2024
Total Hip Arthroplasty in Patients Who Have Factor V Leiden: Elevated Risks Isolated to Venous Thromboembolism Events
Sanchez J, Jiang W, Dhodapkar M, Radford Z, Rubin L, Grauer J. Total Hip Arthroplasty in Patients Who Have Factor V Leiden: Elevated Risks Isolated to Venous Thromboembolism Events. The Journal Of Arthroplasty 2024, 39: 2421-2426. PMID: 38838962, DOI: 10.1016/j.arth.2024.05.083.Peer-Reviewed Original ResearchFactor V LeidenAdverse eventsChemoprophylactic agentV LeidenMultivariate analysisFactor V Leiden patientsTotal hip arthroplastyPatients to venous thromboembolismLog-rank testIncreased VTE riskVenous thromboembolic eventsElevated riskPerioperative adverse eventsPre-existing comorbiditiesAdministrative claims databaseInherited thrombophiliaThromboembolic eventsElixhauser Comorbidity IndexAdult patientsVenous thromboembolismImplant survivalVTE riskComorbidity indexClaims databaseHip arthroplasty
2021
COVID-positive ankle fracture patients are at increased odds of perioperative surgical complications following open reduction internal fixation surgery
Mercier MR, Galivanche AR, Brand JP, Pathak N, Medvecky MJ, Varthi AG, Rubin LE, Grauer JN. COVID-positive ankle fracture patients are at increased odds of perioperative surgical complications following open reduction internal fixation surgery. PLOS ONE 2021, 16: e0262115. PMID: 34972190, PMCID: PMC8719674, DOI: 10.1371/journal.pone.0262115.Peer-Reviewed Original ResearchConceptsCOVID-positive patientsAnkle fracture surgeryPerioperative adverse eventsAdverse eventsAnkle fracture patientsFracture surgeryFracture patientsOperative interventionAnkle fracturesPropensity matchingCOVID statusOpen reduction internal fixation surgeryPerioperative adverse outcomesPerioperative surgical complicationsMinor adverse eventsPostoperative adverse eventsSerious adverse eventsChronic kidney diseaseCOVID-19 Research DatabaseLong-term outcomesInternal fixation surgeryBasis of agePropensity-score matchingPostoperative complicationsNegative patientsTotal Hip Arthroplasty in Patients With Cerebral Palsy: A Matched Comparison of 90-Day Adverse Events and 5-Year Implant Survival
Moore HG, Gardezi M, Burroughs PJ, Rubin LE, Frumberg DB, Grauer JN. Total Hip Arthroplasty in Patients With Cerebral Palsy: A Matched Comparison of 90-Day Adverse Events and 5-Year Implant Survival. The Journal Of Arthroplasty 2021, 36: 3534-3537. PMID: 34176692, DOI: 10.1016/j.arth.2021.05.039.Peer-Reviewed Original ResearchConceptsTotal hip arthroplastyFive-year implant survivalUrinary tract infectionCerebral palsyImplant survivalAdverse eventsTract infectionsComorbid factorsPeriprosthetic fracturesHigher oddsHip arthroplastyPerioperative urinary tract infectionNinety-day incidencePerioperative adverse eventsLong-term outcomesLog-rank testKaplan-Meier plotsMultivariate logistic regressionPerioperative complicationsPostoperative complicationsCP cohortHospital readmissionMatched ComparisonAdministrative databasesPatientsUnderweight Patients Are the Greatest Risk Body Mass Index Group for 30-Day Perioperative Adverse Events After Total Shoulder Arthroplasty.
