2024
Tenecteplase versus alteplase for acute ischaemic stroke in the elderly patients: a post hoc analysis of the TRACE-2 trial
Xiong Y, Wang L, Pan Y, Wang M, Schwamm L, Duan C, Campbell B, Li S, Hao M, Wu N, Cao Z, Wu S, Li Z, Wang Y. Tenecteplase versus alteplase for acute ischaemic stroke in the elderly patients: a post hoc analysis of the TRACE-2 trial. Stroke And Vascular Neurology 2024, svn-2023-003048. PMID: 38858097, DOI: 10.1136/svn-2023-003048.Peer-Reviewed Original ResearchSymptomatic intracranial haemorrhageAcute ischaemic strokeModified Rankin ScaleElderly patientsPost hoc analysisAlteplase groupTenecteplase groupHoc analysisAlternative to alteplaseModified Rankin scale 0Ischaemic strokeRisk-benefit profileNon-inferiority clinical trialBenefit-risk profileEfficacy outcomesProportion of participantsReperfusion therapyIntracranial haemorrhageClinical trialsRankin ScaleSymptom onsetTenecteplaseAlteplaseIntravenous thrombolyticsSafety outcomes
2008
Get With the Guidelines–Stroke Is Associated With Sustained Improvement in Care for Patients Hospitalized With Acute Stroke or Transient Ischemic Attack
Schwamm L, Fonarow G, Reeves M, Pan W, Frankel M, Smith E, Ellrodt G, Cannon C, Liang L, Peterson E, LaBresh K. Get With the Guidelines–Stroke Is Associated With Sustained Improvement in Care for Patients Hospitalized With Acute Stroke or Transient Ischemic Attack. Circulation 2008, 119: 107-115. PMID: 19075103, DOI: 10.1161/circulationaha.108.783688.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAcute DiseaseAgedAged, 80 and overEvidence-Based MedicineFemaleGuideline AdherenceHospitalizationHospitals, CommunityHumansIschemic Attack, TransientLogistic ModelsMaleMiddle AgedMultivariate AnalysisProspective StudiesQuality of Health CareRisk FactorsStrokeThrombolytic TherapyConceptsTransient ischemic attackGuidelines-StrokeIschemic attackDeep vein thrombosis prophylaxisNational quality improvement programStroke performance measuresTreatment of strokeEvidence-based guidelinesMain outcome measuresLow-density lipoproteinQuality Improvement ProgramComposite measureDischarge antithromboticsEarly antithromboticsThrombosis prophylaxisIntravenous thrombolyticsAcute strokeIschemic strokeGuideline recommendationsStroke careAtrial fibrillationLipid treatmentCommunity hospitalOutcome measuresSustained improvement