewed Original ResearchAcute Fatty Liver of Pregnancy: Pathophysiology, Anesthetic Implications, and Obstetrical Management.
Naoum EE, Leffert LR, Chitilian HV, Gray KJ, Bateman BT. Acute Fatty Liver of Pregnancy: Pathophysiology, Anesthetic Implications, and Obstetrical Management. Anesthesiology 2019, 130: 446-461. PMID: 30707120, PMCID: PMC7037575, DOI: 10.1097/aln.0000000000002597.Peer-Reviewed Original ResearchAnesthetic Management of Nonobstetric Surgery during Pregnancy
d’Arby Toledano R, Madden H, Leffert L. Anesthetic Management of Nonobstetric Surgery during Pregnancy. Current Anesthesiology Reports 2019, 9: 31-38. DOI: 10.1007/s40140-019-00314-3.Peer-Reviewed Original ResearchNonobstetric surgeryAnesthetic managementPhysiologic changesIntraoperative fetal monitoringAdequate pain managementMaternal cardiac arrestMaternal hypoxemiaNonurgent surgeryUteroplacental perfusionEmergent surgeryAspiration prophylaxisPain managementAnesthetic techniqueCardiac arrestLaparoscopic techniqueAnesthetic agentsRecent FindingsTherePregnancyFetal monitoringResuscitation algorithmSurgeryDiagnostic imagingOptimal timingReviewThis articleOptimal outcomes
2018
Canadian Stroke Best Practice Consensus Statement: Acute Stroke Management during pregnancy
Ladhani NNN, Swartz RH, Foley N, Nerenberg K, Smith EE, Gubitz G, Dowlatshahi D, Potts J, Ray JG, Barrett J, Bushnell C, Bal S, Chan WS, Chari R, Amrani M, Gandhi S, Hill MD, James A, Jeerakathil T, Jin A, Kirton A, Lanthier S, Lausman A, Leffert LR, Mandzia J, Menon B, Pikula A, Poppe A, Saposnik G, Sharma M, Bhogal S, Smitko E, Lindsay MP. Canadian Stroke Best Practice Consensus Statement: Acute Stroke Management during pregnancy. International Journal Of Stroke 2018, 13: 743-758. PMID: 30021491, DOI: 10.1177/1747493018786617.Peer-Reviewed Original ResearchConceptsAcute stroke managementStroke managementConsensus statementPost-stroke managementSecondary stroke preventionAcute stroke treatmentGroup of patientsInitial emergency managementBest available literatureStroke preventionAcute strokePostpartum managementAnesthetic managementHemorrhagic strokeStroke treatmentObstetric carePregnant womenMaternal healthPrior historyClinical considerationsConsensus documentPregnancyExpert consensusStrokeHealthcare professionals
2017
Canadian stroke best practice consensus statement: Secondary stroke prevention during pregnancy
Swartz RH, Ladhani NNN, Foley N, Nerenberg K, Bal S, Barrett J, Bushnell C, Chan WS, Chari R, Dowlatshahi D, Amrani ME, Gandhi S, Gubitz G, Hill MD, James A, Jeerakathil T, Jin A, Kirton A, Lanthier S, Lausman A, Leffert LR, Mandzia J, Menon B, Pikula A, Poppe A, Potts J, Ray J, Saposnik G, Sharma M, Smith EE, Bhogal S, Smitko E, Lindsay MP. Canadian stroke best practice consensus statement: Secondary stroke prevention during pregnancy. International Journal Of Stroke 2017, 13: 406-419. PMID: 29171360, DOI: 10.1177/1747493017743801.Peer-Reviewed Original ResearchMeSH KeywordsAnticoagulantsAntihypertensive AgentsCanadaCounselingDiabetes, GestationalDiabetic AngiopathiesFemaleHumansHydroxymethylglutaryl-CoA Reductase InhibitorsHypertensionIschemic Attack, TransientPlatelet Aggregation InhibitorsPostnatal CarePreconception CarePregnancyPregnancy Complications, CardiovascularPregnancy in DiabeticsPrenatal CareProfessional PracticeRisk FactorsSecondary PreventionStrokeConceptsSecondary stroke preventionStroke preventionConsensus statementUse of antithromboticsTransient ischemic attackBlood pressure managementIschemic stroke etiologyAspects of pregnancyHealth care professionalsGeneral management considerationsBest available literatureIschemic attackRecurrent strokeLipid managementStroke etiologyStroke riskFetal healthMaternal healthPrior historyFetal wellbeingCare professionalsClinical considerationsPregnancyConsensus documentExpert consensusThe incidence of pregnancy-related stroke: A systematic review and meta-analysis