Ottesen TD, Hsiang WR, Malpani R, Nicholson AD, Varthi AG, Rubin LE, Grauer JN. Underweight Patients Are the Greatest Risk Body Mass Index Group for 30-Day Perioperative Adverse Events After Total Shoulder Arthroplasty. Journal Of The American Academy Of Orthopaedic Surgeons 2021, 29: e132-e142. PMID: 32568997, DOI: 10.5435/jaaos-d-20-00049.Peer-Reviewed Original ResearchConceptsBody mass indexPerioperative adverse eventsTotal shoulder arthroplastyNormal weight patientsAdverse eventsTSA patientsBMI categoriesUnderweight patientsShoulder arthroplastyNational Surgical Quality Improvement Program databaseElective total shoulder arthroplastyOverweight/obese categoriesRisk-adjusted multivariate regressionsQuality Improvement Program databaseElevated body mass indexBody mass index groupsLower body mass indexPrimary total shoulder arthroplastyNormal BMI patientsComplications of patientsSerious adverse eventsImprovement Program databaseNormal-weight subjectsBMI patientsFragile cohort
2019
Dialysis Dependence Is Associated With Significantly Increased Odds of Perioperative Adverse Events After Geriatric Hip Fracture Surgery Even After Controlling for Demographic Factors and Comorbidities
Ottesen TD, Yurter A, Shultz BN, Galivanche AR, Zogg CK, Bovonratwet P, Rubin LE, Grauer JN. Dialysis Dependence Is Associated With Significantly Increased Odds of Perioperative Adverse Events After Geriatric Hip Fracture Surgery Even After Controlling for Demographic Factors and Comorbidities. JAAOS Global Research And Reviews 2019, 3: e086. PMID: 31592508, PMCID: PMC6754213, DOI: 10.5435/jaaosglobal-d-19-00086.Peer-Reviewed Original ResearchHip fracture surgeryDialysis-dependent patientsPerioperative adverse eventsAdverse eventsFracture surgeryDialysis dependenceDialysis patientsHip fractureGreater oddsNational Surgical Quality Improvement Program databaseGeriatric hip fracture surgeryRisk-adjusted logistic regressionQuality Improvement Program databaseInstitutional cohort studyNational patient populationPreoperative dialysis dependenceMinor adverse eventsHip fracture careImprovement Program databaseMajor adverse eventsDemographic factorsUnplanned readmissionCohort studyPerioperative periodPostoperative day
2018
Underweight Patients Are the Highest-Risk BMI Group for Perioperative Adverse Events after Total Shoulder Arthroplasty
Ottesen T, Hsiang W, Malpani R, Varthi A, Rubin L, Grauer J. Underweight Patients Are the Highest-Risk BMI Group for Perioperative Adverse Events after Total Shoulder Arthroplasty. Journal Of The American College Of Surgeons 2018, 227: s191. DOI: 10.1016/j.jamcollsurg.2018.07.412.Peer-Reviewed Original ResearchPerioperative adverse eventsTotal shoulder arthroplastyUnderweight patientsAdverse eventsBMI groupsShoulder arthroplastyPatientsArthroplastyDialysis is an independent risk factor for perioperative adverse events, readmission, reoperation, and mortality for patients undergoing elective spine surgery
Ottesen TD, McLynn RP, Zogg CK, Shultz BN, Ondeck NT, Bovonratwet P, Bellamkonda KS, Rubin LE, Grauer JN. Dialysis is an independent risk factor for perioperative adverse events, readmission, reoperation, and mortality for patients undergoing elective spine surgery. The Spine Journal 2018, 18: 2033-2042. PMID: 30077772, DOI: 10.1016/j.spinee.2018.04.007.Peer-Reviewed Original ResearchConceptsElective spine surgeryNon-dialysis patientsDialysis-dependent patientsPerioperative adverse eventsAdverse eventsDialysis patientsSpine surgeryUnplanned readmissionCohort studyPatient demographicsRisk factorsNational Surgical Quality Improvement Program databaseRisk-adjusted multivariate regressionsQuality Improvement Program databaseOperating roomDialysis-independent patientsInstitutional cohort studyMinor adverse eventsRetrospective cohort studyElective spinal surgeryImprovement Program databaseIndependent risk factorMajor adverse eventsPercentage of complicationsAdministrative database study