2000
Cloning and localization of the hyperpolarization-activated cyclic nucleotide-gated channel family in rat brain
Monteggia L, Eisch A, Tang M, Kaczmarek L, Nestler E. Cloning and localization of the hyperpolarization-activated cyclic nucleotide-gated channel family in rat brain. Brain Research 2000, 81: 129-139. PMID: 11000485, DOI: 10.1016/s0169-328x(00)00155-8.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBrainCloning, MolecularCyclic Nucleotide-Gated Cation ChannelsHumansHyperpolarization-Activated Cyclic Nucleotide-Gated ChannelsIn Situ HybridizationIon ChannelsMaleMembrane PotentialsModels, MolecularMolecular Sequence DataMultigene FamilyMuscle ProteinsNerve Tissue ProteinsOrgan SpecificityPotassium ChannelsProtein Structure, SecondaryRatsRats, Sprague-DawleyRNA, MessengerSequence AlignmentSequence Homology, Amino AcidTranscription, GeneticConceptsRat brainLower brain stem nucleiNeuronal pacemaker activityPrincipal relay nucleiBrain stem nucleiVentral cochlear nucleusAdult rat brainFacial motor nucleusCerebral cortexMotor nucleusStem nucleiTrapezoid bodyCochlear nucleusMamillary bodiesMedial habenulaRelay nucleiHCN1 expressionHCN1-4Olfactory bulbPontine nucleiAdult brainRhythmic firingPacemaker activitySupraoptic nucleusHCN4 expression
1992
Expression of the mRNAs for the Kv3.1 potassium channel gene in the adult and developing rat brain
Perney T, Marshall J, Martin K, Hockfield S, Kaczmarek L. Expression of the mRNAs for the Kv3.1 potassium channel gene in the adult and developing rat brain. Journal Of Neurophysiology 1992, 68: 756-766. PMID: 1432046, DOI: 10.1152/jn.1992.68.3.756.Peer-Reviewed Original ResearchConceptsAdult rat brainRat brainSitu hybridization histochemistryAlpha mRNAThalamic nucleiHigh-frequency firing ratesHybridization histochemistryBeta mRNASubstantia nigra reticulataReticular thalamic nucleusNarrow action potentialsPostnatal day 10Embryonic day 17Alpha mRNA levelsSplice variantsKv3.1 transcriptsProtection assaysHeterogeneous expression patternKv3.1 potassium channel geneOlfactory tubercleVestibular nucleiBrain stemGlobus pallidusSame neuronsInferior colliculus