Swartz RH, Cayley ML, Foley N, Ladhani NNN, Leffert L, Bushnell C, McClure J, Lindsay MP. The incidence of pregnancy-related stroke: A systematic review and meta-analysis. International Journal Of Stroke 2017, 12: 687-697. PMID: 28884652, DOI: 10.1177/1747493017723271.Peer-Reviewed Original ResearchConceptsCerebral venous sinus thrombosisVenous sinus thrombosisPregnancy-related strokeSinus thrombosisStroke incidenceCrude rateSystematic reviewIncidence of strokeHigh-risk populationConclusions StrokePostpartum strokeNonhemorrhagic strokeIschemic strokePregnancy populationStroke riskPerinatal strokePooled analysisSubgroup analysisObstetrical careIncidence rateStroke typeOvid MEDLINEInclusion criteriaStroke ratePregnancy
2015
What’s new in obstetric anesthesia? Focus on preeclampsia
Leffert L. What’s new in obstetric anesthesia? Focus on preeclampsia. International Journal Of Obstetric Anesthesia 2015, 24: 264-271. PMID: 25936785, DOI: 10.1016/j.ijoa.2015.03.008.Peer-Reviewed Original ResearchConceptsMulti-organ systemsHigh-risk patientsPrevalence of preeclampsiaDefinition of preeclampsiaObstetric care teamPregnant patientsFetal effectsObstetric anesthesiaClinical managementCare teamPreeclampsiaTherapeutic interventionsPatientsContemporary dataRecent updatesComorbiditiesMorbidityPregnancyAnesthesiaPathogenesisEtiologyFetusesPrevalenceDiagnosisCareHypertensive Disorders and Pregnancy-Related Stroke
Leffert LR, Clancy CR, Bateman BT, Bryant AS, Kuklina EV. Hypertensive Disorders and Pregnancy-Related Stroke. Obstetrics And Gynecology 2015, 125: 124-131. PMID: 25560114, PMCID: PMC4445352, DOI: 10.1097/aog.0000000000000590.Peer-Reviewed Original ResearchConceptsTraditional stroke risk factorsPregnancy-associated strokeHypertensive disordersPregnancy hospitalizationsStroke risk factorsStroke-related complicationsStroke riskRisk factorsOdds ratioNationwide Inpatient SampleCongenital heart diseaseCross-sectional studyComplication rateStroke hospitalizationsInpatient SampleHeart diseaseNationwide rateHospitalizationPregnancyStrokeLogistic regressionCongenital coagulationDisordersConfidence intervalsComplications
2014
Opioid Abuse and Dependence during Pregnancy
Maeda A, Bateman BT, Clancy CR, Creanga AA, Leffert LR. Opioid Abuse and Dependence during Pregnancy. Anesthesiology 2014, 121: 1158-1165. PMID: 25405293, DOI: 10.1097/aln.0000000000000472.Peer-Reviewed Original ResearchConceptsOpioid abuseObstetrical outcomesIntrauterine growth restrictionNationwide Inpatient SampleObstetrical morbidityPlacental abruptionPreterm laborCesarean deliveryMaternal deathsPremature rupturePregnant womenCardiac arrestRelevant confoundersInpatient SampleGrowth restrictionPreventive strategiesTherapeutic interventionsPregnancyLogistic regressionNationwide trendsHospitalizationPrevalenceAbuseOutcomesUnited States
2010
Management of a parturient with high-grade osteosarcoma of the proximal femur: a multidisciplinary approach
Quaye A, Raskin K, Ecker J, Leffert L. Management of a parturient with high-grade osteosarcoma of the proximal femur: a multidisciplinary approach. International Journal Of Obstetric Anesthesia 2010, 19: 340-342. PMID: 20627530, DOI: 10.1016/j.ijoa.2010.03.013.Peer-Reviewed Original ResearchConceptsHigh-grade osteosarcomaCommon primary malignant bone tumorPrimary malignant bone tumorWeeks of gestationMalignant bone tumorsNewborn baby boyFemoral neck resectionAdjuvant chemotherapyCesarean deliveryMultiparous womenPathologic fractureSpinal anesthesiaSubsequent surgeryLimb salvageThird trimesterOncologic therapyBone tumorsMultidisciplinary planningNeck resectionBaby boyProximal femurOsteosarcomaMultidisciplinary approachPregnancyMothers
2007
Preface
Pian-Smith M, Leffert L. Preface. 2007, xxi-xxii. DOI: 10.1017/cbo9780511586057.001.Peer-Reviewed Original Research