2024
#2598 Risk of vascular access complications in haemodialysis patients initiating dialysis with arteriovenous fistula or arteriovenous graft
Willetts J, Usvyat L, Chaudhuri S, Niklason L, Maddux F. #2598 Risk of vascular access complications in haemodialysis patients initiating dialysis with arteriovenous fistula or arteriovenous graft. Nephrology Dialysis Transplantation 2024, 39: gfae069-1550-2598. DOI: 10.1093/ndt/gfae069.1550.Peer-Reviewed Original ResearchVascular access complication ratesArteriovenous fistulaEnd-stage kidney diseaseArteriovenous graftsVA complicationsVascular accessIn-center hemodialysisInitial VAComorbid conditionsDuration of follow-upAssociated with increased riskComplication eventsHistory of myocardial infarctionCongestive heart failureVascular access complicationsDiabetic ptsRisk of vascular access complicationsComplication rateDemographic characteristicsIncreased BMIDocumented thrombosisIn-center hemodialysis patientsContinuous hemodialysisHigher BMIHaemodialysis patients
2016
Bioengineered human acellular vessels for dialysis access in patients with end-stage renal disease: two phase 2 single-arm trials
Lawson JH, Glickman MH, Ilzecki M, Jakimowicz T, Jaroszynski A, Peden EK, Pilgrim AJ, Prichard HL, Guziewicz M, Przywara S, Szmidt J, Turek J, Witkiewicz W, Zapotoczny N, Zubilewicz T, Niklason LE. Bioengineered human acellular vessels for dialysis access in patients with end-stage renal disease: two phase 2 single-arm trials. The Lancet 2016, 387: 2026-2034. PMID: 27203778, PMCID: PMC4915925, DOI: 10.1016/s0140-6736(16)00557-2.Peer-Reviewed Original ResearchConceptsHuman acellular vesselEnd-stage renal diseaseAcellular vesselsPrimary patencySecondary patencyRenal diseaseDialysis accessHaemodialysis accessPhase 2 single-arm trialSingle-arm phase 2 trialPolytetrafluoroethylene arteriovenous graftsPhase 2 trialDialysis access graftsSingle-arm trialArms of patientsPrimary endpointChronic haemodialysisAccess graftsUS National InstitutesArteriovenous graftsVenous anastomosisCensoring eventIntimal hyperplasiaPatencyPatients