Hormonal regulation of K+-channel messenger RNA in rat myometrium during oestrus cycle and in pregnancy
Boyle M, MacLusky N, Naftolin F, Kaczmarek L. Hormonal regulation of K+-channel messenger RNA in rat myometrium during oestrus cycle and in pregnancy. Nature 1987, 330: 373-375. PMID: 2446134, DOI: 10.1038/330373a0.Peer-Reviewed Original ResearchConceptsChannel messenger RNAUterine smooth muscle cellsSmooth muscle excitabilityEnd of pregnancyPresence of estrogenSmooth muscle cellsIon channelsEstrogen altersPregnant ratsHormonal treatmentMyometrial cellsRat myometriumSteroid hormonesMuscle cellsOestrous cycleCellular excitabilityOestrus cycleVoltage-dependent ion channelsHormonal regulationPregnancyEstrogenExcitabilityElectrical couplingMessenger RNAMessenger RNA speciesXenopus Oocytes Injected with Rat Uterine RNA Express Very Slowly Activating Potassium Currents
Boyle M, Azhderian E, MacLusky N, Naftolin F, Kaczmarek L. Xenopus Oocytes Injected with Rat Uterine RNA Express Very Slowly Activating Potassium Currents. Science 1987, 235: 1221-1224. PMID: 2434999, DOI: 10.1126/science.2434999.Peer-Reviewed Original ResearchConceptsUterine smooth muscleSmooth musclePotassium currentAction potentialsVoltage-dependent potassium currentsInfluence of estrogenUteri of estrogenXenopus Oocytes InjectedOvariectomized ratsRat brainProlonged burstsEstrogenRepetitive burstsNegative membrane potentialsInjected oocytesRatsExcitable tissuesMuscleXenopus oocytesMembrane potentialOocytesDepolarizationMyometriumUterusBrain